SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.45A 1dfoB-2v5dA:
undetectable		 1dfoB-2v5dA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.45A 1dfoA-2v5dA:
undetectable		 1dfoA-2v5dA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.46A 1dfoD-2v5dA:
undetectable		 1dfoD-2v5dA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLU A 186
TYR A 215
TYR A 213
PRO A 192
 None
 1.45A 1dfoC-2v5dA:
undetectable		 1dfoC-2v5dA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 LEU A 162
ALA A 143
VAL A  43
TYR A 133
LEU A  53
 None
 1.27A 1kt6A-2v5dA:
undetectable		 1kt6A-2v5dA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 GLY A 414
GLU A 374
GLY A 494
ASP A 416
ASN A 453
 None
 1.11A 1n2xA-2v5dA:
undetectable		 1n2xA-2v5dA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 8 VAL A 370
TYR A 335
ASP A 297
TRP A 394
 None
 1.09A 1pk2A-2v5dA:
undetectable		 1pk2A-2v5dA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.94A 1tt0A-2v5dA:
1.9		 1tt0A-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.94A 1tt0B-2v5dA:
undetectable		 1tt0B-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.92A 1tt0C-2v5dA:
1.5		 1tt0C-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.93A 1tt0D-2v5dA:
1.3		 1tt0D-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 GLY A 494
ARG A 484
TYR A 397
 None
 0.58A 2opxA-2v5dA:
undetectable		 2opxA-2v5dA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 9 ILE A 361
PHE A 353
ALA A 354
VAL A 357
 None
 0.77A 2vufA-2v5dA:
2.6		 2vufA-2v5dA:
23.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W4X_A_STZA1591_1
(O-GLCNACASE BT_4395)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		9 / 11 TYR A 335
THR A 366
VAL A 370
TRP A 394
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
 None
 0.52A 2w4xA-2v5dA:
46.4		 2w4xA-2v5dA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 LYS A 218
TYR A 295
ASP A 297
VAL A 331
TYR A 335
 None
 1.17A 2x0yA-2v5dA:
52.0		 2x0yA-2v5dA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		11 / 12 LYS A 218
TYR A 295
VAL A 331
TYR A 335
THR A 366
VAL A 370
TRP A 394
ASN A 396
VAL A 399
ASP A 401
ASN A 429
 None
 0.58A 2x0yA-2v5dA:
52.0		 2x0yA-2v5dA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 LYS A 218
ASP A 297
VAL A 331
TYR A 335
TRP A 490
 None
 1.14A 2x0yB-2v5dA:
52.0		 2x0yB-2v5dA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		6 / 12 LYS A 218
ASP A 298
VAL A 399
ASP A 401
TYR A 402
TRP A 490
 None
 1.17A 2x0yB-2v5dA:
52.0		 2x0yB-2v5dA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0Y_B_X0TB1625_1
(O-GLCNACASE NAGJ)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		11 / 12 LYS A 218
VAL A 331
TYR A 335
THR A 366
TRP A 394
ASN A 396
VAL A 399
ASP A 401
TYR A 402
ASN A 429
TRP A 490
 None
 0.56A 2x0yB-2v5dA:
52.0		 2x0yB-2v5dA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.03A 2x45A-2v5dA:
undetectable		 2x45A-2v5dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.07A 2x45B-2v5dA:
undetectable		 2x45B-2v5dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.06A 2x45C-2v5dA:
undetectable		 2x45C-2v5dA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ILE A 441
MET A 431
PRO A 430
VAL A 608
 None
 1.13A 2ygoA-2v5dA:
undetectable		 2ygoA-2v5dA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 VAL A 763
LEU A 674
TYR A 687
ILE A 698
 None
 0.93A 3avpA-2v5dA:
undetectable		 3avpA-2v5dA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 SER A 493
TYR A 397
VAL A 399
TYR A 402
 None
 1.14A 3bu1A-2v5dA:
undetectable		 3bu1A-2v5dA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ASP A 497
ARG A 495
ARG A 502
SER A 611
 None
 1.42A 3ckzA-2v5dA:
undetectable		 3ckzA-2v5dA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.94A 3lskB-2v5dA:
undetectable		 3lskB-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 GLN A 750
PHE A 757
HIS A 658
ASN A 695
 None
 0.97A 3lskD-2v5dA:
1.9		 3lskD-2v5dA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 GLY A 755
LYS A 756
GLU A 667
GLY A 753
 None
 1.05A 3onnA-2v5dA:
undetectable		 3onnA-2v5dA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 GLY A 190
