SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2v3m NAF1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 153
LEU A 143
ARG A 162
THR A 138
 None
 1.02A 3ag2N-2v3mA:
undetectable
3ag2W-2v3mA:
undetectable		 3ag2N-2v3mA:
12.45
3ag2W-2v3mA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2v3m NAF1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 153
LEU A 143
ARG A 162
THR A 138
 None
 0.91A 3ag4N-2v3mA:
undetectable
3ag4W-2v3mA:
undetectable		 3ag4N-2v3mA:
12.45
3ag4W-2v3mA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2v3m NAF1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 208
ILE A 151
ILE A 153
LEU A 143
GLY A 179
 None
 0.96A 4nkvB-2v3mA:
undetectable		 4nkvB-2v3mA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2v3m NAF1
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 153
LEU A 143
ARG A 162
THR A 138
 None
 1.02A 5b1aN-2v3mA:
undetectable
5b1aW-2v3mA:
undetectable		 5b1aN-2v3mA:
12.45
5b1aW-2v3mA:
23.91