SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vd3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 GLY A  67
LEU A  87
ILE A 205
ILE A   3
LEU A 201
 None
 1.22A 1kyvA-2vd3A:
2.8
1kyvE-2vd3A:
undetectable		 1kyvA-2vd3A:
23.05
1kyvE-2vd3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ILE A   3
LEU A 201
GLY A  67
LEU A  87
ILE A 205
 None
 1.21A 1kyvB-2vd3A:
undetectable
1kyvC-2vd3A:
undetectable		 1kyvB-2vd3A:
23.05
1kyvC-2vd3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ILE A   3
LEU A 201
GLY A  67
LEU A  87
ILE A 205
 None
 1.22A 1kyvC-2vd3A:
undetectable
1kyvD-2vd3A:
2.7		 1kyvC-2vd3A:
23.05
1kyvD-2vd3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ILE A   3
LEU A 201
GLY A  67
LEU A  87
ILE A 205
 None
 1.22A 1kyvD-2vd3A:
2.7
1kyvE-2vd3A:
undetectable		 1kyvD-2vd3A:
23.05
1kyvE-2vd3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ALA A 147
ILE A 156
VAL A 115
ALA A 114
LEU A 128
 None
None
MRD  A1299 ( 4.4A)
None
None
 1.31A 1udtA-2vd3A:
undetectable		 1udtA-2vd3A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 GLY A 204
GLY A 207
VAL A  26
LEU A 201
ILE A   5
 None
 0.98A 1zq9B-2vd3A:
undetectable		 1zq9B-2vd3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A 172
GLY A 106
PRO A 107
 None
 0.51A 2hreD-2vd3A:
undetectable		 2hreD-2vd3A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 9 LEU A  66
VAL A   7
ILE A  18
GLY A  27
ILE A   5
 None
None
None
MG  A1296 (-3.5A)
None
 1.11A 3ekqB-2vd3A:
undetectable		 3ekqB-2vd3A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 THR A 157
THR A 144
ILE A 104
ILE A 110
LEU A 171
 CL  A1293 (-4.0A)
CL  A1293 ( 3.9A)
None
None
None
 1.32A 3gwxA-2vd3A:
undetectable		 3gwxA-2vd3A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ARG A 275
LEU A 219
ASP A 222
ARG A 223
GLU A 243
 None
 1.46A 3k39C-2vd3A:
undetectable		 3k39C-2vd3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ARG A 275
LEU A 219
ASP A 222
ARG A 223
GLU A 243
 None
 1.43A 3k39I-2vd3A:
undetectable		 3k39I-2vd3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ARG A 275
LEU A 219
ASP A 222
ARG A 223
GLU A 243
 None
 1.45A 3k39J-2vd3A:
undetectable		 3k39J-2vd3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ARG A 275
LEU A 219
ASP A 222
ARG A 223
GLU A 243
 None
 1.44A 3k39K-2vd3A:
undetectable		 3k39K-2vd3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ARG A 275
LEU A 219
ASP A 222
ARG A 223
GLU A 243
 None
 1.45A 3k39L-2vd3A:
undetectable		 3k39L-2vd3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 9 ALA A 114
ASP A 134
ILE A 133
ILE A 156
ILE A 110
 None
IMD  A1288 (-3.8A)
None
None
None
 0.96A 3nu4A-2vd3A:
undetectable		 3nu4A-2vd3A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 9 ALA A 114
ASP A 134
ILE A 133
ILE A 156
ILE A 110
 None
IMD  A1288 (-3.8A)
None
None
None
 0.97A 3s43A-2vd3A:
undetectable		 3s43A-2vd3A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 9 ALA A 153
ILE A 174
ILE A 104
ILE A 110
ALA A 117
 None
 1.01A 5nunA-2vd3A:
undetectable		 5nunA-2vd3A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 LEU A 159
ASP A 158
ALA A  97
LEU A 155
 None
MG  A1294 (-2.9A)
None
None
 1.05A 5nwvA-2vd3A:
undetectable		 5nwvA-2vd3A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 ILE A 266
LEU A 265
MET A 233
LEU A 232
 None
 0.97A 5u4sA-2vd3A:
undetectable		 5u4sA-2vd3A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLY A 142
THR A 144
GLU A 145
 None
CL  A1293 ( 3.9A)
None
 0.66A 6b58A-2vd3A:
undetectable		 6b58A-2vd3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 ASP A  65
ASN A 187
ALA A 186
GLU A 199
 MPD  A1300 (-2.7A)
None
None
None
 1.00A 6ci6A-2vd3A:
undetectable		 6ci6A-2vd3A:
15.68