SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2van'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		5 / 11 LEU A 195
TYR A 265
PHE A 200
LEU A 210
PRO A 208
 None
 1.48A 1klmA-2vanA:
3.3		 1klmA-2vanA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		4 / 5 PHE A 278
ARG A 328
ILE A 319
GLU A 316
 None
 1.30A 1oniG-2vanA:
undetectable
1oniH-2vanA:
undetectable		 1oniG-2vanA:
22.44
1oniH-2vanA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		4 / 8 THR A 196
VAL A 269
GLY A 268
VAL A 313
 None
 0.89A 2a1oA-2vanA:
undetectable		 2a1oA-2vanA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		3 / 3 ILE A 255
PHE A 235
HIS A 252
 None
 0.76A 3h0aA-2vanA:
undetectable		 3h0aA-2vanA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		5 / 10 THR A 225
GLY A 237
PHE A 146
LEU A 228
ILE A 138
 None
 1.18A 3kvrA-2vanA:
undetectable		 3kvrA-2vanA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		5 / 10 THR A 225
GLY A 237
PHE A 146
LEU A 228
ILE A 138
 None
 1.28A 3kvrB-2vanA:
undetectable		 3kvrB-2vanA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		4 / 6 GLN A 317
TYR A 327
PRO A 330
LEU A 270
 None
 1.37A 3tgvB-2vanA:
undetectable		 3tgvB-2vanA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		4 / 6 GLN A 317
TYR A 327
PRO A 330
LEU A 270
 None
 1.34A 3tgvD-2vanA:
undetectable		 3tgvD-2vanA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		4 / 5 VAL A 103
ARG A 102
GLU A 147
LEU A 122
 None
 1.37A 4hojA-2vanA:
undetectable		 4hojA-2vanA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2van DNA POLYMERSE BETA
(Rattus
norvegicus) 		3 / 3 ARG A 182
PHE A 320
ARG A 333
 None
 1.22A 5y9yA-2vanA:
undetectable		 5y9yA-2vanA:
22.22