SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2v9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2v9v SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 12 LEU A 432
LEU A 414
MET A 417
ALA A 400
ILE A 387
 None
 0.97A 4x1iD-2v9vA:
undetectable		 4x1iD-2v9vA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2v9v SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 12 LEU A 432
LEU A 414
MET A 417
ALA A 400
ILE A 387
 None
 1.01A 4x1yD-2v9vA:
undetectable		 4x1yD-2v9vA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 2v9v SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 12 LEU A 405
LEU A 414
MET A 417
ALA A 403
ILE A 387
 None
 0.99A 5nm5B-2v9vA:
undetectable		 5nm5B-2v9vA:
18.51