SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		4 / 7 ASN C  45
THR C  49
GLY C  47
ASP C  77
 None
 0.95A 1bu5A-2v5qC:
undetectable		 1bu5A-2v5qC:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		5 / 11 ILE C  62
LEU C  51
HIS C  69
LEU C  67
ALA C  71
 None
 1.05A 4p65E-2v5qC:
undetectable
4p65F-2v5qC:
undetectable
4p65J-2v5qC:
undetectable
4p65L-2v5qC:
undetectable		 4p65E-2v5qC:
6.67
4p65F-2v5qC:
13.51
4p65J-2v5qC:
13.51
4p65L-2v5qC:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		5 / 12 VAL C  30
LEU C  18
LEU C  51
ILE C  62
ALA C  71
 None
 1.01A 4p65B-2v5qC:
undetectable
4p65D-2v5qC:
undetectable
4p65I-2v5qC:
undetectable
4p65J-2v5qC:
undetectable		 4p65B-2v5qC:
13.51
4p65D-2v5qC:
13.51
4p65I-2v5qC:
6.67
4p65J-2v5qC:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		3 / 3 MET C  89
ASP C 110
PHE C 109
 None
 0.99A 4xeyA-2v5qC:
undetectable		 4xeyA-2v5qC:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		3 / 3 MET C  89
ASP C 110
PHE C 109
 None
 1.01A 4xeyB-2v5qC:
undetectable		 4xeyB-2v5qC:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 2v5q DESIGN ANKYRIN
REPEAT PROTEIN
(unidentified) 		4 / 4 ILE C  62
LEU C  51
HIS C  69
ALA C  71
 None
 0.98A 6ck2C-2v5qC:
undetectable
6ck2D-2v5qC:
undetectable		 6ck2C-2v5qC:
6.67
6ck2D-2v5qC:
12.16