SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vga'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2vga PROTEIN A41
(Vaccinia
virus) 		4 / 6 LEU A 128
PHE A 133
LEU A 192
PHE A 196
 None
 1.08A 3wg7C-2vgaA:
undetectable
3wg7J-2vgaA:
undetectable		 3wg7C-2vgaA:
19.71
3wg7J-2vgaA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 2vga PROTEIN A41
(Vaccinia
virus) 		4 / 7 SER A  80
GLU A  17
ASP A 164
THR A 176
 None
 1.04A 4uacA-2vgaA:
undetectable		 4uacA-2vgaA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2vga PROTEIN A41
(Vaccinia
virus) 		4 / 7 VAL A  18
ILE A  16
VAL A 106
ILE A 108
 None
 0.76A 5bmvC-2vgaA:
undetectable		 5bmvC-2vgaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2vga PROTEIN A41
(Vaccinia
virus) 		5 / 12 VAL A  44
ILE A  16
VAL A 160
VAL A  65
PHE A  62
 None
 1.21A 6ap6A-2vgaA:
undetectable		 6ap6A-2vgaA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 2vga PROTEIN A41
(Vaccinia
virus) 		5 / 12 VAL A  44
ILE A  16
VAL A 160
VAL A  65
PHE A  62
 None
 1.22A 6ap6B-2vgaA:
undetectable		 6ap6B-2vgaA:
18.66