SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 7 ARG A 473
ASP A 295
THR A 402
GLY A 401
 None
 1.03A 2f6dA-2vf1A:
undetectable		 2f6dA-2vf1A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		3 / 3 ILE A 366
ILE A 472
LEU A 556
 None
 0.54A 2prgA-2vf1A:
undetectable		 2prgA-2vf1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 6 ALA A 178
ILE A 236
LEU A 313
ALA A 319
 None
 0.91A 3r9sA-2vf1A:
undetectable		 3r9sA-2vf1A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 7 TRP A 380
ASN A 375
LEU A 518
PHE A 449
 None
 1.39A 4awuA-2vf1A:
undetectable		 4awuA-2vf1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		5 / 12 PHE A 245
ALA A 145
TYR A 152
LEU A 584
LEU A 342
 None
 1.13A 4qzuB-2vf1A:
0.0		 4qzuB-2vf1A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		5 / 12 PHE A 245
ALA A 145
TYR A 152
LEU A 584
LEU A 342
 None
 1.20A 4qzuC-2vf1A:
undetectable		 4qzuC-2vf1A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 7 SER A 274
ARG A 125
ALA A 212
LEU A 211
 None
 1.08A 4xk8A-2vf1A:
undetectable		 4xk8A-2vf1A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		3 / 3 ARG A 308
VAL A 298
TRP A 296
 None
 1.25A 5fvoA-2vf1A:
undetectable		 5fvoA-2vf1A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		3 / 3 ALA A 227
ASN A 230
LEU A 231
 None
 0.46A 5i1nC-2vf1A:
undetectable		 5i1nC-2vf1A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		3 / 3 ALA A 227
ASN A 230
LEU A 231
 None
 0.49A 5i1pD-2vf1A:
undetectable		 5i1pD-2vf1A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 9 ILE A 416
VAL A 505
THR A 537
ASN A 548
 None
 0.82A 5lg3I-2vf1A:
undetectable		 5lg3I-2vf1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		5 / 9 ILE A 236
ALA A 178
ILE A 175
ILE A 248
LEU A 241
 None
 1.04A 5mvmA-2vf1A:
undetectable
5mvmE-2vf1A:
undetectable		 5mvmA-2vf1A:
11.07
5mvmE-2vf1A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		5 / 9 SER A 520
GLY A 377
ALA A 515
SER A 514
GLY A 517
 None
 1.16A 6bklE-2vf1A:
undetectable
6bklF-2vf1A:
undetectable
6bklG-2vf1A:
undetectable
6bklH-2vf1A:
undetectable		 6bklE-2vf1A:
5.28
6bklF-2vf1A:
5.28
6bklG-2vf1A:
5.28
6bklH-2vf1A:
5.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		5 / 10 GLY A 468
ASN A 571
ILE A 472
ALA A 445
THR A 370
 None
 1.12A 6e5zA-2vf1A:
undetectable		 6e5zA-2vf1A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 2vf1 CAPSID PROTEIN
(Rabbit
picobirnavirus) 		4 / 5 PHE A 272
VAL A 298
PRO A 130
VAL A 254
 None
 0.96A 6ekzA-2vf1A:
undetectable		 6ekzA-2vf1A:
10.71