SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2veo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		3 / 3 THR A  23
PRO A  25
THR A  24
 None
 0.88A 1a7yB-2veoA:
undetectable		 1a7yB-2veoA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 6 HIS A 366
ALA A 187
GLY A 182
TYR A 183
 None
 1.14A 1c8lA-2veoA:
undetectable		 1c8lA-2veoA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.12A 1dhfA-2veoA:
undetectable		 1dhfA-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.11A 1dlsA-2veoA:
undetectable		 1dlsA-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 GLY A 240
SER A 239
LEU A 264
ILE A 252
ILE A 304
 None
 1.25A 1kyvA-2veoA:
3.5
1kyvE-2veoA:
undetectable		 1kyvA-2veoA:
15.29
1kyvE-2veoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 304
GLY A 240
SER A 239
LEU A 264
ILE A 252
 None
 1.25A 1kyvB-2veoA:
3.5
1kyvC-2veoA:
2.9		 1kyvB-2veoA:
15.29
1kyvC-2veoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 304
GLY A 240
SER A 239
LEU A 264
ILE A 252
 None
 1.24A 1kyvC-2veoA:
2.9
1kyvD-2veoA:
3.3		 1kyvC-2veoA:
15.29
1kyvD-2veoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 304
GLY A 240
SER A 239
LEU A 264
ILE A 252
 None
 1.25A 1kyvD-2veoA:
3.3
1kyvE-2veoA:
undetectable		 1kyvD-2veoA:
15.29
1kyvE-2veoA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 TYR A 107
THR A 123
GLY A 186
THR A 190
 None
 0.96A 2a1mA-2veoA:
undetectable		 2a1mA-2veoA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 LEU A 166
ASN A 168
GLY A 162
GLY A  34
LEU A 172
 None
 0.94A 2egvA-2veoA:
undetectable		 2egvA-2veoA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 LEU A 166
ASN A 168
GLY A 162
GLY A  34
LEU A 172
 None
 0.98A 2egvB-2veoA:
undetectable		 2egvB-2veoA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 11 TYR A 183
GLY A 185
ASP A  95
ILE A 336
THR A 221
 None
PG4  A1443 ( 4.3A)
PG4  A1443 (-3.1A)
None
PG4  A1443 (-4.1A)
 1.14A 2f9wA-2veoA:
undetectable
2f9wB-2veoA:
undetectable		 2f9wA-2veoA:
21.68
2f9wB-2veoA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 9 THR A 123
TYR A 105
THR A 118
ALA A 119
LEU A 108
 None
 1.17A 2npnA-2veoA:
2.1		 2npnA-2veoA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.11A 2w3bA-2veoA:
undetectable		 2w3bA-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.08A 2w3bB-2veoA:
undetectable		 2w3bB-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.05A 2w3mA-2veoA:
undetectable		 2w3mA-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 SER A 377
PHE A  88
ILE A 381
TRP A 129
 None
 0.76A 2y7kA-2veoA:
undetectable		 2y7kA-2veoA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 PHE A 327
PHE A 435
GLY A 432
ALA A 430
THR A 118
 None
 1.37A 3ld6B-2veoA:
undetectable		 3ld6B-2veoA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 LEU A 160
VAL A  92
GLY A 182
ILE A 163
ILE A 159
 None
 0.89A 3s54A-2veoA:
undetectable		 3s54A-2veoA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 5 PHE A 431
GLY A 186
ILE A 336
VAL A 337
 None
 0.79A 3wrkA-2veoA:
undetectable		 3wrkA-2veoA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 PHE A  88
ILE A 126
ILE A 381
ALA A 187
GLY A 185
 None
None
None
None
PG4  A1443 ( 4.3A)
 1.15A 4enhA-2veoA:
undetectable		 4enhA-2veoA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 8 GLU A 253
ASN A 257
GLN A 261
GLY A 260
 None
 0.87A 4f93B-2veoA:
undetectable		 4f93B-2veoA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		3 / 3 GLN A  58
THR A  24
THR A  23
 None
 0.82A 4fu9A-2veoA:
undetectable		 4fu9A-2veoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		3 / 3 GLN A  58
THR A  24
THR A  23
 None
 0.82A 4fufA-2veoA:
undetectable		 4fufA-2veoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 ILE A 381
ALA A 179
VAL A 178
TYR A 135
 None
 0.79A 4g77A-2veoA:
undetectable		 4g77A-2veoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFJ_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ILE A 150
ALA A 148
ILE A 301
PRO A 300
LEU A 305
 PG4  A1443 ( 4.1A)
None
None
None
None
 1.07A 4kfjB-2veoA:
undetectable		 4kfjB-2veoA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 8 PHE A 380
SER A 210
GLY A 208
ALA A 354
 None
 0.91A 4m48A-2veoA:
undetectable		 4m48A-2veoA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		3 / 3 LYS A 382
ASN A 357
ASP A 386
 None
 0.85A 4o1eA-2veoA:
undetectable		 4o1eA-2veoA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 9 LEU A  57
GLN A  56
VAL A  42
THR A  44
ILE A  46
 None
 1.48A 4pcuA-2veoA:
1.0
4pcuB-2veoA:
1.3		 4pcuA-2veoA:
22.81
4pcuB-2veoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 8 ALA A 218
GLY A 237
LEU A 241
GLU A 155
 PG4  A1443 (-4.4A)
PG4  A1443 (-3.6A)
PG4  A1443 ( 4.9A)
None
 0.83A 4po0A-2veoA:
undetectable		 4po0A-2veoA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 PHE A 233
LEU A 367
GLU A 181
ASP A 122
GLY A 213
 PG4  A1443 (-4.7A)
None
None
None
None
 1.35A 4qb9E-2veoA:
1.1		 4qb9E-2veoA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 MET A 157
GLU A 154
GLU A 155
GLU A 308
 None
 1.19A 4r87I-2veoA:
0.6		 4r87I-2veoA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 5 THR A 190
ALA A 187
TYR A  90
HIS A 211
 None
 1.25A 5ecmA-2veoA:
undetectable		 5ecmA-2veoA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 9 THR A 214
GLY A 182
ALA A 209
HIS A 188
THR A 190
 None
 1.45A 5eeuA-2veoA:
undetectable
5eeuB-2veoA:
undetectable		 5eeuA-2veoA:
9.68
5eeuB-2veoA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 ILE A 404
GLY A 403
PHE A 358
PHE A 380
 None
 1.03A 5hieA-2veoA:
undetectable		 5hieA-2veoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 PHE A 431
GLY A 186
ILE A 336
VAL A 337
 None
 0.64A 5ik1A-2veoA:
undetectable		 5ik1A-2veoA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		5 / 12 ASP A  18
ALA A  11
THR A 118
ARG A 270
GLY A 271
 None
 1.20A 5m5cB-2veoA:
2.4		 5m5cB-2veoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 2veo LIPASE A
(Moesziomyces
antarcticus) 		4 / 7 TYR A  22
PHE A 145
ALA A 158
GLY A 162
 None
 0.96A 5uxdA-2veoA:
undetectable		 5uxdA-2veoA:
23.30