SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vhe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 LEU A 153
SER A 169
ASN A 150
 None
 0.82A 1bx4A-2vheA:
undetectable		 1bx4A-2vheA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A 172
SER A 157
ALA A 139
HIS A 134
ILE A 129
 COA  A 300 (-3.5A)
None
None
None
None
 0.97A 1gtnL-2vheA:
undetectable
1gtnV-2vheA:
undetectable		 1gtnL-2vheA:
15.62
1gtnV-2vheA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 HIS A 134
ILE A 129
GLY A 172
SER A 157
ALA A 139
 None
None
COA  A 300 (-3.5A)
None
None
 0.95A 1utdL-2vheA:
undetectable
1utdM-2vheA:
undetectable		 1utdL-2vheA:
15.62
1utdM-2vheA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 HIS A 134
ILE A 129
GLY A 172
SER A 157
ALA A 139
 None
None
COA  A 300 (-3.5A)
None
None
 0.95A 1utdO-2vheA:
undetectable
1utdP-2vheA:
undetectable		 1utdO-2vheA:
15.62
1utdP-2vheA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ILE A 105
LEU A 117
LYS A 149
GLY A 130
 None
 0.89A 4hb6A-2vheA:
undetectable		 4hb6A-2vheA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A 174
ALA A 175
LEU A 177
LEU A 160
LEU A 163
 None
 0.89A 4o1zA-2vheA:
undetectable		 4o1zA-2vheA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ALA A   2
ALA A  23
MET A  26
GLY A  27
GLU A   5
 None
 0.95A 4r29C-2vheA:
undetectable		 4r29C-2vheA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 2vhe ACETYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 ALA A   2
ALA A  23
MET A  26
GLY A  27
GLU A   5
 None
 1.01A 4r29D-2vheA:
undetectable		 4r29D-2vheA:
24.61