SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.83A 1a7yA-2v7zA:
undetectable		 1a7yA-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.85A 1a7yB-2v7zA:
undetectable		 1a7yB-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.75A 1dscC-2v7zA:
undetectable		 1dscC-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.82A 1fjaC-2v7zA:
undetectable		 1fjaC-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.82A 1fjaD-2v7zA:
undetectable		 1fjaD-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 6 ALA A 270
SER A 254
ARG A 301
LEU A 274
 None
 0.92A 1gahA-2v7zA:
undetectable		 1gahA-2v7zA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.81A 1i3wE-2v7zA:
undetectable		 1i3wE-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.83A 1i3wE-2v7zA:
undetectable		 1i3wE-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.84A 1i3wF-2v7zA:
undetectable		 1i3wF-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.85A 1i3wG-2v7zA:
undetectable		 1i3wG-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.84A 1i3wG-2v7zA:
undetectable		 1i3wG-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.82A 1i3wH-2v7zA:
undetectable		 1i3wH-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.83A 1mnvD-2v7zA:
undetectable		 1mnvD-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.81A 1mnvD-2v7zA:
undetectable		 1mnvD-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.82A 1ovfB-2v7zA:
undetectable		 1ovfB-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.83A 1qfiA-2v7zA:
undetectable		 1qfiA-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.82A 1qfiB-2v7zA:
undetectable		 1qfiB-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 LYS A 246
ILE A 291
THR A 295
 None
 0.73A 1rx3A-2v7zA:
undetectable		 1rx3A-2v7zA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.82A 1unjL-2v7zA:
undetectable		 1unjL-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.78A 1unjL-2v7zA:
undetectable		 1unjL-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.85A 1unjR-2v7zA:
undetectable		 1unjR-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.82A 1unjR-2v7zA:
undetectable		 1unjR-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.72A 1unjW-2v7zA:
undetectable		 1unjW-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.81A 1unjX-2v7zA:
undetectable		 1unjX-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.79A 1unjX-2v7zA:
undetectable		 1unjX-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.76A 1unmE-2v7zA:
undetectable		 1unmE-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.72A 1unmE-2v7zA:
undetectable		 1unmE-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  66
PRO A  63
THR A  64
 None
 0.84A 1unmF-2v7zA:
undetectable		 1unmF-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.80A 1unmF-2v7zA:
undetectable		 1unmF-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 THR A  64
THR A  66
PRO A  63
 None
 0.85A 209dC-2v7zA:
undetectable		 209dC-2v7zA:
3.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 6 PHE A 302
ILE A 343
GLY A 230
GLY A 229
 None
ADP  A1383 ( 4.9A)
ADP  A1383 (-3.6A)
None
 0.84A 2qx6A-2v7zA:
undetectable
2qx6B-2v7zA:
undetectable		 2qx6A-2v7zA:
18.38
2qx6B-2v7zA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 7 SER A 120
ALA A 158
ALA A 157
ALA A 161
 None
 0.87A 3a2qA-2v7zA:
undetectable		 3a2qA-2v7zA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 5 VAL A 238
THR A 295
THR A 265
ARG A 264
 None
 1.04A 3bjwA-2v7zA:
undetectable		 3bjwA-2v7zA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 ASN A 168
ASP A 160
GLN A 156
 None
 0.78A 3eeyC-2v7zA:
undetectable		 3eeyC-2v7zA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 ASN A 168
ASP A 160
GLN A 156
 None
 0.77A 3eeyD-2v7zA:
undetectable		 3eeyD-2v7zA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 ASN A 168
ASP A 160
GLN A 156
 None
 0.78A 3eeyE-2v7zA:
undetectable		 3eeyE-2v7zA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 4 PHE A 245
LYS A 246
ILE A 291
THR A 295
 None
 0.65A 3ia4B-2v7zA:
undetectable		 3ia4B-2v7zA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 ARG A  72
ASP A  80
ASP A  86
 None
 0.73A 3jayA-2v7zA:
undetectable		 3jayA-2v7zA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		3 / 3 LYS A 246
ILE A 291
THR A 295
 None
 0.76A 4gh8A-2v7zA:
undetectable		 4gh8A-2v7zA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 ASP A 206
ALA A 180
VAL A 219
SER A 208
THR A 145
 None
 1.29A 4mm6A-2v7zA:
undetectable		 4mm6A-2v7zA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 LEU A  11
ASP A 366
VAL A 369
GLY A 201
PRO A 147
 None
ADP  A1383 ( 4.9A)
None
ADP  A1383 (-3.6A)
None
 1.02A 4njuA-2v7zA:
undetectable		 4njuA-2v7zA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 LEU A  11
ASP A 366
VAL A 369
GLY A 201
PRO A 147
 None
ADP  A1383 ( 4.9A)
None
ADP  A1383 (-3.6A)
