SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.06A 1v55C-2vatA:
undetectable
1v55N-2vatA:
undetectable
1v55P-2vatA:
undetectable		 1v55C-2vatA:
20.27
1v55N-2vatA:
21.62
1v55P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 ASP A  34
GLU A  10
TYR A  39
 None
 0.80A 1wsvA-2vatA:
undetectable		 1wsvA-2vatA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 TRP A 158
ARG A 131
PHE A 161
 None
None
ACT  A1384 (-3.7A)
 1.50A 1zeaH-2vatA:
undetectable
1zeaL-2vatA:
undetectable		 1zeaH-2vatA:
16.14
1zeaL-2vatA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 LYS A 300
ASP A 135
ASP A 126
 None
 0.67A 2br4D-2vatA:
undetectable		 2br4D-2vatA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 GLY A 151
THR A 155
TRP A 158
MET A 150
 None
 1.11A 2o5yH-2vatA:
undetectable
2o5yL-2vatA:
undetectable		 2o5yH-2vatA:
19.09
2o5yL-2vatA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 GLY A 152
THR A 155
TRP A 158
MET A 150
 None
 1.22A 2o5yH-2vatA:
undetectable
2o5yL-2vatA:
undetectable		 2o5yH-2vatA:
19.09
2o5yL-2vatA:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 11 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
 1.04A 2vavA-2vatA:
59.7		 2vavA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 11 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.85A 2vavA-2vatA:
59.7		 2vavA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 11 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.40A 2vavA-2vatA:
59.7		 2vavA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.95A 2vavB-2vatA:
59.3		 2vavB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.81A 2vavB-2vatA:
59.3		 2vavB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
GLN A 281
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.60A 2vavB-2vatA:
59.3		 2vavB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.39A 2vavB-2vatA:
59.3		 2vavB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		7 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 1.00A 2vavC-2vatA:
58.8		 2vavC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.73A 2vavC-2vatA:
58.8		 2vavC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.50A 2vavC-2vatA:
58.8		 2vavC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		7 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.99A 2vavD-2vatA:
58.7		 2vavD-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.74A 2vavD-2vatA:
58.7		 2vavD-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.50A 2vavD-2vatA:
58.7		 2vavD-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
 1.06A 2vavE-2vatA:
59.3		 2vavE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.88A 2vavE-2vatA:
59.3		 2vavE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.58A 2vavE-2vatA:
59.3		 2vavE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.39A 2vavE-2vatA:
59.3		 2vavE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 301
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.84A 2vavF-2vatA:
58.4		 2vavF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
PHE A 301
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
None
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.63A 2vavF-2vatA:
58.4		 2vavF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 301
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 (-2.8A)
 1.42A 2vavF-2vatA:
58.4		 2vavF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 LEU A  59
MET A 150
MET A 367
 None
None
COA  A1383 (-3.6A)
 0.14A 2vavF-2vatA:
58.4		 2vavF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 1.10A 2vavG-2vatA:
58.7		 2vavG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.84A 2vavG-2vatA:
58.7		 2vavG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.63A 2vavG-2vatA:
58.7		 2vavG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.35A 2vavG-2vatA:
58.7		 2vavG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 ( 4.9A)
 1.14A 2vavH-2vatA:
58.8		 2vavH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 LEU A  59
THR A  60
PHE A 186
HIS A 362
VAL A 366
 None
COA  A1383 ( 4.9A)
None
COA  A1383 ( 4.6A)
COA  A1383 ( 4.9A)
 1.40A 2vavH-2vatA:
58.8		 2vavH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 301
HIS A 362
ASP A 363
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
COA  A1383 ( 4.9A)
 0.81A 2vavH-2vatA:
58.8		 2vavH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
PHE A 301
HIS A 362
ASP A 363
