SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 203
GLY A 207
HIS A 208
ILE A 209
 None
 0.92A 1xf1A-2vd5A:
undetectable		 1xf1A-2vd5A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		8 / 12 VAL A  85
LYS A 100
ASP A 155
THR A 158
ASN A 200
LEU A 202
ALA A 212
ASP A 213
 BI8  A1417 ( 4.7A)
BI8  A1417 (-4.2A)
None
None
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.82A 2eufB-2vd5A:
25.3		 2eufB-2vd5A:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 VAL A 186
VAL A 192
ASP A 199
 None
 0.75A 2fumD-2vd5A:
23.2		 2fumD-2vd5A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 VAL A  85
ALA A  98
GLU A 119
GLY A 154
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
None
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.71A 2hyyA-2vd5A:
19.7		 2hyyA-2vd5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 VAL A  85
ALA A  98
LYS A 100
GLU A 119
TYR A 150
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.73A 2oiqA-2vd5A:
20.2		 2oiqA-2vd5A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 VAL A  85
ALA A  98
LYS A 100
GLU A 119
TYR A 150
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.78A 2pl0A-2vd5A:
20.1		 2pl0A-2vd5A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 183
TRP A 344
GLY A 329
GLY A 326
 None
 0.78A 2qx6A-2vd5A:
undetectable
2qx6B-2vd5A:
undetectable		 2qx6A-2vd5A:
20.71
2qx6B-2vd5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ASP A 204
TYR A 151
PHE A 354
LEU A 159
 None
BI8  A1417 (-4.9A)
None
None
 1.09A 2w98A-2vd5A:
undetectable
2w98B-2vd5A:
undetectable		 2w98A-2vd5A:
21.78
2w98B-2vd5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 GLY A  78
VAL A  85
ALA A  98
TYR A 150
ALA A 212
ASP A 213
 BI8  A1417 ( 3.9A)
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.48A 2wgjA-2vd5A:
20.3		 2wgjA-2vd5A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 ILE A 183
HIS A 187
ARG A 324
GLY A 326
 None
 0.91A 3b9lA-2vd5A:
undetectable		 3b9lA-2vd5A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 5 ILE A 183
HIS A 187
ARG A 324
GLY A 326
 None
 1.10A 3b9mA-2vd5A:
undetectable		 3b9mA-2vd5A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 11 VAL A  85
ALA A  98
TYR A 150
GLY A 154
ASP A 155
LEU A 202
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.8A)
None
None
BI8  A1417 (-4.8A)
 0.66A 3g0fA-2vd5A:
20.1		 3g0fA-2vd5A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		5 / 10 ILE A 196
PHE A 339
ALA A 172
LEU A 176
ALA A 177
 None
 1.43A 3lw5B-2vd5A:
undetectable		 3lw5B-2vd5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 VAL A  85
ALA A  98
GLU A 119
LEU A 123
TYR A 150
HIS A 193
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
None
BI8  A1417 (-4.8A)
None
BI8  A1417 ( 4.1A)
 0.84A 3rgfA-2vd5A:
21.2		 3rgfA-2vd5A:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 179
LEU A 264
PHE A 333
GLY A 329
 None
 1.02A 3sj1X-2vd5A:
undetectable		 3sj1X-2vd5A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 VAL A  85
ALA A  98
GLU A 119
TYR A 150
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.77A 4bkjA-2vd5A:
14.0		 4bkjA-2vd5A:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 ALA A  98
GLU A 119
LEU A 123
HIS A 193
LEU A 202
ALA A 212
ASP A 213
 BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
None
None
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 1.05A 4c8bA-2vd5A:
21.4		 4c8bA-2vd5A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 ALA A  98
LYS A 100
GLU A 119
LEU A 123
ILE A 131
LEU A 202
ALA A 212
 BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 ( 4.9A)
None
None
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.79A 4c8bB-2vd5A:
21.4		 4c8bB-2vd5A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 ALA A  98
LYS A 100
LEU A 123
ILE A 131
HIS A 193
LEU A 202
ALA A 212
 BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
