SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vii'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		5 / 12 LEU A 229
TYR A 220
ILE A 186
LEU A 247
THR A 210
 None
 1.01A 1p91B-2viiA:
undetectable		 1p91B-2viiA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		5 / 12 PHE A  60
LEU A 176
VAL A  18
GLN A  21
ALA A  26
 None
 1.48A 4a84A-2viiA:
undetectable		 4a84A-2viiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		5 / 12 LEU A  77
LEU A  73
ARG A  98
ILE A  61
THR A 111
 None
 1.30A 4f4dA-2viiA:
undetectable		 4f4dA-2viiA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		3 / 3 SER A  54
ARG A  55
HIS A  50
 None
 0.99A 4mjwA-2viiA:
undetectable
4mjwB-2viiA:
undetectable		 4mjwA-2viiA:
20.86
4mjwB-2viiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		5 / 10 VAL A 142
LEU A 106
ARG A  95
GLY A  94
PHE A  96
 None
 0.98A 5mxbA-2viiA:
undetectable		 5mxbA-2viiA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		4 / 6 ILE A 195
ILE A 186
LEU A 217
PHE A 209
 None
 0.99A 5vkqB-2viiA:
undetectable
5vkqC-2viiA:
undetectable		 5vkqB-2viiA:
9.52
5vkqC-2viiA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2vii PSP OPERON
TRANSCRIPTIONAL
ACTIVATOR
(Escherichia
coli) 		4 / 6 ILE A 195
ILE A 186
LEU A 217
PHE A 209
 None
 0.98A 5vkqC-2viiA:
undetectable
5vkqD-2viiA:
undetectable		 5vkqC-2viiA:
9.52
5vkqD-2viiA:
9.52