SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v7y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.12A 1c8lA-2v7yA:
undetectable		 1c8lA-2v7yA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.08A 1gfzA-2v7yA:
undetectable		 1gfzA-2v7yA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.08A 1l5qA-2v7yA:
undetectable		 1l5qA-2v7yA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.07A 1l5qB-2v7yA:
undetectable		 1l5qB-2v7yA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.03A 1l7xA-2v7yA:
undetectable		 1l7xA-2v7yA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.06A 1l7xB-2v7yA:
undetectable		 1l7xB-2v7yA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		3 / 3 THR A  36
PRO A  28
TYR A 100
 None
 0.94A 2dxrA-2v7yA:
undetectable		 2dxrA-2v7yA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 7 ILE A 370
ARG A 425
PHE A 426
ILE A 468
 None
 0.97A 2q6hA-2v7yA:
undetectable		 2q6hA-2v7yA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 7 ILE A 370
ARG A 425
PHE A 426
ILE A 468
 None
 0.95A 2qb4A-2v7yA:
undetectable		 2qb4A-2v7yA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 8 SER A   2
GLY A 132
GLU A 138
ILE A   7
 None
 0.88A 3aodA-2v7yA:
undetectable		 3aodA-2v7yA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 5 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.12A 3bcrA-2v7yA:
undetectable		 3bcrA-2v7yA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 VAL A 309
ILE A 322
ILE A 303
PRO A 300
ILE A 307
 None
 1.18A 3clbD-2v7yA:
undetectable		 3clbD-2v7yA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 LEU A   9
ASP A 337
VAL A 340
GLY A 169
PRO A 117
 None
ADP  A1505 ( 4.6A)
None
ADP  A1505 (-3.4A)
PO4  A1506 ( 4.4A)
 0.94A 3cywA-2v7yA:
undetectable		 3cywA-2v7yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.09A 3dd1A-2v7yA:
undetectable		 3dd1A-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.07A 3dd1B-2v7yA:
undetectable		 3dd1B-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.08A 3ddsA-2v7yA:
undetectable		 3ddsA-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.06A 3ddsB-2v7yA:
undetectable		 3ddsB-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.09A 3ddwA-2v7yA:
undetectable		 3ddwA-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.08A 3ddwB-2v7yA:
undetectable		 3ddwB-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 VAL A 309
ILE A 322
ILE A 303
PRO A 300
ILE A 307
 None
 1.16A 3hbbD-2v7yA:
undetectable		 3hbbD-2v7yA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		3 / 3 CYH A  15
PRO A  37
ASP A 337
 None
None
ADP  A1505 ( 4.6A)
 0.93A 3hlwB-2v7yA:
undetectable		 3hlwB-2v7yA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 9 ASP A   8
ILE A   7
GLY A 348
ILE A 351
ILE A 114
 MG  A1507 ( 4.1A)
None
None
None
None
 0.99A 3nu4A-2v7yA:
undetectable		 3nu4A-2v7yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 LEU A   9
GLY A 132
ILE A   5
VAL A 109
ILE A   7
 None
 0.96A 3s43B-2v7yA:
undetectable		 3s43B-2v7yA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 0.99A 3uboB-2v7yA:
undetectable		 3uboB-2v7yA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 THR A 147
PRO A 146
TYR A 119
ILE A   7
ILE A 142
 None
 1.34A 4eb6B-2v7yA:
undetectable
4eb6C-2v7yA:
undetectable		 4eb6B-2v7yA:
21.58
4eb6C-2v7yA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4jksA-2v7yA:
undetectable		 4jksA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4jksB-2v7yA:
undetectable		 4jksB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4jkuA-2v7yA:
undetectable		 4jkuA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4jkuB-2v7yA:
undetectable		 4jkuB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k8cA-2v7yA:
undetectable		 4k8cA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4k8cB-2v7yA:
