SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	4 / 5	TYR A 13 VAL A 62 SER A 72 GLY A 20	None	1.45A	3v4tA-2vi7A: undetectable 3v4tD-2vi7A: undetectable	3v4tA-2vi7A: 19.81 3v4tD-2vi7A: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_B_LNLB701_2 (PROSTAGLANDIN G/H SYNTHASE 2)	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	4 / 7	VAL A 162 TYR A 128 VAL A 127 VAL A 93	None	1.09A	4e1gB-2vi7A: undetectable	4e1gB-2vi7A: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_A_LYAA302_1 (THYMIDYLATE SYNTHASE)	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	5 / 12	HIS A 50 LEU A 21 GLY A 20 VAL A 62 ALA A 63	None	1.22A	4fqsA-2vi7A: undetectable	4fqsA-2vi7A: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_B_LYAB302_1 (THYMIDYLATE SYNTHASE)	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	5 / 12	HIS A 50 LEU A 21 GLY A 20 VAL A 62 ALA A 63	None	1.20A	4fqsB-2vi7A: undetectable	4fqsB-2vi7A: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CE2_B_SVRB202_1 ()	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	4 / 8	LEU A 21 LEU A 24 LEU A 61 ARG A 105	None	0.94A	6ce2A-2vi7A: undetectable	6ce2A-2vi7A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA810_0 (GEPHYRIN)	2vi7	ACETYLTRANSFERASE PA1377 (Pseudomonas aeruginosa)	3 / 3	LEU A 61 LEU A 59 ARG A 12	None	0.63A	6fgdA-2vi7A: 2.2	6fgdA-2vi7A: 19.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3V4T_A_ACTA502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",4,"TYR A  13;VAL A  62;SER A  72;GLY A  20","None","1.45A","3v4tA-2vi7A:undetectable;3v4tD-2vi7A:undetectable","3v4tA-2vi7A:19.81;3v4tD-2vi7A:19.81"],["4E1G_B_LNLB701_2","PROSTAGLANDIN G\/H SYNTHASE 2","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",4,"VAL A 162;TYR A 128;VAL A 127;VAL A  93","None","1.09A","4e1gB-2vi7A:undetectable","4e1gB-2vi7A:14.54"],["4FQS_A_LYAA302_1","THYMIDYLATE SYNTHASE","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",5,"HIS A  50;LEU A  21;GLY A  20;VAL A  62;ALA A  63","None","1.22A","4fqsA-2vi7A:undetectable","4fqsA-2vi7A:22.34"],["4FQS_B_LYAB302_1","THYMIDYLATE SYNTHASE","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",5,"HIS A  50;LEU A  21;GLY A  20;VAL A  62;ALA A  63","None","1.20A","4fqsB-2vi7A:undetectable","4fqsB-2vi7A:22.34"],["6CE2_B_SVRB202_1",";","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",4,"LEU A  21;LEU A  24;LEU A  61;ARG A 105","None","0.94A","6ce2A-2vi7A:undetectable","6ce2A-2vi7A:21.02"],["6FGD_A_ACTA810_0","GEPHYRIN","2vi7","ACETYLTRANSFERASE PA1377","Pseudomonas aeruginosa",3,"LEU A  61;LEU A  59;ARG A  12","None","0.63A","6fgdA-2vi7A:2.2","6fgdA-2vi7A:19.56"]]