SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 PRO A  38
THR A  42
PRO A  43
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.3A)
 0.50A 1h4oB-2v41A:
18.5		 1h4oB-2v41A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 PRO A  38
THR A  42
PRO A  43
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.3A)
 0.48A 1h4oG-2v41A:
18.4		 1h4oG-2v41A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 LEU A 157
PRO A 135
VAL A  64
GLY A  63
 None
 0.99A 1hrkA-2v41A:
undetectable		 1hrkA-2v41A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 LEU A 157
PRO A 135
VAL A  64
GLY A  63
 None
 1.01A 1hrkB-2v41A:
undetectable		 1hrkB-2v41A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 PRO A  38
THR A  42
PRO A  43
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.3A)
 0.48A 1oc3A-2v41A:
18.3		 1oc3A-2v41A:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		5 / 9 PRO A  38
THR A  42
PRO A  43
SER A  45
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.3A)
 0.52A 1urmA-2v41A:
17.9		 1urmA-2v41A:
25.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.16A 2v2gA-2v41A:
34.8
2v2gB-2v41A:
34.7		 2v2gA-2v41A:
100.00
2v2gB-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.17A 2v2gA-2v41A:
34.8
2v2gB-2v41A:
34.7		 2v2gA-2v41A:
100.00
2v2gB-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.14A 2v2gC-2v41A:
34.7
2v2gD-2v41A:
34.7		 2v2gC-2v41A:
100.00
2v2gD-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.16A 2v2gC-2v41A:
34.7
2v2gD-2v41A:
34.7		 2v2gC-2v41A:
100.00
2v2gD-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
ALA A 147
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
BEZ  A1222 ( 3.7A)
 0.18A 2v32A-2v41A:
34.6
2v32B-2v41A:
34.5		 2v32A-2v41A:
100.00
2v32B-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
ALA A 147
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
BEZ  A1222 ( 3.7A)
 0.17A 2v32A-2v41A:
34.6
2v32B-2v41A:
34.5		 2v32A-2v41A:
100.00
2v32B-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.17A 2v32C-2v41A:
34.6
2v32D-2v41A:
34.6		 2v32C-2v41A:
100.00
2v32D-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 8 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.17A 2v32C-2v41A:
34.6
2v32D-2v41A:
34.6		 2v32C-2v41A:
100.00
2v32D-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		8 / 9 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
ALA A 147
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
BEZ  A1222 ( 3.7A)
 0.01A 2v41A-2v41A:
37.1
2v41B-2v41A:
34.6		 2v41A-2v41A:
100.00
2v41B-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		8 / 9 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
ALA A 147
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
BEZ  A1222 ( 3.7A)
 0.14A 2v41A-2v41A:
37.1
2v41B-2v41A:
34.6		 2v41A-2v41A:
100.00
2v41B-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.24A 2v41C-2v41A:
33.7
2v41D-2v41A:
33.8		 2v41C-2v41A:
100.00
2v41D-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.16A 2v41C-2v41A:
33.7
2v41D-2v41A:
33.8		 2v41C-2v41A:
100.00
2v41D-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.20A 2v41E-2v41A:
34.5
2v41F-2v41A:
34.7		 2v41E-2v41A:
100.00
2v41F-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		6 / 7 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.17A 2v41E-2v41A:
34.5
2v41F-2v41A:
34.7		 2v41E-2v41A:
100.00
2v41F-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
ALA A 147
 BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
BEZ  A1222 ( 3.7A)
 0.24A 2v41G-2v41A:
34.3
2v41H-2v41A:
34.5		 2v41G-2v41A:
100.00
2v41H-2v41A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		7 / 8 PRO A  38
THR A  42
PRO A  43
VAL A  44
SER A  45
GLU A 117
ARG A 128
 BEZ  A1222 ( 4.6A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.2A)
BEZ  A1222 (-3.7A)
BEZ  A1222 (-3.0A)
BEZ  A1222 (-3.6A)
BEZ  A1222 (-3.3A)
 0.20A 2v41G-2v41A:
34.3
2v41H-2v41A:
34.5		 2v41G-2v41A:
100.00
2v41H-2v41A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		3 / 3 PRO A  38
THR A 126
LEU A  69
 BEZ  A1222 ( 4.6A)
None
None
 0.70A 3ttrA-2v41A:
undetectable		 3ttrA-2v41A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 8 LEU A  69
ILE A  67
GLY A  32
ILE A 133
 None
 0.78A 3wxoA-2v41A:
undetectable		 3wxoA-2v41A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		4 / 6 GLY A  32
PHE A  23
ILE A  67
PHE A  12
 None
 1.06A 4qogA-2v41A:
undetectable
4qogB-2v41A:
undetectable		 4qogA-2v41A:
22.85
4qogB-2v41A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		5 / 12 PHE A   9
ILE A   3
LEU A 141
VAL A 130
LEU A 106
 None
 1.17A 5byjA-2v41A:
undetectable		 5byjA-2v41A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 2v41 PEROXIREDOXIN 6.
(Arenicola
marina) 		3 / 3 HIS A  37
ASP A  40
HIS A  77
 None
 0.81A 5oexA-2v41A:
undetectable		 5oexA-2v41A:
20.89