SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 6 ILE A 189
ARG A  23
TYR A 186
PHE A 214
 None
 1.37A 1e73M-2v9kA:
undetectable		 1e73M-2v9kA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		5 / 12 TYR A 414
LEU A 476
HIS A 491
ILE A 511
LEU A 514
 EPE  A1534 ( 4.9A)
None
None
None
None
 1.25A 1tw4B-2v9kA:
undetectable		 1tw4B-2v9kA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 6 MET A 250
VAL A 249
LEU A 253
PHE A 261
 None
 1.22A 1x8vA-2v9kA:
undetectable		 1x8vA-2v9kA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		5 / 12 ALA A 416
SER A 415
THR A 497
ILE A 461
PHE A 489
 None
 1.15A 4c49A-2v9kA:
undetectable		 4c49A-2v9kA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 4 THR A 444
ARG A 447
GLU A 488
VAL A 448
 None
CL  A1529 (-3.8A)
CL  A1529 ( 4.9A)
None
 1.36A 4odoC-2v9kA:
0.0		 4odoC-2v9kA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 4 CYH A 112
LEU A 116
LEU A 182
ALA A 185
 ZN  A1533 (-2.3A)
ZN  A1533 ( 4.9A)
None
None
 1.02A 5hpuA-2v9kA:
undetectable
5hpuB-2v9kA:
undetectable		 5hpuA-2v9kA:
4.03
5hpuB-2v9kA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_A_IPHA101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 5 CYH A 230
CYH A 233
HIS A 224
LEU A 226
 None
 1.34A 5hrqA-2v9kA:
undetectable
5hrqB-2v9kA:
undetectable
5hrqF-2v9kA:
undetectable		 5hrqA-2v9kA:
4.03
5hrqB-2v9kA:
5.64
5hrqF-2v9kA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_G_IPHG101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 6 CYH A 230
CYH A 233
HIS A 224
LEU A 226
 None
 1.31A 5hrqD-2v9kA:
undetectable
5hrqG-2v9kA:
undetectable
5hrqH-2v9kA:
undetectable		 5hrqD-2v9kA:
5.64
5hrqG-2v9kA:
4.03
5hrqH-2v9kA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 6 CYH A 230
CYH A 233
HIS A 224
LEU A 226
 None
 1.32A 5hrqH-2v9kA:
undetectable
5hrqK-2v9kA:
undetectable
5hrqL-2v9kA:
undetectable		 5hrqH-2v9kA:
5.64
5hrqK-2v9kA:
4.03
5hrqL-2v9kA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 7 ILE A 418
LEU A 476
MET A 464
LEU A 478
 None
 0.84A 5u4sA-2v9kA:
undetectable		 5u4sA-2v9kA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 6 ARG A 176
VAL A 163
LEU A 174
VAL A  11
 None
 0.89A 5x7zA-2v9kA:
undetectable		 5x7zA-2v9kA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2v9k UNCHARACTERIZED
PROTEIN FLJ32312
(Homo
sapiens) 		4 / 8 LEU A 350
GLY A 351
ARG A 390
TYR A 294
 None
 0.95A 6ce2A-2v9kA:
undetectable		 6ce2A-2v9kA:
12.45