SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vda'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 509
THR A 178
VAL A 131
 None
 0.90A 1hxbA-2vdaA:
undetectable		 1hxbA-2vdaA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 1k2tA-2vdaA:
3.6
1k2tB-2vdaA:
undetectable		 1k2tA-2vdaA:
18.68
1k2tB-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 1k2tA-2vdaA:
3.6
1k2tB-2vdaA:
undetectable		 1k2tA-2vdaA:
18.68
1k2tB-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.46A 1lzzA-2vdaA:
undetectable
1lzzB-2vdaA:
undetectable		 1lzzA-2vdaA:
18.68
1lzzB-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 1m00A-2vdaA:
undetectable
1m00B-2vdaA:
undetectable		 1m00A-2vdaA:
18.68
1m00B-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 1m00A-2vdaA:
undetectable
1m00B-2vdaA:
undetectable		 1m00A-2vdaA:
18.68
1m00B-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.47A 1p6jA-2vdaA:
undetectable
1p6jB-2vdaA:
undetectable		 1p6jA-2vdaA:
18.68
1p6jB-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 1p6jA-2vdaA:
undetectable
1p6jB-2vdaA:
undetectable		 1p6jA-2vdaA:
18.68
1p6jB-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.47A 1rs7A-2vdaA:
undetectable
1rs7B-2vdaA:
undetectable		 1rs7A-2vdaA:
18.68
1rs7B-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 1rs7A-2vdaA:
undetectable
1rs7B-2vdaA:
undetectable		 1rs7A-2vdaA:
18.68
1rs7B-2vdaA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 10 GLY A 573
ASP A 568
ILE A 567
GLY A 455
ALA A 507
 None
 1.05A 1sh9B-2vdaA:
undetectable		 1sh9B-2vdaA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 10 ARG A 509
THR A 130
THR A 391
VAL A 211
GLU A 210
 None
 1.39A 1z35A-2vdaA:
undetectable		 1z35A-2vdaA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 8 VAL A 208
VAL A 211
LEU A 207
ASP A 212
 None
 0.85A 2ddwA-2vdaA:
undetectable		 2ddwA-2vdaA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 2g6kA-2vdaA:
undetectable
2g6kB-2vdaA:
undetectable		 2g6kA-2vdaA:
20.58
2g6kB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 2hx4A-2vdaA:
undetectable
2hx4B-2vdaA:
undetectable		 2hx4A-2vdaA:
20.58
2hx4B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 ALA A 136
THR A 130
ALA A 206
PHE A 381
TYR A 380
 None
 1.16A 2nyrA-2vdaA:
2.3		 2nyrA-2vdaA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 509
THR A 178
VAL A 131
 None
 0.76A 2q64A-2vdaA:
undetectable		 2q64A-2vdaA:
8.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 10 GLU A 763
ILE A 676
ARG A 760
ILE A 823
GLU A 751
 None
 1.31A 2qeoB-2vdaA:
0.0		 2qeoB-2vdaA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 656
GLU A 647
SER A 374
 None
 0.79A 2xkkA-2vdaA:
1.7
2xkkC-2vdaA:
undetectable		 2xkkA-2vdaA:
23.12
2xkkC-2vdaA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 TYR A 384
TYR A 380
TYR A 182
ILE A 214
 None
 1.50A 2xz5A-2vdaA:
0.0
2xz5B-2vdaA:
0.0		 2xz5A-2vdaA:
13.15
2xz5B-2vdaA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 TYR A 384
VAL A 128
TYR A 380
TYR A 182
 None
 1.34A 2xz5D-2vdaA:
undetectable
2xz5E-2vdaA:
undetectable		 2xz5D-2vdaA:
13.15
2xz5E-2vdaA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 TYR A 326
VAL A 357
THR A 321
 None
 0.87A 2ygnA-2vdaA:
undetectable		 2ygnA-2vdaA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3b3nA-2vdaA:
undetectable
3b3nB-2vdaA:
undetectable		 3b3nA-2vdaA:
20.58
3b3nB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3b3oA-2vdaA:
undetectable
3b3oB-2vdaA:
undetectable		 3b3oA-2vdaA:
20.58
3b3oB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 8 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.38A 3b3pA-2vdaA:
