SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 2v3b RUBREDOXIN 2
(Pseudomonas
aeruginosa) 		5 / 8 CYH B   9
ASP B  41
VAL B   8
CYH B  39
GLY B  43
 FE  B1054 (-2.3A)
None
FE  B1054 ( 4.9A)
FE  B1054 (-2.2A)
None
 1.49A 1ekjA-2v3bB:
undetectable
1ekjB-2v3bB:
undetectable		 1ekjA-2v3bB:
14.49
1ekjB-2v3bB:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A 147
LEU A 171
LEU A 150
VAL A 236
ALA A 142
PHE A 138
 None
 1.29A 1gseA-2v3bA:
undetectable		 1gseA-2v3bA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A 147
LEU A 171
LEU A 150
VAL A 236
ALA A 142
PHE A 138
 None
 1.27A 1gseB-2v3bA:
undetectable		 1gseB-2v3bA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		6 / 12 ARG A 147
LEU A 171
LEU A 150
VAL A 236
LEU A 234
PHE A 138
 None
 1.39A 1gseB-2v3bA:
undetectable		 1gseB-2v3bA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 ASP A  27
GLY A  28
THR A  30
PRO A  31
 None
 0.95A 1n4fA-2v3bA:
undetectable		 1n4fA-2v3bA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 2v3b RUBREDOXIN 2
(Pseudomonas
aeruginosa) 		4 / 5 GLN B   5
TRP B  30
LEU B  19
TRP B  37
 None
 1.40A 1ulvA-2v3bB:
undetectable		 1ulvA-2v3bB:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 275
VAL A 106
ILE A  10
GLY A  11
TYR A  17
 None
None
FAD  A1385 (-4.7A)
FAD  A1385 (-3.4A)
None
 1.41A 3hgiA-2v3bA:
undetectable		 3hgiA-2v3bA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A  45
ARG A 244
LEU A 241
 FAD  A1385 (-2.6A)
FAD  A1385 ( 4.6A)
None
 1.31A 3v4tE-2v3bA:
undetectable		 3v4tE-2v3bA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A   7
ASP A 104
LEU A 105
ASN A 271
ILE A   9
 None
 1.28A 3wdmA-2v3bA:
undetectable		 3wdmA-2v3bA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 138
ALA A 238
LEU A 151
VAL A 148
LEU A 149
 None
 0.96A 4g1bA-2v3bA:
2.9		 4g1bA-2v3bA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 245
LEU A 247
ALA A 248
LEU A 107
GLY A 276
 None
None
None
None
FAD  A1385 (-3.5A)
 1.02A 4xi3C-2v3bA:
undetectable		 4xi3C-2v3bA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 265
LEU A 292
LEU A 275
LEU A  19
ALA A  15
 None
None
None
None
FAD  A1385 (-3.2A)
 1.07A 5dqfA-2v3bA:
undetectable		 5dqfA-2v3bA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 2v3b RUBREDOXIN 2
(Pseudomonas
aeruginosa) 		3 / 3 VAL B  44
GLN B   5
CYH B   9
 None
None
FE  B1054 (-2.3A)
 0.91A 5icxC-2v3bB:
undetectable
5icxF-2v3bB:
undetectable		 5icxC-2v3bB:
13.08
5icxF-2v3bB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 2v3b RUBREDOXIN REDUCTASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 150
ALA A 238
LEU A 197
THR A 321
 None
 0.77A 6f88B-2v3bA:
undetectable		 6f88B-2v3bA:
12.50