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
None
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
COA  A1383 ( 4.9A)
 0.48A 2vavH-2vatA:
58.8		 2vavH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 301
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 (-2.8A)
 1.44A 2vavH-2vatA:
58.8		 2vavH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.81A 2vavI-2vatA:
59.2		 2vavI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
GLN A 281
HIS A 362
ASP A 363
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 (-3.6A)
 0.59A 2vavI-2vatA:
59.2		 2vavI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.39A 2vavI-2vatA:
59.2		 2vavI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.85A 2vavJ-2vatA:
58.2		 2vavJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.66A 2vavJ-2vatA:
58.2		 2vavJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
ASP A 363
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 (-2.8A)
 1.37A 2vavJ-2vatA:
58.2		 2vavJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.90A 2vavK-2vatA:
57.7		 2vavK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.73A 2vavK-2vatA:
57.7		 2vavK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.57A 2vavK-2vatA:
57.7		 2vavK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
PHE A 186
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
None
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.06A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.91A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  58
TYR A 225
LYS A 226
ARG A 234
PHE A 301
 COA  A1383 ( 4.1A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
 1.31A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 THR A  60
PHE A 186
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.9A)
None
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.19A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  60
TYR A 225
LYS A 226
ARG A 234
PHE A 301
HIS A 362
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
None
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.86A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
PHE A 301
HIS A 362
ASP A 363
PHE A 365
VAL A 366
 COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
None
COA  A1383 ( 4.6A)
COA  A1383 (-2.8A)
None
COA  A1383 ( 4.9A)
 0.63A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAV_L_CSCL1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 4 THR A  58
LEU A  59
MET A 150
MET A 367
 COA  A1383 ( 4.1A)
None
None
COA  A1383 (-3.6A)
 0.13A 2vavL-2vatA:
58.3		 2vavL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 1.10A 2vaxA-2vatA:
59.2		 2vaxA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.77A 2vaxA-2vatA:
59.2		 2vaxA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.63A 2vaxA-2vatA:
59.2		 2vaxA-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
ASN A 222
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 ( 4.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.09A 2vaxB-2vatA:
59.0		 2vaxB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.93A 2vaxB-2vatA:
59.0		 2vaxB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ASN A 222
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.27A 2vaxB-2vatA:
59.0		 2vaxB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.64A 2vaxB-2vatA:
59.0		 2vaxB-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		7 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 1.03A 2vaxC-2vatA:
58.6		 2vaxC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.79A 2vaxC-2vatA:
58.6		 2vaxC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.62A 2vaxC-2vatA:
58.6		 2vaxC-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.84A 2vaxD-2vatA:
58.6		 2vaxD-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		11 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.63A 2vaxD-2vatA:
58.6		 2vaxD-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 1.09A 2vaxE-2vatA:
58.9		 2vaxE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.75A 2vaxE-2vatA:
58.9		 2vaxE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.60A 2vaxE-2vatA:
58.9		 2vaxE-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.97A 2vaxF-2vatA:
58.4		 2vaxF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.75A 2vaxF-2vatA:
58.4		 2vaxF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
GLN A 281
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.70A 2vaxF-2vatA:
