SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 2v5t NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 6 LEU A 250
ILE A 258
ARG A 269
TYR A 279
 None
 1.09A 1db1A-2v5tA:
undetectable		 1db1A-2v5tA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2v5t NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		3 / 3 PHE A 295
VAL A 268
ILE A 271
 None
 0.61A 4emaA-2v5tA:
undetectable		 4emaA-2v5tA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2v5t NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 5 PRO A 209
ASP A 290
ILE A 242
VAL A 280
 None
 1.24A 4hytA-2v5tA:
undetectable		 4hytA-2v5tA:
13.54