SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		3 / 3 PHE A 145
LEU A  29
SER A  58
 None
 0.66A 1e7aA-2v73A:
undetectable		 1e7aA-2v73A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ILE A  40
PHE A 135
GLY A  56
ILE A 146
 None
 0.78A 2qwxA-2v73A:
undetectable
2qwxB-2v73A:
undetectable		 2qwxA-2v73A:
21.43
2qwxB-2v73A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 ILE A  40
ILE A 110
SER A  53
GLU A  79
 None
None
None
SIA  A1190 (-3.1A)
 0.59A 3ua5B-2v73A:
undetectable		 3ua5B-2v73A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 LEU A 108
TYR A  78
ILE A 133
GLY A  38
 None
 0.93A 4eq4A-2v73A:
undetectable		 4eq4A-2v73A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 7 LEU A 108
TYR A  78
ILE A 133
GLY A  38
 None
 0.95A 4eqlA-2v73A:
undetectable		 4eqlA-2v73A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ASN A 104
PHE A  99
VAL A  97
LEU A  54
 None
 1.05A 4f5zA-2v73A:
undetectable		 4f5zA-2v73A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 5 PHE A  32
THR A  39
PHE A 135
ILE A   8
 None
 1.26A 4jx1E-2v73A:
undetectable		 4jx1E-2v73A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 6 LEU A 108
TYR A  78
ILE A 133
GLY A  38
 None
 1.02A 4l39A-2v73A:
undetectable		 4l39A-2v73A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 8 ILE A  40
PHE A 135
GLY A  56
ILE A 146
 None
 0.81A 4qogA-2v73A:
undetectable
4qogB-2v73A:
undetectable		 4qogA-2v73A:
21.43
4qogB-2v73A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 5 ASN A  61
ASP A  59
ASN A  65
ASP A  88
 None
 1.25A 5vooA-2v73A:
undetectable		 5vooA-2v73A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 5 ASN A  61
ASP A  59
ASN A  65
ASP A  88
 None
 1.26A 5vooC-2v73A:
undetectable		 5vooC-2v73A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		4 / 5 ASN A  61
ASP A  59
ASN A  65
ASP A  88
 None
 1.26A 5vooE-2v73A:
undetectable		 5vooE-2v73A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 12 LEU A  69
VAL A  71
PHE A  44
ASN A 121
VAL A 125
 None
 1.23A 6drxA-2v73A:
undetectable		 6drxA-2v73A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 10 LEU A  57
GLY A 147
ILE A 146
ILE A 169
ILE A  40
 None
 1.04A 6ebpD-2v73A:
undetectable		 6ebpD-2v73A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 11 LEU A  57
GLY A 147
ILE A 146
ILE A 169
ILE A  40
 None
 1.07A 6ebzB-2v73A:
undetectable		 6ebzB-2v73A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2v73 PUTATIVE
EXO-ALPHA-SIALIDASE
(Clostridium
perfringens) 		5 / 11 LEU A  57
GLY A 147
ILE A 146
ILE A 169
ILE A  40
 None
 1.06A 6ebzD-2v73A:
undetectable		 6ebzD-2v73A:
18.48