undetectable		 4k8cB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4k8kA-2v7yA:
undetectable		 4k8kA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k8kB-2v7yA:
undetectable		 4k8kB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k8pA-2v7yA:
undetectable		 4k8pA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.04A 4k8pB-2v7yA:
undetectable		 4k8pB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4k8tA-2v7yA:
undetectable		 4k8tA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.05A 4k8tB-2v7yA:
undetectable		 4k8tB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k93A-2v7yA:
undetectable		 4k93A-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k93B-2v7yA:
undetectable		 4k93B-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k9cA-2v7yA:
undetectable		 4k9cA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4k9cB-2v7yA:
undetectable		 4k9cB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4k9iA-2v7yA:
undetectable		 4k9iA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.05A 4k9iB-2v7yA:
undetectable		 4k9iB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4kadA-2v7yA:
undetectable		 4kadA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4kadB-2v7yA:
undetectable		 4kadB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4kahA-2v7yA:
undetectable		 4kahA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4kahB-2v7yA:
undetectable		 4kahB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4kalA-2v7yA:
undetectable		 4kalA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4kalB-2v7yA:
undetectable		 4kalB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4kanA-2v7yA:
undetectable		 4kanA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4kanB-2v7yA:
undetectable		 4kanB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.05A 4kbeA-2v7yA:
undetectable		 4kbeA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4kbeB-2v7yA:
undetectable		 4kbeB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4lbgA-2v7yA:
undetectable		 4lbgA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.01A 4lbgB-2v7yA:
undetectable		 4lbgB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4lbxA-2v7yA:
undetectable		 4lbxA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4lbxB-2v7yA:
undetectable		 4lbxB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4lc4A-2v7yA:
undetectable		 4lc4A-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4lc4B-2v7yA:
undetectable		 4lc4B-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.03A 4lcaA-2v7yA:
undetectable		 4lcaA-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 ASN A 194
GLY A 170
GLY A 171
SER A  66
ASP A 200
 None
ADP  A1505 (-3.5A)
None
None
None
 1.02A 4lcaB-2v7yA:
undetectable		 4lcaB-2v7yA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		3 / 3 HIS A 331
VAL A 289
LEU A 164
 None
 0.74A 4m2vA-2v7yA:
undetectable		 4m2vA-2v7yA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 LEU A   9
ASP A 337
VAL A 340
GLY A 169
PRO A 117
 None
ADP  A1505 ( 4.6A)
None
ADP  A1505 (-3.4A)
PO4  A1506 ( 4.4A)
 0.91A 4njuA-2v7yA:
undetectable		 4njuA-2v7yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 LEU A   9
ASP A 337
VAL A 340
GLY A 169
PRO A 117
 None
ADP  A1505 ( 4.6A)
None
ADP  A1505 (-3.4A)
PO4  A1506 ( 4.4A)
 0.92A 4njuC-2v7yA:
undetectable		 4njuC-2v7yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		3 / 3 CYH A  15
PRO A  37
ASP A 337
 None
None
ADP  A1505 ( 4.6A)
 0.93A 4pm5A-2v7yA:
undetectable		 4pm5A-2v7yA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 LEU A 196
LEU A 168
VAL A 289
LEU A 164
LEU A 326
 None
 1.12A 4po0A-2v7yA:
2.5		 4po0A-2v7yA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 LEU A 196