None
None
None
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.68A 4c8bB-2vd5A:
21.4		 4c8bB-2vd5A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 129
ARG A 210
TRP A 130
 None
 1.42A 4cpzC-2vd5A:
undetectable		 4cpzC-2vd5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 129
ARG A 210
TRP A 130
 None
 1.49A 4cpzE-2vd5A:
undetectable		 4cpzE-2vd5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 129
ARG A 210
TRP A 130
 None
 1.49A 4cpzF-2vd5A:
undetectable		 4cpzF-2vd5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 129
ARG A 210
TRP A 130
 None
 1.49A 4cpzG-2vd5A:
undetectable		 4cpzG-2vd5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 VAL A  85
ALA A  98
ASP A 155
ASP A 195
ASN A 200
LEU A 202
ASP A 213
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
None
None
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.75A 4i41A-2vd5A:
26.9		 4i41A-2vd5A:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 12 GLY A  78
VAL A  85
ALA A  98
LEU A 134
LEU A 146
GLY A 154
LEU A 202
 BI8  A1417 ( 3.9A)
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
None
None
None
BI8  A1417 (-4.8A)
 0.64A 4ifgA-2vd5A:
23.4		 4ifgA-2vd5A:
26.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 ARG A 324
ASP A 332
LEU A 325
ASP A 312
 None
 1.04A 4k0bA-2vd5A:
undetectable		 4k0bA-2vd5A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 7 VAL A  85
ALA A  98
ASP A 155
LEU A 202
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
None
BI8  A1417 (-4.8A)
 0.80A 4l9iA-2vd5A:
9.6		 4l9iA-2vd5A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 7 VAL A  85
ALA A  98
MET A 148
LEU A 202
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
 0.79A 4l9iA-2vd5A:
9.6		 4l9iA-2vd5A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		5 / 8 GLY A  80
VAL A  85
ALA A  98
LYS A 100
MET A 148
 None
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 (-4.1A)
 0.72A 4l9iB-2vd5A:
31.6		 4l9iB-2vd5A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		5 / 9 SER A 379
GLY A 380
TYR A 143
ASP A 387
GLY A 381
 None
 1.34A 4lb0A-2vd5A:
undetectable		 4lb0A-2vd5A:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		8 / 12 VAL A  85
ALA A  98
LYS A 100
MET A 148
TYR A 150
LEU A 202
ALA A 212
ASP A 213
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.77A 4mxyB-2vd5A:
22.0		 4mxyB-2vd5A:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		8 / 12 VAL A  85
ALA A  98
LYS A 100
MET A 148
TYR A 150
LEU A 202
ALA A 212
ASP A 213
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.77A 4mxzB-2vd5A:
22.0		 4mxzB-2vd5A:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		5 / 8 ILE A  77
VAL A  85
ALA A  98
ASN A 200
LEU A 202
 BI8  A1417 (-4.1A)
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
 0.58A 4ogrA-2vd5A:
25.7		 4ogrA-2vd5A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		5 / 7 ALA A  98
ASP A 155
ASN A 200
LEU A 202
ASP A 213
 BI8  A1417 ( 3.8A)
None
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.70A 4ogrE-2vd5A:
25.4		 4ogrE-2vd5A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 9 ILE A  77
VAL A  85
ALA A  98
ASN A 200
LEU A 202
ASP A 213
 BI8  A1417 (-4.1A)
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.78A 4ogrI-2vd5A:
25.6		 4ogrI-2vd5A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		10 / 12 ILE A  77
ALA A  98
LYS A 100
GLU A 119
THR A 132
MET A 148
TYR A 150
LEU A 202
ALA A 212
ASP A 213
 BI8  A1417 (-4.1A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.65A 4qmnA-2vd5A:
28.3		 4qmnA-2vd5A:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 11 ILE A  77
ALA A  98
GLU A 119
MET A 148
TYR A 150
LEU A 202
ASP A 213
 BI8  A1417 (-4.1A)
BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.60A 4qmsA-2vd5A:
28.4		 4qmsA-2vd5A:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMS_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		7 / 11 ILE A  77