58.4		 2vaxF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.44A 2vaxF-2vatA:
58.4		 2vaxF-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		7 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 1.03A 2vaxG-2vatA:
58.4		 2vaxG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.70A 2vaxG-2vatA:
58.4		 2vaxG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.59A 2vaxG-2vatA:
58.4		 2vaxG-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.08A 2vaxH-2vatA:
58.5		 2vaxH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.72A 2vaxH-2vatA:
58.5		 2vaxH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.45A 2vaxH-2vatA:
58.5		 2vaxH-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
ASN A 222
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 ( 4.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.12A 2vaxI-2vatA:
58.9		 2vaxI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.94A 2vaxI-2vatA:
58.9		 2vaxI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ASN A 222
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 1.26A 2vaxI-2vatA:
58.9		 2vaxI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_I_CSCI1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.61A 2vaxI-2vatA:
58.9		 2vaxI-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 1.12A 2vaxJ-2vatA:
58.3		 2vaxJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.76A 2vaxJ-2vatA:
58.3		 2vaxJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
MET A 367
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 (-3.6A)
 0.66A 2vaxJ-2vatA:
58.3		 2vaxJ-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.94A 2vaxK-2vatA:
58.3		 2vaxK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.72A 2vaxK-2vatA:
58.3		 2vaxK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		10 / 12 THR A  58
LEU A  59
THR A  60
TYR A 225
LYS A 226
TYR A 277
GLN A 281
HIS A 362
PHE A 365
VAL A 366
 COA  A1383 ( 4.1A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
 0.71A 2vaxK-2vatA:
58.3		 2vaxK-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 ARG A 218
TYR A 225
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 (-3.8A)
COA  A1383 (-4.1A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.90A 2vaxL-2vatA:
58.2		 2vaxL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
ARG A 234
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-3.8A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.74A 2vaxL-2vatA:
58.2		 2vaxL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
GLN A 281
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.0A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.71A 2vaxL-2vatA:
58.2		 2vaxL-2vatA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		9 / 12 THR A  58
THR A  60
TYR A 225
LYS A 226
TYR A 277
HIS A 362
PHE A 365
VAL A 366
MET A 367
 COA  A1383 ( 4.1A)
COA  A1383 ( 4.9A)
COA  A1383 (-4.1A)
COA  A1383 (-2.8A)
COA  A1383 (-4.4A)
COA  A1383 ( 4.6A)
None
COA  A1383 ( 4.9A)
COA  A1383 (-3.6A)
 0.44A 2vaxL-2vatA:
58.2		 2vaxL-2vatA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.00A 2y69C-2vatA:
undetectable
2y69N-2vatA:
undetectable
2y69P-2vatA:
undetectable		 2y69C-2vatA:
20.27
2y69N-2vatA:
21.62
2y69P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 9 VAL A 146
GLY A 147
GLY A 152
ILE A 327
LEU A 326
 None
 0.94A 2z0yA-2vatA:
undetectable		 2z0yA-2vatA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.12A 3ablA-2vatA:
undetectable
3ablC-2vatA:
undetectable
3ablP-2vatA:
undetectable		 3ablA-2vatA:
21.62
3ablC-2vatA:
20.27
3ablP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.09A 3ablC-2vatA:
undetectable
3ablN-2vatA:
undetectable
3ablP-2vatA:
undetectable		 3ablC-2vatA:
20.27
3ablN-2vatA:
21.62
3ablP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.03A 3abmA-2vatA:
undetectable
3abmC-2vatA:
undetectable
3abmP-2vatA:
undetectable		 3abmA-2vatA:
21.62
3abmC-2vatA:
20.27
3abmP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.06A 3asnC-2vatA:
undetectable
3asnN-2vatA:
undetectable
3asnP-2vatA:
2.2		 3asnC-2vatA:
20.27
3asnN-2vatA:
21.62
3asnP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.07A 3asoA-2vatA:
undetectable
3asoC-2vatA:
undetectable
3asoP-2vatA:
undetectable		 3asoA-2vatA:
21.62
3asoC-2vatA:
20.27
3asoP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.06A 3asoC-2vatA:
undetectable
3asoN-2vatA:
undetectable
3asoP-2vatA:
undetectable		 3asoC-2vatA:
20.27
3asoN-2vatA:
21.62
3asoP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 ILE A 123
HIS A 304
PHE A 301
TYR A  91
 None
 0.96A 3b9lA-2vatA:
undetectable		 3b9lA-2vatA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 GLY A 334
TRP A 185
PHE A 186
TYR A 225
 None
None
None
COA  A1383 (-4.1A)
 1.32A 3ccfA-2vatA:
2.8		 3ccfA-2vatA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 6 ILE A  54
TRP A 158
VAL A 127
HIS A 130
 None
None
ACT  A1384 ( 4.7A)
None
 1.47A 3deuA-2vatA:
undetectable		 3deuA-2vatA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 SER A  61
THR A  60
GLY A 151
ILE A 172
VAL A  55
 None
COA  A1383 ( 4.9A)
None
None
None
 0.93A 3fzgA-2vatA:
2.5		 3fzgA-2vatA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ILE A 193
GLY A 213
ARG A 212
ALA A 282
PRO A 197
 None
 1.10A 3jb1A-2vatA:
undetectable		 3jb1A-2vatA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 PHE A 186
ILE A 193
LEU A  59
PHE A 289
 None
 0.73A 3rqwI-2vatA:
undetectable
3rqwJ-2vatA:
undetectable		 3rqwI-2vatA:
20.64
3rqwJ-2vatA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 VAL A  37
HIS A 130
PHE A  24
PRO A 119
 None
 1.29A 3v35A-2vatA:
undetectable		 3v35A-2vatA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 0.99A 3wg7A-2vatA:
undetectable
3wg7C-2vatA:
undetectable
3wg7P-2vatA:
2.1		 3wg7A-2vatA:
21.62
3wg7C-2vatA:
20.27
3wg7P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.02A 3wg7C-2vatA:
undetectable
3wg7N-2vatA:
undetectable
3wg7P-2vatA:
2.1		 3wg7C-2vatA:
20.27
3wg7N-2vatA:
21.62
3wg7P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.03A 3x2qA-2vatA:
undetectable
3x2qC-2vatA:
undetectable
3x2qP-2vatA:
undetectable		 3x2qA-2vatA:
21.62
3x2qC-2vatA:
20.27
3x2qP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.06A 3x2qC-2vatA:
undetectable
3x2qN-2vatA:
undetectable
3x2qP-2vatA:
undetectable		 3x2qC-2vatA:
20.27
3x2qN-2vatA:
21.62
3x2qP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 PRO A  95
ASN A  90
HIS A  57
 None
 1.01A 4ma3H-2vatA:
undetectable
4ma3L-2vatA:
undetectable		 4ma3H-2vatA:
19.87
4ma3L-2vatA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 6 TYR A 225
THR A 298
LEU A  59
GLN A 189
 COA  A1383 (-4.1A)
None
None
None
 1.23A 4qztA-2vatA:
undetectable		 4qztA-2vatA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 4 ALA A 144
VAL A  55
GLY A 151
THR A 155
 None
 1.04A 4ubeA-2vatA:
3.9		 4ubeA-2vatA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 12 ILE A 295
ASP A 290
GLN A 209
ALA A 291
ILE A 193
 None
 1.25A 4uroC-2vatA:
undetectable		 4uroC-2vatA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		3 / 3 GLU A 360
LYS A 226
ASN A 359
 None
COA  A1383 (-2.8A)
None
 1.11A 4y1dA-2vatA:
undetectable
4y1dD-2vatA:
undetectable		 4y1dA-2vatA:
18.49
4y1dD-2vatA:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.01A 5b1aA-2vatA:
undetectable
5b1aC-2vatA:
undetectable
5b1aP-2vatA:
undetectable		 5b1aA-2vatA:
21.62
5b1aC-2vatA:
20.27
5b1aP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.16A 5b1bA-2vatA:
undetectable
5b1bC-2vatA:
undetectable
5b1bP-2vatA:
undetectable		 5b1bA-2vatA:
21.62
5b1bC-2vatA:
20.27
5b1bP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.01A 5b3sA-2vatA:
undetectable
5b3sC-2vatA:
undetectable
5b3sP-2vatA:
undetectable		 5b3sA-2vatA:
21.62
5b3sC-2vatA:
20.27
5b3sP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 6 TYR A 336
ASP A 302
ILE A 123
TYR A 294
 None
 1.03A 5ih0A-2vatA:
undetectable		 5ih0A-2vatA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.09A 5iy5C-2vatA:
undetectable
5iy5N-2vatA:
undetectable
5iy5P-2vatA:
2.2		 5iy5C-2vatA:
20.27
5iy5N-2vatA:
21.62
5iy5P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		5 / 10 VAL A 146
GLY A 147
GLY A 152
ILE A 327
LEU A 326
 None
 0.95A 5vm8B-2vatA:
undetectable		 5vm8B-2vatA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		6 / 12 GLY A 361
VAL A 376
LEU A  72
VAL A 146
SER A 149
ILE A 172
 None
None
None
None
COA  A1383 (-3.5A)
None
 1.25A 5vopA-2vatA:
undetectable		 5vopA-2vatA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.03A 5w97A-2vatA:
undetectable
5w97C-2vatA:
2.1
5w97c-2vatA:
2.1		 5w97A-2vatA:
21.62
5w97C-2vatA:
20.27
5w97c-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.04A 5w97C-2vatA:
2.1
5w97a-2vatA:
undetectable
5w97c-2vatA:
2.1		 5w97C-2vatA:
20.27
5w97a-2vatA:
21.62
5w97c-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.01A 5wauA-2vatA:
undetectable
5wauC-2vatA:
undetectable
5wauc-2vatA:
undetectable		 5wauA-2vatA:
21.62
5wauC-2vatA:
20.27
5wauc-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.03A 5wauC-2vatA:
undetectable
5waua-2vatA:
undetectable
5wauc-2vatA:
undetectable		 5wauC-2vatA:
20.27
5waua-2vatA:
21.62
5wauc-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.08A 5x19A-2vatA:
undetectable
5x19C-2vatA:
undetectable
5x19P-2vatA:
undetectable		 5x19A-2vatA:
21.62
5x19C-2vatA:
20.27
5x19P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.18A 5x1bA-2vatA:
undetectable
5x1bC-2vatA:
undetectable
5x1bP-2vatA:
undetectable		 5x1bA-2vatA:
21.62
5x1bC-2vatA:
20.27
5x1bP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.06A 5x1fA-2vatA:
undetectable
5x1fC-2vatA:
2.2
5x1fP-2vatA:
2.1		 5x1fA-2vatA:
21.62
5x1fC-2vatA:
20.27
5x1fP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 6 GLN A 178
HIS A 154
MET A 297
LEU A  59
 None
 1.26A 5xdhA-2vatA:
undetectable
5xdhC-2vatA:
undetectable		 5xdhA-2vatA:
11.16
5xdhC-2vatA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.02A 5xdqA-2vatA:
undetectable
5xdqC-2vatA:
undetectable
5xdqP-2vatA:
undetectable		 5xdqA-2vatA:
21.62
5xdqC-2vatA:
20.27
5xdqP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.06A 5xdqC-2vatA:
undetectable
5xdqN-2vatA:
undetectable
5xdqP-2vatA:
undetectable		 5xdqC-2vatA:
20.27
5xdqN-2vatA:
21.62
5xdqP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.08A 5xdxC-2vatA:
undetectable
5xdxN-2vatA:
undetectable
5xdxP-2vatA:
undetectable		 5xdxC-2vatA:
20.04
5xdxN-2vatA:
21.62
5xdxP-2vatA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.00A 5z84A-2vatA:
undetectable
5z84C-2vatA:
undetectable
5z84P-2vatA:
undetectable		 5z84A-2vatA:
21.62
5z84C-2vatA:
20.27
5z84P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.05A 5z84C-2vatA:
undetectable
5z84N-2vatA:
undetectable
5z84P-2vatA:
undetectable		 5z84C-2vatA:
20.27
5z84N-2vatA:
21.62
5z84P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 0.97A 5z85A-2vatA:
undetectable
5z85C-2vatA:
undetectable
5z85P-2vatA:
undetectable		 5z85A-2vatA:
21.62
5z85C-2vatA:
20.27
5z85P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 7 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.03A 5z85C-2vatA:
undetectable
5z85N-2vatA:
undetectable
5z85P-2vatA:
undetectable		 5z85C-2vatA:
20.27
5z85N-2vatA:
21.62
5z85P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 0.99A 5z86A-2vatA:
undetectable
5z86C-2vatA:
undetectable
5z86P-2vatA:
undetectable		 5z86A-2vatA:
21.62
5z86C-2vatA:
20.27
5z86P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.05A 5z86C-2vatA:
undetectable
5z86N-2vatA:
undetectable
5z86P-2vatA:
undetectable		 5z86C-2vatA:
20.27
5z86N-2vatA:
21.62
5z86P-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 0.99A 5zcoA-2vatA:
undetectable
5zcoC-2vatA:
undetectable
5zcoP-2vatA:
2.2		 5zcoA-2vatA:
21.62
5zcoC-2vatA:
20.27
5zcoP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.03A 5zcoC-2vatA:
undetectable
5zcoN-2vatA:
undetectable
5zcoP-2vatA:
2.2		 5zcoC-2vatA:
20.27
5zcoN-2vatA:
21.62
5zcoP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.00A 5zcpA-2vatA:
undetectable
5zcpC-2vatA:
undetectable
5zcpP-2vatA:
undetectable		 5zcpA-2vatA:
21.62
5zcpC-2vatA:
20.27
5zcpP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.03A 5zcpC-2vatA:
undetectable
5zcpN-2vatA:
undetectable
5zcpP-2vatA:
undetectable		 5zcpC-2vatA:
20.27
5zcpN-2vatA:
21.62
5zcpP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 HIS A  57
ASP A 290
HIS A 154
LEU A 214
 None
 1.00A 5zcqA-2vatA:
undetectable
5zcqC-2vatA:
undetectable
5zcqP-2vatA:
undetectable		 5zcqA-2vatA:
21.62
5zcqC-2vatA:
20.27
5zcqP-2vatA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 ASP A 126
HIS A  57
ASN A  90
HIS A 130
 None
 1.03A 5zj8A-2vatA:
2.7		 5zj8A-2vatA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 6 TYR A 194
ILE A 193
ALA A 296
ARG A 190
 None
 1.17A 6hu9m-2vatA:
undetectable
6hu9q-2vatA:
undetectable		 6hu9m-2vatA:
22.46
6hu9q-2vatA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE
(Acremonium
chrysogenum) 		4 / 8 LEU A 214
HIS A  57
ASP A 290
HIS A 154
 None
 1.13A 6nknC-2vatA:
undetectable
6nknN-2vatA:
undetectable
6nknP-2vatA:
undetectable		 6nknC-2vatA:
20.27
6nknN-2vatA:
21.62
6nknP-2vatA:
20.27