LEU A 168
VAL A 289
LEU A 164
VAL A 306
 None
 1.18A 4po0A-2v7yA:
2.5		 4po0A-2v7yA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 THR A 172
GLY A 197
ASP A 193
ASN A 194
THR A  11
 PO4  A1506 (-2.9A)
None
None
None
PO4  A1506 ( 3.4A)
 1.31A 4pooA-2v7yA:
undetectable		 4pooA-2v7yA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 LEU A 164
GLY A 310
LEU A 168
VAL A 289
PHE A 173
 None
ADP  A1505 (-3.1A)
None
None
None
 1.05A 4wnwB-2v7yA:
undetectable		 4wnwB-2v7yA:
22.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 169
GLY A 198
LYS A 239
SER A 243
GLY A 311
SER A 312
ARG A 314
ILE A 315
 ADP  A1505 (-3.4A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
None
ADP  A1505 (-4.8A)
 1.11A 5aqfA-2v7yA:
47.1		 5aqfA-2v7yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 170
GLY A 198
GLU A 236
LYS A 239
SER A 243
GLY A 311
SER A 312
ILE A 315
 ADP  A1505 (-3.5A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.7A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
ADP  A1505 (-4.8A)
 0.55A 5aqfA-2v7yA:
47.1		 5aqfA-2v7yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 GLY A 170
GLY A 198
GLY A 310
SER A 312
ILE A 315
 ADP  A1505 (-3.5A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
ADP  A1505 (-4.8A)
 0.94A 5aqfA-2v7yA:
47.1		 5aqfA-2v7yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 169
GLY A 198
LYS A 239
SER A 243
GLY A 311
SER A 312
ARG A 314
ILE A 315
 ADP  A1505 (-3.4A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
None
ADP  A1505 (-4.8A)
 1.12A 5aqfC-2v7yA:
46.8		 5aqfC-2v7yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 170
GLY A 198
GLU A 236
LYS A 239
SER A 243
GLY A 311
SER A 312
ILE A 315
 ADP  A1505 (-3.5A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.7A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
ADP  A1505 (-4.8A)
 0.54A 5aqfC-2v7yA:
46.8		 5aqfC-2v7yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 169
GLY A 198
LYS A 239
SER A 243
GLY A 311
SER A 312
ARG A 314
ILE A 315
 ADP  A1505 (-3.4A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
None
ADP  A1505 (-4.8A)
 1.11A 5aqyA-2v7yA:
50.1		 5aqyA-2v7yA:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 10 GLY A 170
GLY A 197
GLY A 311
SER A 312
ILE A 315
 ADP  A1505 (-3.5A)
None
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
ADP  A1505 (-4.8A)
 1.01A 5aqyA-2v7yA:
50.1		 5aqyA-2v7yA:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		8 / 10 GLY A 170
GLY A 198
GLU A 236
LYS A 239
SER A 243
GLY A 311
SER A 312
ILE A 315
 ADP  A1505 (-3.5A)
ADP  A1505 (-3.3A)
ADP  A1505 (-3.7A)
ADP  A1505 (-3.0A)
ADP  A1505 (-2.8A)
ADP  A1505 (-3.1A)
ADP  A1505 (-3.5A)
ADP  A1505 (-4.8A)
 0.56A 5aqyA-2v7yA:
50.1		 5aqyA-2v7yA:
38.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 6 ALA A  53
GLN A  56
GLN A 229
ASP A 233
 None
 1.10A 5y9aA-2v7yA:
undetectable		 5y9aA-2v7yA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		3 / 3 LEU A 209
ASP A 224
ILE A  58
 None
 0.65A 6dh0B-2v7yA:
undetectable		 6dh0B-2v7yA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		5 / 12 LEU A   9
ASP A 337
VAL A 340
GLY A 169
PRO A 117
 None
ADP  A1505 ( 4.6A)
None
ADP  A1505 (-3.4A)
PO4  A1506 ( 4.4A)
 0.91A 6dilA-2v7yA:
undetectable		 6dilA-2v7yA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 4 LYS A 188
LEU A 298
ALA A 189
LEU A 293
 None
 1.49A 6gnrA-2v7yA:
undetectable		 6gnrA-2v7yA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 4 LYS A 188
LEU A 298
ALA A 189
LEU A 293
 None
 1.47A 6gnrB-2v7yA:
1.9		 6gnrB-2v7yA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2v7y CHAPERONE PROTEIN
DNAK
(Geobacillus
kaustophilus) 		4 / 7 VAL A 139
ILE A 351
GLY A 154
ARG A 125
 None
 0.85A 6hd6B-2v7yA:
undetectable		 6hd6B-2v7yA:
10.11