undetectable
3b3pB-2vdaA:
undetectable		 3b3pA-2vdaA:
20.58
3b3pB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 GLY A 573
GLY A 576
ILE A 556
ASP A 422
THR A 414
 None
 1.19A 3ckkA-2vdaA:
undetectable		 3ckkA-2vdaA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 ARG A 656
ILE A 659
TRP A 775
HIS A 778
 None
 0.95A 3deuA-2vdaA:
0.2		 3deuA-2vdaA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 5 ASN A 143
ALA A 120
GLY A 155
THR A 178
 None
 0.93A 3dl9A-2vdaA:
undetectable		 3dl9A-2vdaA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 ILE A  99
GLY A 389
ALA A 112
ALA A 206
VAL A 211
 None
 0.88A 3jb2A-2vdaA:
undetectable		 3jb2A-2vdaA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 ILE A  99
GLY A 389
ALA A 112
ALA A 206
VAL A 211
 None
 0.92A 3jb3A-2vdaA:
undetectable		 3jb3A-2vdaA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3jt3A-2vdaA:
undetectable
3jt3B-2vdaA:
undetectable		 3jt3A-2vdaA:
20.58
3jt3B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3jt5A-2vdaA:
undetectable
3jt5B-2vdaA:
undetectable		 3jt5A-2vdaA:
20.58
3jt5B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3jt7A-2vdaA:
undetectable
3jt7B-2vdaA:
undetectable		 3jt7A-2vdaA:
20.58
3jt7B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3jt8A-2vdaA:
undetectable
3jt8B-2vdaA:
undetectable		 3jt8A-2vdaA:
20.58
3jt8B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 8 LEU A 774
THR A 770
GLY A 765
THR A 675
ILE A 679
 None
 1.42A 3jusB-2vdaA:
0.0		 3jusB-2vdaA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 9 LEU A 774
THR A 770
GLY A 765
THR A 675
ILE A 679
 None
 1.42A 3jusB-2vdaA:
0.0		 3jusB-2vdaA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3jwsA-2vdaA:
undetectable
3jwsB-2vdaA:
undetectable		 3jwsA-2vdaA:
20.58
3jwsB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 3jwtA-2vdaA:
1.7
3jwtB-2vdaA:
undetectable		 3jwtA-2vdaA:
20.58
3jwtB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3jwuA-2vdaA:
undetectable
3jwuB-2vdaA:
undetectable		 3jwuA-2vdaA:
20.58
3jwuB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3jwvA-2vdaA:
undetectable
3jwvB-2vdaA:
undetectable		 3jwvA-2vdaA:
20.58
3jwvB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 LEU A 387
VAL A 211
VAL A 129
PHE A 401
LEU A 407
 None
 1.45A 3meeA-2vdaA:
undetectable		 3meeA-2vdaA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3n2rA-2vdaA:
undetectable
3n2rB-2vdaA:
undetectable		 3n2rA-2vdaA:
20.58
3n2rB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 3n5vA-2vdaA:
undetectable
3n5vB-2vdaA:
undetectable		 3n5vA-2vdaA:
20.58
3n5vB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3n5yA-2vdaA:
undetectable
3n5yB-2vdaA:
undetectable		 3n5yA-2vdaA:
20.58
3n5yB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 3nlkA-2vdaA:
undetectable
3nlkB-2vdaA:
undetectable		 3nlkA-2vdaA:
20.58
3nlkB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 3nlkA-2vdaA:
undetectable
3nlkB-2vdaA:
undetectable		 3nlkA-2vdaA:
20.58
3nlkB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 3nlmA-2vdaA:
undetectable
3nlmB-2vdaA:
undetectable		 3nlmA-2vdaA:
20.58
3nlmB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3nlnA-2vdaA:
undetectable
3nlnB-2vdaA:
undetectable		 3nlnA-2vdaA:
20.58
3nlnB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3nlvA-2vdaA:
undetectable
3nlvB-2vdaA:
undetectable		 3nlvA-2vdaA:
20.58
3nlvB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3nlwA-2vdaA:
undetectable
3nlwB-2vdaA:
undetectable		 3nlwA-2vdaA:
20.58
