SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 GLY A 366
GLU A 372
SER A 369
TYR A 315
 TRS  A1478 ( 3.5A)
UDP  A1477 (-2.6A)
UDP  A1477 (-2.6A)
EDO  A1480 (-4.8A)
 0.96A 1maaD-2vg8A:
undetectable		 1maaD-2vg8A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 LEU A 371
SER A 373
LEU A 353
THR A 140
HIS A 364
 None
None
None
TRS  A1478 ( 4.4A)
UDP  A1477 (-3.9A)
 1.35A 1mmtA-2vg8A:
undetectable		 1mmtA-2vg8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 162
LEU A 154
LEU A 197
LEU A 183
MET A 391
 None
 1.40A 1p33C-2vg8A:
5.4		 1p33C-2vg8A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 295
PHE A 300
ASN A 287
 None
 0.72A 1sg9B-2vg8A:
2.0		 1sg9B-2vg8A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 SER A 373
PHE A 361
GLN A 349
GLU A 372
 None
None
UDP  A1477 (-3.3A)
UDP  A1477 (-2.6A)
 1.28A 2c8aA-2vg8A:
undetectable		 2c8aA-2vg8A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  42
ALA A  43
ALA A 123
LEU A  97
SER A  93
 EDO  A1483 (-4.8A)
None
None
None
None
 1.12A 2h77A-2vg8A:
undetectable		 2h77A-2vg8A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 353
GLN A 349
VAL A 273
MET A 427
LEU A 271
 None
UDP  A1477 (-3.3A)
None
None
None
 1.33A 2q7kA-2vg8A:
undetectable		 2q7kA-2vg8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 118
GLY A 120
VAL A 144
SER A  87
PRO A 139
 None
None
None
None
TRS  A1478 (-4.1A)
 1.35A 2vmyB-2vg8A:
3.1		 2vmyB-2vg8A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  24
SER A 277
ILE A  42
ILE A  86
TYR A 386
 None
UDP  A1477 (-2.5A)
EDO  A1483 (-4.8A)
EDO  A1480 (-4.9A)
None
 1.26A 3g8iA-2vg8A:
undetectable		 3g8iA-2vg8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 THR A 141
LEU A 396
ILE A 400
HIS A 364
TYR A 386
 None
None
None
UDP  A1477 (-3.9A)
None
 1.37A 3gwxB-2vg8A:
undetectable		 3gwxB-2vg8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 ILE A 378
SER A 269
SER A 357
GLY A 359
LEU A 353
 None
 1.21A 3iluB-2vg8A:
undetectable
3iluE-2vg8A:
undetectable		 3iluB-2vg8A:
19.58
3iluE-2vg8A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 SER A 274
ILE A 343
CYH A 258
PHE A 361
SER A 369
 UDP  A1477 ( 3.7A)
None
None
None
UDP  A1477 (-2.6A)
 1.45A 3ko0G-2vg8A:
0.0
3ko0H-2vg8A:
undetectable
3ko0I-2vg8A:
0.0
3ko0J-2vg8A:
0.0		 3ko0G-2vg8A:
12.24
3ko0H-2vg8A:
12.24
3ko0I-2vg8A:
12.24
3ko0J-2vg8A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 SER A 274
ILE A 343
CYH A 258
SER A 369
PHE A 361
 UDP  A1477 ( 3.7A)
None
None
UDP  A1477 (-2.6A)
None
 1.40A 3ko0Q-2vg8A:
undetectable
3ko0R-2vg8A:
0.0
3ko0S-2vg8A:
0.0
3ko0T-2vg8A:
undetectable		 3ko0Q-2vg8A:
12.24
3ko0R-2vg8A:
12.24
3ko0S-2vg8A:
12.24
3ko0T-2vg8A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 HIS A  19
SER A  14
GLU A  45
ASP A  75
 EDO  A1480 ( 3.8A)
None
None
None
 1.13A 4blvA-2vg8A:
2.5		 4blvA-2vg8A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 GLU A 219
TRP A 367
LYS A 224
 None
 1.40A 4k7aA-2vg8A:
undetectable		 4k7aA-2vg8A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 ILE A 310
SER A 313
ASP A 184
ASP A 181
 None
 1.50A 4krhB-2vg8A:
undetectable		 4krhB-2vg8A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 VAL A 414
