SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vhd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 8 GLN A 185
LEU A 206
LEU A 174
SER A 168
 None
 0.99A 1hk2A-2vhdA:
undetectable		 1hk2A-2vhdA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 8 GLN A 185
LEU A 206
LEU A 174
SER A 168
 None
 1.12A 1hk3A-2vhdA:
undetectable		 1hk3A-2vhdA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 206
ASN A 205
GLY A 207
THR A 165
ILE A  14
 None
 1.27A 1p93A-2vhdA:
undetectable		 1p93A-2vhdA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  61
GLY A  60
LEU A 163
PRO A 304
ASN A  52
 None
 0.95A 1qzzA-2vhdA:
undetectable		 1qzzA-2vhdA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  61
GLY A  60
LEU A 163
PRO A 304
ASN A  52
 None
 0.97A 1xdsA-2vhdA:
undetectable		 1xdsA-2vhdA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  61
GLY A  60
LEU A 163
PRO A 304
ASN A  52
 None
 0.91A 1xdsB-2vhdA:
undetectable		 1xdsB-2vhdA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 7 HIS A  55
ALA A  62
GLY A  60
GLY A  61
 HEC  A 401 (-3.3A)
None
None
None
 0.75A 2c49B-2vhdA:
undetectable		 2c49B-2vhdA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 6 SER A 168
ARG A 251
LEU A 250
PHE A 170
 None
None
HEC  A 402 (-4.9A)
None
 1.24A 2f8dA-2vhdA:
undetectable		 2f8dA-2vhdA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 11 ILE A 109
GLU A 160
HIS A  55
GLY A 107
GLU A 114
 None
HEC  A 401 (-3.5A)
HEC  A 401 (-3.3A)
None
HEC  A 401 (-4.0A)
 1.48A 2fn1B-2vhdA:
undetectable		 2fn1B-2vhdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 299
LEU A 296
ALA A 294
LEU A 181
ASP A 182
 None
 1.19A 3gwuA-2vhdA:
undetectable		 3gwuA-2vhdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  89
LEU A 299
ARG A 251
ILE A  14
THR A 165
 HEC  A 401 ( 4.9A)
None
None
None
None
 1.31A 4o5fA-2vhdA:
undetectable
4o5fB-2vhdA:
undetectable		 4o5fA-2vhdA:
22.85
4o5fB-2vhdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  83
ALA A  86
ASN A  89
GLN A  92
 HEC  A 401 ( 4.8A)
HEC  A 401 ( 4.3A)
HEC  A 401 ( 4.9A)
HEC  A 401 (-4.5A)
 1.18A 4zgfA-2vhdA:
undetectable		 4zgfA-2vhdA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 208
THR A  67
PRO A  81
 None
None
HEC  A 401 (-4.5A)
 0.64A 5v5zA-2vhdA:
undetectable		 5v5zA-2vhdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  42
PHE A  38
LEU A 311
 None
 0.83A 5x1bC-2vhdA:
undetectable		 5x1bC-2vhdA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 181
GLN A 185
LEU A 296
LEU A 299
 None
 1.05A 5yvnA-2vhdA:
undetectable		 5yvnA-2vhdA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		4 / 7 THR A 125
LEU A 121
ILE A 109
THR A 118
 None
 0.85A 5zsfA-2vhdA:
undetectable
5zsfB-2vhdA:
undetectable		 5zsfA-2vhdA:
13.43
5zsfB-2vhdA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 210
PHE A 192
ALA A 254
THR A 256
MET A 275
 None
None
None
CA  A 403 (-4.7A)
HEC  A 402 (-2.3A)
 1.33A 6aycA-2vhdA:
undetectable		 6aycA-2vhdA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  34
ALA A 155
ILE A 109
LEU A  43
PRO A 119
 None
 1.16A 6b3aA-2vhdA:
undetectable		 6b3aA-2vhdA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2vhd CYTOCHROME C551
PEROXIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  34
ALA A 155
ILE A 109
LEU A  43
PRO A 119
 None
 1.18A 6b3bA-2vhdA:
undetectable		 6b3bA-2vhdA:
20.48