3nlwB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 3nlxA-2vdaA:
undetectable
3nlxB-2vdaA:
undetectable		 3nlxA-2vdaA:
20.58
3nlxB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3nm0A-2vdaA:
3.6
3nm0B-2vdaA:
undetectable		 3nm0A-2vdaA:
20.58
3nm0B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 3nnyA-2vdaA:
undetectable
3nnyB-2vdaA:
1.1		 3nnyA-2vdaA:
20.58
3nnyB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3pneA-2vdaA:
3.5
3pneB-2vdaA:
undetectable		 3pneA-2vdaA:
20.58
3pneB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3pngA-2vdaA:
undetectable
3pngB-2vdaA:
undetectable		 3pngA-2vdaA:
20.58
3pngB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 3rqjA-2vdaA:
undetectable
3rqjB-2vdaA:
undetectable		 3rqjA-2vdaA:
20.58
3rqjB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 3rqlA-2vdaA:
3.6
3rqlB-2vdaA:
undetectable		 3rqlA-2vdaA:
20.58
3rqlB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3rqmA-2vdaA:
undetectable
3rqmB-2vdaA:
undetectable		 3rqmA-2vdaA:
20.58
3rqmB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.50A 3rqnA-2vdaA:
1.5
3rqnB-2vdaA:
undetectable		 3rqnA-2vdaA:
20.58
3rqnB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3rqnA-2vdaA:
1.5
3rqnB-2vdaA:
undetectable		 3rqnA-2vdaA:
20.58
3rqnB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 GLY A 582
GLY A 576
ARG A 416
VAL A 548
ALA A 547
 None
 1.09A 3t7vA-2vdaA:
undetectable		 3t7vA-2vdaA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 3tylA-2vdaA:
undetectable
3tylB-2vdaA:
undetectable		 3tylA-2vdaA:
20.58
3tylB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 3tymA-2vdaA:
1.8
3tymB-2vdaA:
undetectable		 3tymA-2vdaA:
20.58
3tymB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.50A 3tynA-2vdaA:
undetectable
3tynB-2vdaA:
undetectable		 3tynA-2vdaA:
20.58
3tynB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 3tynA-2vdaA:
undetectable
3tynB-2vdaA:
undetectable		 3tynA-2vdaA:
20.58
3tynB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 3tyoA-2vdaA:
undetectable
3tyoB-2vdaA:
undetectable		 3tyoA-2vdaA:
20.58
3tyoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 3tyoA-2vdaA:
undetectable
3tyoB-2vdaA:
undetectable		 3tyoA-2vdaA:
20.58
3tyoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 PHE A 684
SER A 827
SER A 824
 None
 0.97A 3ufgB-2vdaA:
undetectable		 3ufgB-2vdaA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 3ufoA-2vdaA:
undetectable
3ufoB-2vdaA:
undetectable		 3ufoA-2vdaA:
20.58
3ufoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 3ufpA-2vdaA:
undetectable
3ufpB-2vdaA:
3.6		 3ufpA-2vdaA:
20.58
3ufpB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3ufrA-2vdaA:
undetectable
3ufrB-2vdaA:
undetectable		 3ufrA-2vdaA:
20.58
3ufrB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 3ufsA-2vdaA:
undetectable
3ufsB-2vdaA:
undetectable		 3ufsA-2vdaA:
20.58
3ufsB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.41A 3uftA-2vdaA:
undetectable
3uftB-2vdaA:
undetectable		 3uftA-2vdaA:
20.58
3uftB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 3ufuA-2vdaA:
undetectable
3ufuB-2vdaA:
undetectable		 3ufuA-2vdaA:
20.58
3ufuB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 2vda MALTOPORIN
TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 ASN A 369
HIS A 354
GLY A 352
ALA B  19
GLY B  20
 None
 1.24A 3v3oB-2vdaA:
undetectable		 3v3oB-2vdaA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 382
ARG A 656
ASP A 654
 None
 0.95A 3wipG-2vdaA:
undetectable
3wipH-2vdaA:
undetectable		 3wipG-2vdaA:
15.38
