SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		5 / 12 TYR A  93
THR A  94
GLY A  95
GLY A  49
THR A  97
 None
 1.22A 2azxA-2vdfA:
undetectable		 2azxA-2vdfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		5 / 12 TYR A  93
THR A  94
GLY A  95
GLY A  49
THR A  97
 None
 1.17A 2azxB-2vdfA:
undetectable		 2azxB-2vdfA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 ARG A 243
SER A 241
TYR A 213
 None
 1.06A 2q2hA-2vdfA:
undetectable
2q2hB-2vdfA:
undetectable		 2q2hA-2vdfA:
20.16
2q2hB-2vdfA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		4 / 8 TYR A  96
ASP A 144
GLU A 208
GLU A   9
 None
 1.27A 3dh0A-2vdfA:
undetectable		 3dh0A-2vdfA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		4 / 5 TYR A  96
ASP A 144
GLU A 208
GLU A   9
 None
 1.35A 3dh0B-2vdfA:
0.0		 3dh0B-2vdfA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 THR A 186
SER A 167
ARG A 134
 None
 0.72A 3phnA-2vdfA:
undetectable		 3phnA-2vdfA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 GLN A 215
PHE A 191
TYR A 213
 None
 0.88A 3ucjB-2vdfA:
undetectable		 3ucjB-2vdfA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 GLN A 215
PHE A 191
TYR A 213
 None
 0.90A 3ucjA-2vdfA:
undetectable		 3ucjA-2vdfA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1491_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 2vdf OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		4 / 4 GLY A 250
TRP A 158
GLU A 208
THR A  11
 None
 1.21A 4at0A-2vdfA:
0.0		 4at0A-2vdfA:
18.46