SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.54A 1dvxA-2v9uA:
3.3		 1dvxA-2v9uA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.54A 1dvxB-2v9uA:
undetectable		 1dvxB-2v9uA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.55A 1ictB-2v9uA:
3.2		 1ictB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.54A 1tyrA-2v9uA:
3.6		 1tyrA-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ASP A   3
ASN A   4
THR A  17
 ASP  A   3 ( 0.6A)
ASN  A   4 ( 0.6A)
THR  A  17 ( 0.8A)
 0.60A 2pymB-2v9uA:
undetectable		 2pymB-2v9uA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ASP A   3
ASN A   4
THR A  17
 ASP  A   3 ( 0.6A)
ASN  A   4 ( 0.6A)
THR  A  17 ( 0.8A)
 0.49A 2q63B-2v9uA:
undetectable		 2q63B-2v9uA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.57A 2roxB-2v9uA:
2.9		 2roxB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 SER A 132
LEU A 166
GLY A  60
GLU A  63
 SER  A 132 ( 0.0A)
LEU  A 166 ( 0.5A)
GLY  A  60 ( 0.0A)
GLU  A  63 ( 0.6A)
 0.96A 3aiaA-2v9uA:
undetectable
3aiaB-2v9uA:
undetectable		 3aiaA-2v9uA:
16.51
3aiaB-2v9uA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.54A 3cfqA-2v9uA:
3.3		 3cfqA-2v9uA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.66A 3cfqA-2v9uA:
3.3
3cfqB-2v9uA:
3.2		 3cfqA-2v9uA:
25.56
3cfqB-2v9uA:
25.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.61A 3d2tA-2v9uA:
3.3		 3d2tA-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.66A 3ozkB-2v9uA:
3.4		 3ozkB-2v9uA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.62A 4d7bB-2v9uA:
undetectable		 4d7bB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.67A 4d7bA-2v9uA:
3.2		 4d7bA-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.53A 4i89A-2v9uA:
3.3		 4i89A-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.71A 4ik7B-2v9uA:
3.2		 4ik7B-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.71A 4ikiB-2v9uA:
3.3		 4ikiB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.69A 4ikjA-2v9uA:
3.2
4ikjB-2v9uA:
3.2		 4ikjA-2v9uA:
23.88
4ikjB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		5 / 8 LEU A  62
ALA A 164
LEU A 166
THR A 176
SER A   7
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
SER  A   7 ( 0.0A)
 1.43A 4ikkA-2v9uA:
3.3
4ikkB-2v9uA:
3.2		 4ikkA-2v9uA:
23.88
4ikkB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.67A 4ikkA-2v9uA:
3.3
4ikkB-2v9uA:
3.2		 4ikkA-2v9uA:
23.88
4ikkB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.65A 4iklA-2v9uA:
3.2
4iklB-2v9uA:
3.3		 4iklA-2v9uA:
23.88
4iklB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.67A 4iklA-2v9uA:
3.2
4iklB-2v9uA:
3.3		 4iklA-2v9uA:
23.88
4iklB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 176
THR A 130
HIS A  42
LEU A  25
 THR  A 176 ( 0.8A)
THR  A 130 ( 0.8A)
HIS  A  42 ( 1.0A)
LEU  A  25 ( 0.5A)
 1.30A 4lvcA-2v9uA:
undetectable		 4lvcA-2v9uA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 176
THR A 130
HIS A  42
LEU A  25
 THR  A 176 ( 0.8A)
THR  A 130 ( 0.8A)
HIS  A  42 ( 1.0A)
LEU  A  25 ( 0.5A)
 1.30A 4lvcC-2v9uA:
undetectable		 4lvcC-2v9uA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 SER A  43
ALA A 143
VAL A 142
 SER  A  43 ( 0.0A)
ALA  A 143 ( 0.0A)
VAL  A 142 ( 0.5A)
 0.64A 4o2bC-2v9uA:
undetectable		 4o2bC-2v9uA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.71A 4pwjB-2v9uA:
3.2		 4pwjB-2v9uA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A 152
GLY A 156
GLY A 157
VAL A 158
 THR  A 152 ( 0.8A)
GLY  A 156 ( 0.0A)
GLY  A 157 ( 0.0A)
VAL  A 158 ( 0.6A)
 0.74A 4qvvK-2v9uA:
undetectable
4qvvL-2v9uA:
undetectable		 4qvvK-2v9uA:
22.86
4qvvL-2v9uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A  37
GLY A 156
GLY A 157
VAL A 158
 THR  A  37 ( 0.8A)
GLY  A 156 ( 0.0A)
GLY  A 157 ( 0.0A)
VAL  A 158 ( 0.6A)
 0.85A 4qvvY-2v9uA:
undetectable
4qvvZ-2v9uA:
undetectable		 4qvvY-2v9uA:
22.86
4qvvZ-2v9uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A 152
GLY A 156
GLY A 157
VAL A 158
 THR  A 152 ( 0.8A)
GLY  A 156 ( 0.0A)
GLY  A 157 ( 0.0A)
VAL  A 158 ( 0.6A)
 0.73A 4qvvY-2v9uA:
undetectable
4qvvZ-2v9uA:
undetectable		 4qvvY-2v9uA:
22.86
4qvvZ-2v9uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 SER A  43
ALA A 143
VAL A 142
 SER  A  43 ( 0.0A)
ALA  A 143 ( 0.0A)
VAL  A 142 ( 0.5A)
 0.56A 4x1iA-2v9uA:
undetectable		 4x1iA-2v9uA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.56A 5bojA-2v9uA:
3.2		 5bojA-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.58A 5bojB-2v9uA:
3.1		 5bojB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 SER A  43
ALA A 143
VAL A 142
 SER  A  43 ( 0.0A)
ALA  A 143 ( 0.0A)
VAL  A 142 ( 0.5A)
 0.56A 5eypA-2v9uA:
undetectable		 5eypA-2v9uA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.59A 5l4iA-2v9uA:
3.2		 5l4iA-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A  62
ALA A 164
LEU A 166
THR A 176
 LEU  A  62 ( 0.5A)
ALA  A 164 ( 0.0A)
LEU  A 166 ( 0.5A)
THR  A 176 ( 0.8A)
 0.58A 5l4iB-2v9uA:
3.1		 5l4iB-2v9uA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		3 / 3 SER A  43
ALA A 143
VAL A 142
 SER  A  43 ( 0.0A)
ALA  A 143 ( 0.0A)
VAL  A 142 ( 0.5A)
 0.55A 5xiwC-2v9uA:
undetectable		 5xiwC-2v9uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 176
THR A 130
HIS A  42
LEU A  25
 THR  A 176 ( 0.8A)
THR  A 130 ( 0.8A)
HIS  A  42 ( 1.0A)
LEU  A  25 ( 0.5A)
 1.30A 6gbnA-2v9uA:
undetectable		 6gbnA-2v9uA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 2v9u MSPA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 176
THR A 130
HIS A  42
LEU A  25
 THR  A 176 ( 0.8A)
THR  A 130 ( 0.8A)
HIS  A  42 ( 1.0A)
LEU  A  25 ( 0.5A)
 1.27A 6gbnD-2v9uA:
undetectable		 6gbnD-2v9uA:
16.21