SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 12 GLU A  63
GLY A  70
ALA A  53
LEU A  48
ASN A 185
 None
 1.28A 1nw3A-2vd2A:
undetectable		 1nw3A-2vd2A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 8 LEU A 203
PHE A 182
MET A   7
THR A   6
LEU A  48
 None
 1.38A 2einA-2vd2A:
undetectable
2einJ-2vd2A:
undetectable		 2einA-2vd2A:
16.70
2einJ-2vd2A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 12 VAL A 207
LEU A  88
GLY A  26
ALA A  25
LEU A  21
 None
 1.09A 3pghA-2vd2A:
undetectable		 3pghA-2vd2A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 12 VAL A 207
LEU A  88
GLY A  26
ALA A  25
LEU A  21
 None
 1.08A 3rr3A-2vd2A:
undetectable		 3rr3A-2vd2A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 12 VAL A 207
LEU A  88
GLY A  26
ALA A  25
LEU A  21
 None
 1.08A 3rr3B-2vd2A:
undetectable		 3rr3B-2vd2A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 11 ILE A 114
ALA A 122
GLU A 128
VAL A 133
PRO A 112
 None
 1.10A 3tmzA-2vd2A:
undetectable		 3tmzA-2vd2A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		4 / 8 ASP A  75
GLY A  73
VAL A  84
SER A 188
 None
 0.92A 4acbB-2vd2A:
undetectable
4acbC-2vd2A:
undetectable		 4acbB-2vd2A:
18.92
4acbC-2vd2A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 9 THR A   6
ILE A  51
GLY A  70
LEU A  22
LEU A  29
 None
 1.22A 4ze0A-2vd2A:
undetectable		 4ze0A-2vd2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		4 / 8 ILE A 135
PHE A 126
GLN A 132
GLU A 131
 None
 0.99A 5dqyA-2vd2A:
undetectable		 5dqyA-2vd2A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.61A 5qglA-2vd2A:
undetectable		 5qglA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.58A 5qguA-2vd2A:
undetectable		 5qguA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.64A 5qgvA-2vd2A:
undetectable		 5qgvA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.64A 5qgwA-2vd2A:
undetectable		 5qgwA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.64A 5qgxA-2vd2A:
undetectable		 5qgxA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.65A 5qh1A-2vd2A:
undetectable		 5qh1A-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.61A 5qh4A-2vd2A:
undetectable		 5qh4A-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.61A 5qh9A-2vd2A:
undetectable		 5qh9A-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.60A 5qhcA-2vd2A:
undetectable		 5qhcA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.59A 5qheA-2vd2A:
undetectable		 5qheA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.62A 5qhfA-2vd2A:
undetectable		 5qhfA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		3 / 3 VAL A 155
VAL A  99
GLN A 129
 None
 0.62A 5qhgA-2vd2A:
undetectable		 5qhgA-2vd2A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 11 MET A   9
ILE A  51
LEU A  22
ILE A 196
MET A 199
 None
 1.33A 6fgcA-2vd2A:
undetectable		 6fgcA-2vd2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_D8ZA831_0
(GEPHYRIN)		 2vd2 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Bacillus
subtilis) 		5 / 11 MET A   9
ILE A  51
LEU A  22
ILE A 196
MET A 199
 None
 1.33A 6fgdA-2vd2A:
undetectable		 6fgdA-2vd2A:
19.91