None
 1.03A 4njuC-2v7zA:
undetectable		 4njuC-2v7zA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 11 GLY A 229
GLY A 230
GLY A 312
PHE A 198
ILE A 346
 None
ADP  A1383 (-3.6A)
None
None
None
 1.18A 4qoiA-2v7zA:
undetectable
4qoiB-2v7zA:
undetectable		 4qoiA-2v7zA:
18.57
4qoiB-2v7zA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 7 GLU A 175
THR A  13
GLY A  12
THR A  14
 PO4  A1384 (-2.4A)
PO4  A1384 (-4.0A)
PO4  A1384 (-3.3A)
ADP  A1383 (-3.7A)
 0.91A 4qwpB-2v7zA:
undetectable		 4qwpB-2v7zA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 11 SER A 275
ALA A 280
ASP A 234
GLU A 268
GLY A 230
 ADP  A1383 (-2.8A)
None
ADP  A1383 ( 4.5A)
ADP  A1383 (-2.9A)
ADP  A1383 (-3.6A)
 1.44A 4zjoD-2v7zA:
undetectable		 4zjoD-2v7zA:
21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		7 / 10 GLU A 268
LYS A 271
ARG A 272
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 0.80A 5aqfA-2v7zA:
54.5		 5aqfA-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		6 / 10 GLY A 201
LYS A 271
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 1.15A 5aqfA-2v7zA:
54.5		 5aqfA-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		6 / 10 GLY A 201
LYS A 271
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 1.16A 5aqfA-2v7zA:
54.5		 5aqfA-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		9 / 10 GLY A 202
GLY A 230
GLU A 268
LYS A 271
ARG A 272
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-3.6A)
ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 0.60A 5aqfA-2v7zA:
54.5		 5aqfA-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		6 / 10 GLY A 230
GLU A 268
ARG A 272
SER A 275
GLY A 339
SER A 340
 ADP  A1383 (-3.6A)
ADP  A1383 (-2.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
 1.35A 5aqfA-2v7zA:
54.5		 5aqfA-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		7 / 10 GLU A 268
LYS A 271
ARG A 272
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 0.82A 5aqfC-2v7zA:
54.1		 5aqfC-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		7 / 10 GLY A 201
GLY A 230
LYS A 271
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 1.17A 5aqfC-2v7zA:
54.1		 5aqfC-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		6 / 10 GLY A 201
LYS A 271
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 1.17A 5aqfC-2v7zA:
54.1		 5aqfC-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		9 / 10 GLY A 202
GLY A 230
GLU A 268
LYS A 271
ARG A 272
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-3.6A)
ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 0.61A 5aqfC-2v7zA:
54.1		 5aqfC-2v7zA:
99.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		7 / 10 GLU A 268
LYS A 271
ARG A 272
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 0.79A 5aqyA-2v7zA:
57.0		 5aqyA-2v7zA:
63.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		8 / 10 GLY A 201
GLY A 230
LYS A 271
ARG A 272
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 1.15A 5aqyA-2v7zA:
57.0		 5aqyA-2v7zA:
63.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		7 / 10 GLY A 201
LYS A 271
ARG A 272
SER A 275
SER A 340
ARG A 342
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
None
ADP  A1383 ( 4.9A)
 1.20A 5aqyA-2v7zA:
57.0		 5aqyA-2v7zA:
63.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		9 / 10 GLY A 202
GLY A 230
GLU A 268
LYS A 271
ARG A 272
SER A 275
GLY A 339
SER A 340
ILE A 343
 ADP  A1383 (-3.6A)
ADP  A1383 (-3.6A)
ADP  A1383 (-2.9A)
ADP  A1383 (-1.9A)
ADP  A1383 (-4.0A)
ADP  A1383 (-2.8A)
ADP  A1383 (-3.5A)
ADP  A1383 (-3.5A)
ADP  A1383 ( 4.9A)
 0.53A 5aqyA-2v7zA:
57.0		 5aqyA-2v7zA:
63.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 7 ASN A 235
VAL A 238
VAL A 260
ARG A 264
 None
 0.91A 5fpdA-2v7zA:
56.5		 5fpdA-2v7zA:
89.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 7 ASN A 235
VAL A 238
VAL A 260
ARG A 264
 None
 0.92A 5fpdB-2v7zA:
56.4		 5fpdB-2v7zA:
89.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 ALA A 179
ASP A 366
PRO A 365
GLY A 201
THR A  14
 None
ADP  A1383 ( 4.9A)
None
ADP  A1383 (-3.6A)
ADP  A1383 (-3.7A)
 1.33A 5hfjH-2v7zA:
undetectable		 5hfjH-2v7zA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 VAL A 238
ASN A 239
ILE A 242
ALA A 243
LYS A 246
 None
 0.72A 5j2tC-2v7zA:
undetectable		 5j2tC-2v7zA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 GLY A  12
ILE A 197
GLY A 338
ALA A 178
ALA A 179
 PO4  A1384 (-3.3A)
None
ADP  A1383 ( 4.4A)
None
None
 1.08A 6c2mD-2v7zA:
undetectable		 6c2mD-2v7zA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		5 / 12 LEU A  11
ASP A 366
VAL A 369
GLY A 201
PRO A 147
 None
ADP  A1383 ( 4.9A)
None
ADP  A1383 (-3.6A)
None
 1.00A 6dilA-2v7zA:
undetectable		 6dilA-2v7zA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN
(Rattus
norvegicus) 		4 / 7 VAL A  26
ILE A  29
GLY A 166
ALA A 142
 None
 0.83A 6hd6B-2v7zA:
undetectable		 6hd6B-2v7zA:
8.33