SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 8 GLU B 426
SER B 418
ILE B  23
LEU B 420
 None
 0.75A 1jg4A-2vduB:
undetectable		 1jg4A-2vduB:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 ARG B  14
ASP B 177
ASN B 179
GLU B 114
 None
 1.27A 1rjdA-2vduB:
undetectable		 1rjdA-2vduB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 ARG B  14
ASP B 177
ASN B 179
GLU B 114
 None
 1.29A 1rjdB-2vduB:
undetectable		 1rjdB-2vduB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 ARG B  14
ASP B 177
ASN B 179
GLU B 114
 None
 1.29A 1rjdC-2vduB:
undetectable		 1rjdC-2vduB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		3 / 3 ILE B 165
ASP B 168
PHE B 148
 None
 0.64A 1uwjB-2vduB:
undetectable		 1uwjB-2vduB:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 108
ILE B  22
ILE B  23
SER B 413
LEU B 117
 None
 1.02A 1xdkF-2vduB:
undetectable		 1xdkF-2vduB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 9 ALA B 266
SER B 257
LEU B 256
LEU B 345
HIS B 240
 None
 1.14A 1y7iA-2vduB:
undetectable		 1y7iA-2vduB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 10 ALA B 266
SER B 257
LEU B 256
LEU B 345
HIS B 240
 None
 1.15A 1y7iB-2vduB:
undetectable		 1y7iB-2vduB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		3 / 3 TRP B 269
LEU B 254
LYS B 342
 None
 1.33A 1yajK-2vduB:
undetectable		 1yajK-2vduB:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		3 / 3 SER B 316
THR B  12
GLN B 368
 None
 0.83A 2fk8A-2vduB:
undetectable		 2fk8A-2vduB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		3 / 3 CYH B 230
HIS B 226
PHE B 231
 None
 1.00A 3cr4X-2vduB:
undetectable		 3cr4X-2vduB:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 VAL B 414
GLY B  42
SER B  29
PHE B  30
ALA B  21
 None
 0.99A 3keeB-2vduB:
undetectable		 3keeB-2vduB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 VAL B 414
GLY B  42
SER B  29
PHE B  30
ALA B  21
 None
 1.03A 3keeC-2vduB:
undetectable		 3keeC-2vduB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 ILE B  22
ALA B  21
ALA B 384
THR B 370
 None
 0.99A 3mdrB-2vduB:
undetectable		 3mdrB-2vduB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		3 / 3 HIS B  37
SER B 408
GLU B 405
 None
 0.88A 3s8pA-2vduB:
undetectable		 3s8pA-2vduB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 288
ASP B 262
GLU B 307
VAL B 433
 None
 1.30A 4nkvA-2vduB:
undetectable		 4nkvA-2vduB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 5 ILE B 306
LEU B 288
ASP B 262
GLU B 307
VAL B 433
 None
 1.30A 4nkxB-2vduB:
undetectable		 4nkxB-2vduB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 ASP B 234
HIS B 226
ILE B 204
TYR B 253
 None
 1.23A 5ih0A-2vduB:
1.4		 5ih0A-2vduB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 313
VAL B 310
GLY B 259
ASP B 261
HIS B 240
 None
 1.21A 5nnaA-2vduB:
undetectable		 5nnaA-2vduB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 313
VAL B 310
GLY B 259
ASP B 261
HIS B 240
 None
 1.19A 5nnaD-2vduB:
undetectable		 5nnaD-2vduB:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		4 / 6 PHE B 265
TRP B 267
SER B 276
GLY B 343
 None
 1.13A 5o4yF-2vduB:
undetectable		 5o4yF-2vduB:
4.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 2vdu TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE-ASSOCI
ATED WD REPEAT
PROTEIN TRM82
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 264
VAL B 326
LEU B 335
SER B 246
LEU B 283
 None
 0.85A 6b52A-2vduB:
undetectable		 6b52A-2vduB:
20.98