LEU A 413
LEU A 281
PHE A 300
 None
None
EDO  A1481 (-4.0A)
None
 1.11A 4o1zA-2vg8A:
undetectable		 4o1zA-2vg8A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 7 LEU A 395
THR A 370
THR A 214
LEU A 218
THR A 141
 None
 1.49A 4z91F-2vg8A:
undetectable
4z91G-2vg8A:
undetectable
4z91H-2vg8A:
undetectable
4z91I-2vg8A:
undetectable
4z91J-2vg8A:
undetectable		 4z91F-2vg8A:
20.65
4z91G-2vg8A:
20.65
4z91H-2vg8A:
20.65
4z91I-2vg8A:
20.65
4z91J-2vg8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 THR A 141
GLY A 366
ALA A 393
THR A 370
 None
TRS  A1478 ( 3.5A)
None
None
 0.98A 5eevL-2vg8A:
undetectable
5eevV-2vg8A:
undetectable		 5eevL-2vg8A:
9.51
5eevV-2vg8A:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 THR A 141
GLY A 366
ALA A 393
THR A 370
 None
TRS  A1478 ( 3.5A)
None
None
 0.98A 5eewL-2vg8A:
undetectable
5eewV-2vg8A:
undetectable		 5eewL-2vg8A:
9.51
5eewV-2vg8A:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 THR A 141
GLY A 366
ALA A 393
THR A 370
 None
TRS  A1478 ( 3.5A)
None
None
 0.98A 5ef3L-2vg8A:
undetectable
5ef3V-2vg8A:
undetectable		 5ef3L-2vg8A:
9.51
5ef3V-2vg8A:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 TYR A 315
ASP A 117
HIS A  19
ILE A  21
 EDO  A1480 (-4.8A)
None
EDO  A1480 ( 3.8A)
UDP  A1477 (-3.7A)
 1.20A 5ih0A-2vg8A:
undetectable		 5ih0A-2vg8A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 ILE A  11
LEU A 242
HIS A  32
VAL A  31
 None
 1.20A 5jmnB-2vg8A:
undetectable		 5jmnB-2vg8A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 396
ALA A 382
ARG A 421
GLY A 425
LEU A 426
 None
 1.01A 5m5cB-2vg8A:
4.2		 5m5cB-2vg8A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		6 / 12 LEU A  23
ASP A 117
ALA A 207
PHE A 124
LEU A  97
VAL A  90
 None
 1.25A 5tudA-2vg8A:
undetectable		 5tudA-2vg8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ASP A 117
ALA A 207
PHE A 124
LEU A  97
VAL A  90
 None
 1.06A 5tudD-2vg8A:
undetectable		 5tudD-2vg8A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 LEU A  23
ALA A  27
LEU A  30
LEU A  59
 None
 0.75A 5vkqA-2vg8A:
undetectable
5vkqD-2vg8A:
undetectable		 5vkqA-2vg8A:
14.01
5vkqD-2vg8A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 LEU A  59
LEU A  23
ALA A  27
LEU A  30
 None
 0.77A 5vkqA-2vg8A:
undetectable
5vkqB-2vg8A:
undetectable		 5vkqA-2vg8A:
14.01
5vkqB-2vg8A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 LEU A  59
LEU A  23
ALA A  27
LEU A  30
 None
 0.81A 5vkqB-2vg8A:
undetectable
5vkqC-2vg8A:
undetectable		 5vkqB-2vg8A:
14.01
5vkqC-2vg8A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 LEU A  59
LEU A  23
ALA A  27
LEU A  30
 None
 0.78A 5vkqC-2vg8A:
undetectable
5vkqD-2vg8A:
undetectable		 5vkqC-2vg8A:
14.01
5vkqD-2vg8A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.88A 5xioA-2vg8A:
3.4		 5xioA-2vg8A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.85A 5xiqB-2vg8A:
2.7		 5xiqB-2vg8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 2vg8 HYDROQUINONE
GLUCOSYLTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 140
GLU A 388
HIS A 364
 TRS  A1478 ( 4.4A)
TRS  A1478 (-2.8A)
UDP  A1477 (-3.9A)
 0.87A 5xiqD-2vg8A:
2.2		 5xiqD-2vg8A:
22.48