ALA A  98
LYS A 100
MET A 148
TYR A 150
LEU A 202
ASP A 213
 BI8  A1417 (-4.1A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.89A 4qmsA-2vd5A:
28.4		 4qmsA-2vd5A:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		8 / 12 ILE A  77
GLY A  78
VAL A  85
ALA A  98
THR A 132
MET A 148
TYR A 150
LEU A 202
 BI8  A1417 (-4.1A)
BI8  A1417 ( 3.9A)
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.1A)
BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
 0.64A 4qmzA-2vd5A:
28.1		 4qmzA-2vd5A:
26.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 VAL A  85
LYS A 100
HIS A 193
LEU A 202
 BI8  A1417 ( 4.7A)
BI8  A1417 (-4.2A)
None
BI8  A1417 (-4.8A)
 0.63A 4qrcA-2vd5A:
20.7		 4qrcA-2vd5A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		8 / 11 GLY A  80
VAL A  85
ALA A  98
TYR A 150
ASN A 200
LEU A 202
ALA A 212
ASP A 213
 None
BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.6A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
BI8  A1417 (-3.8A)
 0.62A 4u5jA-2vd5A:
23.1		 4u5jA-2vd5A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ALA A 376
THR A 375
VAL A 378
VAL A  76
 None
 0.84A 5eckA-2vd5A:
undetectable		 5eckA-2vd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ALA A 376
THR A 375
VAL A 378
VAL A  76
 None
 0.90A 5eckD-2vd5A:
undetectable		 5eckD-2vd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ALA A 376
THR A 375
VAL A 378
VAL A  76
 None
 0.91A 5eclA-2vd5A:
undetectable		 5eclA-2vd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 ALA A 376
THR A 375
VAL A 378
VAL A  76
 None
 0.82A 5eclD-2vd5A:
undetectable		 5eclD-2vd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 ALA A 376
THR A 375
VAL A 378
VAL A  76
 None
 0.87A 5ecnD-2vd5A:
undetectable		 5ecnD-2vd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 7 GLY A  80
LEU A 134
ASP A 213
PHE A 214
 None
None
BI8  A1417 (-3.8A)
None
 0.89A 5hieB-2vd5A:
21.1		 5hieB-2vd5A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 VAL A  85
ALA A  98
ASP A 155
THR A 158
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
None
None
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.79A 5l2tA-2vd5A:
5.3		 5l2tA-2vd5A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 ALA A  98
GLU A 119
LEU A 202
ASP A 213
 BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.45A 5owrA-2vd5A:
21.4		 5owrA-2vd5A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 325
ARG A 316
LEU A 264
ILE A 314
 None
 0.93A 5v0vA-2vd5A:
3.2		 5v0vA-2vd5A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 VAL A  85
ALA A  98
GLU A 119
TYR A 150
GLY A 154
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
None
BI8  A1417 ( 4.1A)
 0.77A 5zv2A-2vd5A:
19.5		 5zv2A-2vd5A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 LYS A 100
LEU A 202
ASP A 213
 BI8  A1417 (-4.2A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.94A 5zv2A-2vd5A:
19.6		 5zv2A-2vd5A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		3 / 3 TYR A 150
LEU A 202
ASP A 213
 BI8  A1417 (-4.8A)
BI8  A1417 (-4.8A)
BI8  A1417 (-3.8A)
 0.84A 5zv2B-2vd5A:
19.6		 5zv2B-2vd5A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		6 / 12 VAL A  85
ALA A  98
LYS A 100
GLU A 119
LEU A 202
ALA A 212
 BI8  A1417 ( 4.7A)
BI8  A1417 ( 3.8A)
BI8  A1417 (-4.2A)
BI8  A1417 ( 4.9A)
BI8  A1417 (-4.8A)
BI8  A1417 ( 4.1A)
 0.59A 6hd4A-2vd5A:
19.3		 6hd4A-2vd5A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 8 TYR A 143
ILE A 101
ALA A 376
ASP A 387
 None
 1.02A 6hu9a-2vd5A:
undetectable
6hu9e-2vd5A:
2.6		 6hu9a-2vd5A:
22.08
6hu9e-2vd5A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2vd5 DMPK PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 143
ILE A 101
ALA A 376
ASP A 387
 None
 1.03A 6hu9m-2vd5A:
undetectable
6hu9q-2vd5A:
2.6		 6hu9m-2vd5A:
22.08
6hu9q-2vd5A:
16.09