SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 2v6u PTERIN-4A-CARBINOLAM
INE DEHYDRATASE
(Toxoplasma
gondii) 		4 / 6 ALA A  90
LYS A  93
ASP A  97
ALA A  98
 None
 0.36A 1iwhA-2v6uA:
undetectable		 1iwhA-2v6uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2v6u PTERIN-4A-CARBINOLAM
INE DEHYDRATASE
(Toxoplasma
gondii) 		4 / 8 VAL A  74
ASN A  64
ILE A  33
MET A  95
 None
NA  A2104 ( 4.5A)
None
None
 1.06A 4iilA-2v6uA:
undetectable		 4iilA-2v6uA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 2v6u PTERIN-4A-CARBINOLAM
INE DEHYDRATASE
(Toxoplasma
gondii) 		3 / 3 ARG A  35
ASP A  96
TRP A  24
 None
 1.04A 4xdqA-2v6uA:
undetectable		 4xdqA-2v6uA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2v6u PTERIN-4A-CARBINOLAM
INE DEHYDRATASE
(Toxoplasma
gondii) 		3 / 3 ASP A  73
ASN A  70
GLN A  38
 None
 0.72A 5k7uA-2v6uA:
undetectable		 5k7uA-2v6uA:
19.47