GLU A 432
THR A 400
ARG A 198
GLY A 187
 None
 1.44A 3x2qA-2v5dA:
3.3
3x2qB-2v5dA:
0.0
3x2qT-2v5dA:
0.0		 3x2qA-2v5dA:
22.81
3x2qB-2v5dA:
16.55
3x2qT-2v5dA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 ARG A 198
GLY A 187
GLY A 190
GLU A 432
THR A 400
 None
 1.45A 3x2qG-2v5dA:
0.0
3x2qN-2v5dA:
2.1
3x2qO-2v5dA:
0.0		 3x2qG-2v5dA:
10.70
3x2qN-2v5dA:
22.81
3x2qO-2v5dA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PRO A 368
GLY A 369
ASN A 373
GLU A 374
 None
 0.65A 3zqtA-2v5dA:
undetectable		 3zqtA-2v5dA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ARG A 502
LEU A 525
MET A 505
ASP A 506
 None
 1.49A 4cevD-2v5dA:
2.4
4cevE-2v5dA:
2.4		 4cevD-2v5dA:
20.32
4cevE-2v5dA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 ASP A  75
ASP A 252
ASN A  77
ASP A 150
 None
 1.32A 4gkhJ-2v5dA:
undetectable		 4gkhJ-2v5dA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 TYR A 295
VAL A 254
PHE A 425
GLY A 256
THR A 212
 None
 1.14A 4mm6A-2v5dA:
undetectable		 4mm6A-2v5dA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 LEU A 512
LEU A 525
ILE A 522
LEU A 521
LEU A 576
 None
 1.03A 4odoA-2v5dA:
undetectable		 4odoA-2v5dA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 LEU A 512
LEU A 525
ILE A 522
LEU A 521
LEU A 576
 None
 1.02A 4odoC-2v5dA:
undetectable		 4odoC-2v5dA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 7 GLY A 564
GLN A 563
TYR A 526
SER A 568
 None
 1.17A 4ws0A-2v5dA:
undetectable		 4ws0A-2v5dA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 12 ILE A 726
TYR A 687
VAL A 763
ASP A 650
THR A 655
 None
None
None
None
CA  A1770 (-3.8A)
 1.29A 4xe0A-2v5dA:
2.0		 4xe0A-2v5dA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 5 ARG A 224
PRO A 259
ILE A 261
ASP A 262
 None
 1.34A 4z4hA-2v5dA:
2.9		 4z4hA-2v5dA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 GLY A 190
GLU A 432
THR A 400
ARG A 198
GLY A 187
 None
 1.50A 5b1aA-2v5dA:
3.2
5b1aB-2v5dA:
0.0
5b1aT-2v5dA:
0.0		 5b1aA-2v5dA:
22.81
5b1aB-2v5dA:
16.55
5b1aT-2v5dA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 GLY A 190
GLU A 432
THR A 400
ARG A 198
GLY A 187
 None
 1.43A 5b3sA-2v5dA:
2.9
5b3sB-2v5dA:
0.0
5b3sT-2v5dA:
0.0		 5b3sA-2v5dA:
22.81
5b3sB-2v5dA:
16.55
5b3sT-2v5dA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PHE A 612
HIS A 481
MET A 505
LEU A 561
 None
 1.44A 5dzka-2v5dA:
2.0
5dzko-2v5dA:
undetectable		 5dzka-2v5dA:
14.56
5dzko-2v5dA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		4 / 6 PHE A 612
SER A 605
HIS A 481
LEU A 561
 None
 1.46A 5dzka-2v5dA:
2.0
5dzko-2v5dA:
undetectable		 5dzka-2v5dA:
14.56
5dzko-2v5dA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 ASN A  90
SER A  64
SER A  65
 None
 0.65A 5gsnA-2v5dA:
2.4		 5gsnA-2v5dA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 LEU A 162
LEU A 135
ARG A  83
 None
 0.64A 5hnzB-2v5dA:
1.8		 5hnzB-2v5dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 ALA A 535
ASN A 538
LEU A 539
 None
 0.44A 5i1nC-2v5dA:
undetectable		 5i1nC-2v5dA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		3 / 3 SER A 303
ALA A 304
THR A 356
 None
 0.57A 5n0xB-2v5dA:
undetectable		 5n0xB-2v5dA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 ARG A 198
GLY A 187
GLY A 190
GLU A 432
THR A 400
 None
 1.47A 5wauG-2v5dA:
0.0
5waua-2v5dA:
2.7
5waub-2v5dA:
0.0		 5wauG-2v5dA:
10.70
5waua-2v5dA:
22.81
5waub-2v5dA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_G_CHDG101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 ARG A 198
GLY A 187
GLY A 190
GLU A 432
THR A 400
 None
 1.41A 5z84G-2v5dA:
0.0
5z84N-2v5dA:
3.1
5z84O-2v5dA:
0.0		 5z84G-2v5dA:
10.70
5z84N-2v5dA:
22.81
5z84O-2v5dA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 10 ARG A 198
GLY A 187
GLY A 190
GLU A 432
THR A 400
 None
 1.42A 5z85G-2v5dA:
0.0
5z85N-2v5dA:
3.2
5z85O-2v5dA:
0.0		 5z85G-2v5dA:
10.70
5z85N-2v5dA:
22.81
5z85O-2v5dA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 2v5d O-GLCNACASE NAGJ
(Clostridium
perfringens) 		5 / 11 ASN A 487
THR A 489
THR A 372
GLY A 369
ASP A 336
 None
 1.40A 6mb5A-2v5dA:
undetectable		 6mb5A-2v5dA:
6.92