SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2vh1 CELL DIVISION
PROTEIN FTSQ
(Escherichia
coli) 		4 / 7 ALA A 167
PHE A 145
ARG A 131
ASN A 133
 None
 1.21A 1t9wA-2vh1A:
undetectable		 1t9wA-2vh1A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 2vh1 CELL DIVISION
PROTEIN FTSQ
(Escherichia
coli) 		4 / 5 LEU A 181
LEU A 188
LEU A 171
MET A 193
 None
 0.90A 2oaxF-2vh1A:
undetectable		 2oaxF-2vh1A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2vh1 CELL DIVISION
PROTEIN FTSQ
(Escherichia
coli) 		4 / 7 ILE A  99
LEU A 103
THR A  63
LEU A  62
 None
 1.00A 5xdqA-2vh1A:
undetectable
5xdqJ-2vh1A:
undetectable		 5xdqA-2vh1A:
17.64
5xdqJ-2vh1A:
13.64