SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v7c ORPHAN NUCLEAR
RECEPTOR NR1D2
(Homo
sapiens) 		3 / 3 SER A 569
GLU A 571
GLU A 570
 None
 0.62A 1eqbD-2v7cA:
undetectable		 1eqbD-2v7cA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2v7c ORPHAN NUCLEAR
RECEPTOR NR1D2
(Homo
sapiens) 		3 / 3 SER A 569
GLU A 571
GLU A 570
 None
 0.62A 1eqbB-2v7cA:
undetectable		 1eqbB-2v7cA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2v7c ORPHAN NUCLEAR
RECEPTOR NR1D2
(Homo
sapiens) 		3 / 3 LEU A 482
MET A 486
ASP A 515
 None
 0.81A 4j7xB-2v7cA:
undetectable		 4j7xB-2v7cA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2v7c ORPHAN NUCLEAR
RECEPTOR NR1D2
(Homo
sapiens) 		3 / 3 LYS A 403
SER A 465
SER A 408
 None
 1.13A 6gbfA-2v7cA:
undetectable		 6gbfA-2v7cA:
18.83