SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		4 / 8 ALA A 173
GLY A 169
ALA A 153
ILE A 138
 None
 0.66A 1gtnI-2v82A:
undetectable
1gtnJ-2v82A:
undetectable		 1gtnI-2v82A:
17.13
1gtnJ-2v82A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		5 / 10 SER A 130
ALA A 109
ALA A 114
LEU A 118
LEU A 145
 None
 1.17A 2bxqA-2v82A:
undetectable		 2bxqA-2v82A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		6 / 11 VAL A  93
ASP A  74
ILE A  49
PRO A  50
LEU A  40
ILE A  84
 None
 1.50A 3clbA-2v82A:
undetectable		 3clbA-2v82A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		5 / 12 ALA A  11
LEU A 175
LEU A 162
ILE A  52
GLY A  26
 None
 1.12A 3ozwB-2v82A:
undetectable		 3ozwB-2v82A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		5 / 10 ALA A  60
VAL A  25
ILE A  52
GLY A  63
ALA A  11
 None
 1.05A 3t3cB-2v82A:
undetectable		 3t3cB-2v82A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		6 / 12 VAL A  36
ILE A  38
ALA A  64
VAL A  25
GLY A  26
ILE A  29
 None
 1.30A 5j2tC-2v82A:
undetectable		 5j2tC-2v82A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		5 / 11 THR A  86
SER A  91
ALA A 120
THR A 116
THR A 112
 None
 1.42A 6efnA-2v82A:
7.3		 6efnA-2v82A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2v82 2-DEHYDRO-3-DEOXY-6-
PHOSPHOGALACTONATE
ALDOLASE
(Escherichia
coli) 		3 / 3 THR A  66
GLU A  46
ASN A  41
 KDP  A1207 (-3.6A)
None
None
 0.89A 6nj9K-2v82A:
undetectable		 6nj9K-2v82A:
18.20