SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.70A 1a7yA-2v9qA:
undetectable		 1a7yA-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.89A 1a7yB-2v9qA:
undetectable		 1a7yB-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.76A 1a7yB-2v9qA:
undetectable		 1a7yB-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.82A 1dscC-2v9qA:
undetectable		 1dscC-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.83A 1fjaC-2v9qA:
undetectable		 1fjaC-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.84A 1fjaD-2v9qA:
undetectable		 1fjaD-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.74A 1i3wE-2v9qA:
undetectable		 1i3wE-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1i3wE-2v9qA:
undetectable		 1i3wE-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1i3wF-2v9qA:
undetectable		 1i3wF-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.75A 1i3wG-2v9qA:
undetectable		 1i3wG-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.78A 1i3wG-2v9qA:
undetectable		 1i3wG-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.76A 1i3wH-2v9qA:
undetectable		 1i3wH-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.75A 1mnvD-2v9qA:
undetectable		 1mnvD-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.70A 1mnvD-2v9qA:
undetectable		 1mnvD-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.74A 1ovfB-2v9qA:
undetectable		 1ovfB-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.69A 1qfiA-2v9qA:
undetectable		 1qfiA-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1qfiB-2v9qA:
undetectable		 1qfiB-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.77A 1unjF-2v9qA:
undetectable		 1unjF-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.75A 1unjF-2v9qA:
undetectable		 1unjF-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.78A 1unjL-2v9qA:
undetectable		 1unjL-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1unjL-2v9qA:
undetectable		 1unjL-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.78A 1unjR-2v9qA:
undetectable		 1unjR-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.75A 1unjR-2v9qA:
undetectable		 1unjR-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.74A 1unjW-2v9qA:
undetectable		 1unjW-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.76A 1unjX-2v9qA:
undetectable		 1unjX-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1unjX-2v9qA:
undetectable		 1unjX-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.76A 1unmE-2v9qA:
undetectable		 1unmE-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.73A 1unmE-2v9qA:
undetectable		 1unmE-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.78A 1unmF-2v9qA:
undetectable		 1unmF-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 228
THR A 230
PRO A 186
 None
 0.76A 1unmF-2v9qA:
undetectable		 1unmF-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 8 LEU A 211
PRO A 176
SER A 251
VAL A 179
 None
 0.92A 2qd2A-2v9qA:
undetectable		 2qd2A-2v9qA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 6 SER A 117
ARG A 131
PHE A 129
ILE A 132
 None
 1.19A 2qeiA-2v9qA:
undetectable		 2qeiA-2v9qA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 GLU A 250
GLY A 242
THR A 243
 None
 0.58A 3iazA-2v9qA:
undetectable		 3iazA-2v9qA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		5 / 9 THR A 110
THR A  86
LEU A 121
LEU A 122
GLY A 125
 None
 1.38A 4c9kA-2v9qA:
undetectable		 4c9kA-2v9qA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		5 / 9 THR A 110
THR A  86
LEU A 121
LEU A 122
GLY A 125
 None
 1.39A 4c9pA-2v9qA:
undetectable		 4c9pA-2v9qA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		3 / 3 THR A 230
PRO A 186
THR A 228
 None
 0.80A 4hivD-2v9qA:
undetectable		 4hivD-2v9qA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 7 LEU A 211
PRO A 176
SER A 251
VAL A 179
 None
 0.99A 4klrA-2v9qA:
undetectable		 4klrA-2v9qA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 5 ILE A  78
ASP A 141
GLU A 164
VAL A 246
 None
 1.20A 4nkxC-2v9qA:
undetectable		 4nkxC-2v9qA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2v9q ROUNDABOUT HOMOLOG 1
(Homo
sapiens) 		4 / 5 ILE A  78
ASP A 141
GLU A 164
VAL A 246
 None
 1.26A 4nkxD-2v9qA:
undetectable		 4nkxD-2v9qA:
17.25