3wipH-2vdaA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 4camA-2vdaA:
undetectable
4camB-2vdaA:
undetectable		 4camA-2vdaA:
20.58
4camB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4caoA-2vdaA:
undetectable
4caoB-2vdaA:
undetectable		 4caoA-2vdaA:
20.58
4caoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4caqA-2vdaA:
undetectable
4caqB-2vdaA:
undetectable		 4caqA-2vdaA:
20.58
4caqB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 4cdtA-2vdaA:
undetectable
4cdtB-2vdaA:
undetectable		 4cdtA-2vdaA:
20.58
4cdtB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.45A 4ctrA-2vdaA:
undetectable
4ctrB-2vdaA:
undetectable		 4ctrA-2vdaA:
20.58
4ctrB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 4cttA-2vdaA:
undetectable
4cttB-2vdaA:
undetectable		 4cttA-2vdaA:
20.58
4cttB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.46A 4ctxA-2vdaA:
undetectable
4ctxB-2vdaA:
undetectable		 4ctxA-2vdaA:
20.58
4ctxB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 4cx5A-2vdaA:
undetectable
4cx5B-2vdaA:
undetectable		 4cx5A-2vdaA:
20.71
4cx5B-2vdaA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4d2yA-2vdaA:
undetectable
4d2yB-2vdaA:
undetectable		 4d2yA-2vdaA:
20.58
4d2yB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 4d2zA-2vdaA:
undetectable
4d2zB-2vdaA:
undetectable		 4d2zA-2vdaA:
20.58
4d2zB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.44A 4d30A-2vdaA:
undetectable
4d30B-2vdaA:
undetectable		 4d30A-2vdaA:
20.58
4d30B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.50A 4d31A-2vdaA:
undetectable
4d31B-2vdaA:
undetectable		 4d31A-2vdaA:
20.58
4d31B-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 4d3bA-2vdaA:
1.4
4d3bB-2vdaA:
undetectable		 4d3bA-2vdaA:
20.58
4d3bB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 ASP A 139
ASN A 132
ASP A 209
GLU A 210
 None
 1.06A 4feuB-2vdaA:
undetectable		 4feuB-2vdaA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.43A 4fvxA-2vdaA:
undetectable
4fvxB-2vdaA:
undetectable		 4fvxA-2vdaA:
20.58
4fvxB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4fvzA-2vdaA:
undetectable
4fvzB-2vdaA:
undetectable		 4fvzA-2vdaA:
20.58
4fvzB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 ASP A 139
ASN A 132
ASP A 209
GLU A 210
 None
 1.24A 4gkhJ-2vdaA:
undetectable		 4gkhJ-2vdaA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4gqeA-2vdaA:
undetectable
4gqeB-2vdaA:
undetectable		 4gqeA-2vdaA:
20.58
4gqeB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 4jsiA-2vdaA:
undetectable
4jsiB-2vdaA:
undetectable		 4jsiA-2vdaA:
20.58
4jsiB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 5 GLU A 806
SER A 807
ARG A 792
PRO A 301
 None
 1.00A 4k17B-2vdaA:
2.7		 4k17B-2vdaA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 201
LYS A 202
LYS A 124
 None
 1.40A 4k50A-2vdaA:
undetectable		 4k50A-2vdaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 201
LYS A 202
LYS A 124
 None
 1.37A 4k50E-2vdaA:
undetectable		 4k50E-2vdaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 ARG A 201
LYS A 202
LYS A 124
 None
 1.38A 4k50I-2vdaA:
undetectable		 4k50I-2vdaA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.44A 4k5fA-2vdaA:
undetectable
4k5fB-2vdaA:
undetectable		 4k5fA-2vdaA:
20.58
4k5fB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.44A 4kciA-2vdaA:
undetectable
4kciB-2vdaA:
undetectable		 4kciA-2vdaA:
20.58
4kciB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.44A 4kckA-2vdaA:
undetectable
4kckB-2vdaA:
1.5		 4kckA-2vdaA:
20.58
4kckB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 4kclA-2vdaA:
undetectable
