SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		4 / 7 PHE A 173
ASN A  37
ASN A 156
VAL A 161
 None
 1.28A 1wu8A-2vidA:
undetectable
1wu8C-2vidA:
undetectable		 1wu8A-2vidA:
23.05
1wu8C-2vidA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 11 SER A 157
TYR A  44
ALA A  24
GLY A 155
SER A 154
 None
 1.22A 2xf3A-2vidA:
undetectable		 2xf3A-2vidA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 ILE A  34
VAL A  19
GLY A  17
LEU A 168
PRO A 160
 None
 1.18A 3em0B-2vidA:
undetectable		 3em0B-2vidA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		4 / 8 TYR A 106
PHE A 190
VAL A 188
ILE A 202
 None
 0.86A 3hjoA-2vidA:
undetectable		 3hjoA-2vidA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.75A 3keeA-2vidA:
13.3		 3keeA-2vidA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.73A 3keeB-2vidA:
13.4		 3keeB-2vidA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.76A 3keeC-2vidA:
12.9		 3keeC-2vidA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.76A 3keeD-2vidA:
13.2		 3keeD-2vidA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.77A 3sueA-2vidA:
12.1		 3sueA-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.72A 3sueB-2vidA:
12.2		 3sueB-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.77A 3sueC-2vidA:
11.8		 3sueC-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.71A 3sueD-2vidA:
12.3		 3sueD-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.74A 3sufA-2vidA:
12.3		 3sufA-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.74A 3sufB-2vidA:
12.1		 3sufB-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 11 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.82A 3sufC-2vidA:
5.7		 3sufC-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.93A 3sufD-2vidA:
6.5		 3sufD-2vidA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		4 / 8 VAL A 101
HIS A  53
VAL A  28
ILE A  34
 None
 0.88A 4jq1B-2vidA:
undetectable		 4jq1B-2vidA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		3 / 3 HIS A 123
VAL A  18
LEU A 131
 None
 0.75A 4m2vA-2vidA:
undetectable		 4m2vA-2vidA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		3 / 3 THR A 135
HIS A  53
LEU A 131
 None
 0.84A 5axdC-2vidA:
undetectable		 5axdC-2vidA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 ILE A 171
LEU A 168
PHE A  27
GLY A  26
GLY A 158
 None
 1.06A 5l6eA-2vidA:
undetectable		 5l6eA-2vidA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 10 GLY A 187
HIS A 172
VAL A 118
PRO A 160
GLY A 170
 None
 1.50A 5vncC-2vidA:
undetectable		 5vncC-2vidA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 VAL A 138
GLY A 170
GLY A 187
GLU A  76
TYR A 106
 None
 1.23A 5x7fA-2vidA:
undetectable		 5x7fA-2vidA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 2vid SERINE PROTEASE SPLB
(Staphylococcus
aureus) 		5 / 12 HIS A  39
ASP A  77
GLY A 155
SER A 157
ALA A 174
 None
 0.71A 6c2mC-2vidA:
12.1		 6c2mC-2vidA:
18.04