SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 2v5f PROLYL 4-HYDROXYLASE
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 5 LEU A 177
LEU A 194
CYH A 150
THR A 146
 None
 1.39A 2oaxD-2v5fA:
undetectable		 2oaxD-2v5fA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2v5f PROLYL 4-HYDROXYLASE
SUBUNIT ALPHA-1
(Homo
sapiens) 		4 / 6 GLN A 200
TYR A 196
PHE A 231
LEU A 204
 None
 1.37A 3tgvB-2v5fA:
undetectable		 3tgvB-2v5fA:
20.14