4kclB-2vdaA:
1.6		 4kclA-2vdaA:
20.58
4kclB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.49A 4upmA-2vdaA:
undetectable
4upmB-2vdaA:
undetectable		 4upmA-2vdaA:
20.58
4upmB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 4upnA-2vdaA:
undetectable
4upnB-2vdaA:
1.5		 4upnA-2vdaA:
20.58
4upnB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 GLU A 218
ALA A 219
PHE A 377
 None
 0.52A 4v1fA-2vdaA:
3.0		 4v1fA-2vdaA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 GLU A 218
ALA A 219
PHE A 377
 None
 0.48A 4v1fC-2vdaA:
3.5		 4v1fC-2vdaA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.46A 4v3uA-2vdaA:
undetectable
4v3uB-2vdaA:
undetectable		 4v3uA-2vdaA:
18.72
4v3uB-2vdaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.46A 4v3uC-2vdaA:
3.3
4v3uD-2vdaA:
undetectable		 4v3uC-2vdaA:
18.72
4v3uD-2vdaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.44A 4v3vA-2vdaA:
undetectable
4v3vB-2vdaA:
undetectable		 4v3vA-2vdaA:
20.58
4v3vB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 4v3yA-2vdaA:
undetectable
4v3yB-2vdaA:
undetectable		 4v3yA-2vdaA:
20.58
4v3yB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 5adcA-2vdaA:
undetectable
5adcB-2vdaA:
undetectable		 5adcA-2vdaA:
20.58
5adcB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 5agkA-2vdaA:
undetectable
5agkB-2vdaA:
1.6		 5agkA-2vdaA:
20.58
5agkB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 5aglA-2vdaA:
undetectable
5aglB-2vdaA:
undetectable		 5aglA-2vdaA:
20.58
5aglB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 5agoA-2vdaA:
undetectable
5agoB-2vdaA:
undetectable		 5agoA-2vdaA:
20.58
5agoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 5agoA-2vdaA:
undetectable
5agoB-2vdaA:
undetectable		 5agoA-2vdaA:
20.58
5agoB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 LEU A 387
VAL A 211
VAL A 129
PHE A 401
LEU A 407
 None
 1.39A 5cymA-2vdaA:
undetectable		 5cymA-2vdaA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 LEU A 387
VAL A 211
VAL A 129
PHE A 401
LEU A 407
 None
 1.40A 5cyqA-2vdaA:
undetectable		 5cyqA-2vdaA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 PHE A  68
ILE A  64
GLY A  91
LEU A 207
 None
 1.00A 5esmA-2vdaA:
undetectable		 5esmA-2vdaA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.62A 5qglA-2vdaA:
undetectable		 5qglA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.69A 5qguA-2vdaA:
undetectable		 5qguA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.69A 5qgvA-2vdaA:
undetectable		 5qgvA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.71A 5qgwA-2vdaA:
undetectable		 5qgwA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.70A 5qgxA-2vdaA:
undetectable		 5qgxA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.68A 5qh1A-2vdaA:
undetectable		 5qh1A-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.67A 5qh4A-2vdaA:
undetectable		 5qh4A-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.64A 5qhcA-2vdaA:
undetectable		 5qhcA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.68A 5qheA-2vdaA:
undetectable		 5qheA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		3 / 3 VAL A 328
VAL A 333
GLN A 366
 None
 0.66A 5qhgA-2vdaA:
undetectable		 5qhgA-2vdaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 HIS A 778
LEU A 785
PRO A 301
SER A 809
 None
 1.29A 5syjA-2vdaA:
2.1		 5syjA-2vdaA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 HIS A 778
LEU A 785
PRO A 301
SER A 809
 None
 1.28A 5syjB-2vdaA:
undetectable		 5syjB-2vdaA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 5vukA-2vdaA:
undetectable
5vukB-2vdaA:
undetectable		 5vukA-2vdaA:
20.58
5vukB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 5vulA-2vdaA:
undetectable
5vulB-2vdaA:
undetectable		 5vulA-2vdaA:
20.58
5vulB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 5vuqA-2vdaA:
undetectable
5vuqB-2vdaA:
undetectable		 5vuqA-2vdaA:
20.58
5vuqB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 5vuqA-2vdaA:
undetectable
5vuqB-2vdaA:
undetectable		 5vuqA-2vdaA:
20.58
5vuqB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 5vusA-2vdaA:
1.5
5vusB-2vdaA:
undetectable		 5vusA-2vdaA:
20.58
5vusB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 5vutA-2vdaA:
undetectable
5vutB-2vdaA:
undetectable		 5vutA-2vdaA:
20.58
5vutB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 5vuuA-2vdaA:
undetectable
5vuuB-2vdaA:
undetectable		 5vuuA-2vdaA:
20.58
5vuuB-2vdaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.49A 5vuvA-2vdaA:
1.6
5vuvB-2vdaA:
undetectable		 5vuvA-2vdaA:
19.44
5vuvB-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.47A 5vuwA-2vdaA:
undetectable
5vuwB-2vdaA:
undetectable		 5vuwA-2vdaA:
19.44
5vuwB-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.50A 5vuwA-2vdaA:
undetectable
5vuwB-2vdaA:
undetectable		 5vuwA-2vdaA:
19.44
5vuwB-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.45A 5vuyA-2vdaA:
1.6
5vuyB-2vdaA:
undetectable		 5vuyA-2vdaA:
19.44
5vuyB-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.40A 5vuyA-2vdaA:
1.6
5vuyB-2vdaA:
undetectable		 5vuyA-2vdaA:
19.44
5vuyB-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 5vv2A-2vdaA:
undetectable
5vv2B-2vdaA:
1.5		 5vv2A-2vdaA:
19.44
5vv2B-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.47A 5vv2A-2vdaA:
undetectable
5vv2B-2vdaA:
1.5		 5vv2A-2vdaA:
19.44
5vv2B-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.50A 5vv3A-2vdaA:
1.6
5vv3B-2vdaA:
undetectable		 5vv3A-2vdaA:
19.44
5vv3B-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.47A 5vv5A-2vdaA:
undetectable
5vv5B-2vdaA:
1.5		 5vv5A-2vdaA:
19.44
5vv5B-2vdaA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 GLU A  34
MET A  31
ARG A  53
VAL A  70
 None
 1.48A 6auwA-2vdaA:
undetectable
6auwB-2vdaA:
undetectable		 6auwA-2vdaA:
6.70
6auwB-2vdaA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.48A 6auyA-2vdaA:
undetectable
6auyB-2vdaA:
1.5		 6auyA-2vdaA:
6.70
6auyB-2vdaA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.50A 6av2A-2vdaA:
undetectable
6av2B-2vdaA:
undetectable		 6av2A-2vdaA:
6.70
6av2B-2vdaA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 7 MET A  31
ARG A  53
VAL A  70
GLU A  34
 None
 1.47A 6av4A-2vdaA:
undetectable
6av4B-2vdaA:
undetectable		 6av4A-2vdaA:
6.70
6av4B-2vdaA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 LEU A  54
LEU A  63
ALA A  67
GLY A 151
LEU A 152
 None
 0.93A 6b0iB-2vdaA:
2.0		 6b0iB-2vdaA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 6 ASP A 293
VAL A 287
GLU A 294
ALA A 690
 None
 1.23A 6djzB-2vdaA:
undetectable		 6djzB-2vdaA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		5 / 12 LEU A 387
VAL A 211
VAL A 129
PHE A 401
LEU A 407
 None
 1.39A 6eliA-2vdaA:
2.2		 6eliA-2vdaA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 8 TYR A 496
GLY A 553
SER A 583
VAL A 452
 None
 0.87A 6giqL-2vdaA:
undetectable
6giqP-2vdaA:
undetectable
6giqT-2vdaA:
undetectable		 6giqL-2vdaA:
20.79
6giqP-2vdaA:
12.97
6giqT-2vdaA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2vda TRANSLOCASE SUBUNIT
SECA
(Escherichia
coli) 		4 / 8 ASP A 568
HIS A 555
ARG A 572
ASP A 422
 None
 1.21A 6mn4C-2vdaA:
undetectable		 6mn4C-2vdaA:
16.92