SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vjh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 11 ALA B 140
LEU B 105
ASP B 170
GLY B 166
ALA B 173
 PUB  B1050 ( 4.0A)
None
None
None
None
 1.10A 1b02A-2vjhB:
undetectable		 1b02A-2vjhB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 ASN B 144
ALA B  43
ASN B  47
 None
 0.72A 1n4fA-2vjhB:
undetectable		 1n4fA-2vjhB:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 SER B  46
ASP B  39
CYH B 158
 None
PEB  B1158 (-3.3A)
PEB  B1158 (-1.6A)
 1.07A 2br4E-2vjhB:
undetectable		 2br4E-2vjhB:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 LEU B 113
TYR B 117
GLY B 121
 PEB  B1082 (-4.5A)
None
MEN  B  72 ( 4.5A)
 0.60A 2ocuA-2vjhB:
undetectable		 2ocuA-2vjhB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
(Gloeobacter
violaceus) 		4 / 6 MET A 144
GLY A 145
GLU A 151
ARG A  33
 None
 1.40A 4bqfA-2vjhA:
undetectable		 4bqfA-2vjhA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
(Gloeobacter
violaceus) 		4 / 8 GLU A  25
SER A  26
ARG A  17
VAL A   8
 None
 1.39A 4capA-2vjhA:
undetectable
4capB-2vjhA:
undetectable		 4capA-2vjhA:
17.42
4capB-2vjhA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
(Gloeobacter
violaceus) 		4 / 8 GLU A  25
SER A  26
ARG A  17
VAL A   8
 None
 1.37A 4d32A-2vjhA:
undetectable
4d32B-2vjhA:
undetectable		 4d32A-2vjhA:
17.42
4d32B-2vjhA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		4 / 7 ALA B 140
ALA B 165
GLY B 166
ILE B  44
 PUB  B1050 ( 4.0A)
None
None
None
 0.66A 4eatA-2vjhB:
undetectable		 4eatA-2vjhB:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 LEU B  38
ASN A  30
ALA B  99
ALA A  12
VAL A   8
 PEB  B1158 (-4.2A)
None
None
None
None
 1.09A 4nkxC-2vjhB:
undetectable		 4nkxC-2vjhB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		3 / 3 ASP B  54
ASN B  47
SER B 132
 PUB  B1050 (-3.0A)
None
None
 0.86A 4obwA-2vjhB:
undetectable		 4obwA-2vjhB:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 ASN B 143
LEU B  90
ALA B  43
LEU B  97
GLY B 166
 None
 1.28A 4qckA-2vjhB:
undetectable		 4qckA-2vjhB:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
(Gloeobacter
violaceus) 		4 / 4 THR A   6
GLY A 103
ASP A 106
SER A   3
 None
 1.26A 4rfqA-2vjhA:
undetectable		 4rfqA-2vjhA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
(Gloeobacter
violaceus) 		4 / 8 GLU A  25
SER A  26
ARG A  17
VAL A   8
 None
 1.37A 4v3yA-2vjhA:
undetectable
4v3yB-2vjhA:
undetectable		 4v3yA-2vjhA:
17.42
4v3yB-2vjhA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 ASN B  63
CYH B  73
ARG B  78
CYH B  82
LEU B  66
 None
PEB  B1082 (-3.5A)
PEB  B1082 (-4.5A)
PEB  B1082 (-1.6A)
PEB  B1082 ( 4.7A)
 1.35A 5lsuA-2vjhB:
undetectable		 5lsuA-2vjhB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 2vjh PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		5 / 12 GLY B 121
ASN B  63
CYH B  73
CYH B  82
LEU B  66
 MEN  B  72 ( 4.5A)
None
PEB  B1082 (-3.5A)
PEB  B1082 (-1.6A)
PEB  B1082 ( 4.7A)
 1.36A 5lsuA-2vjhB:
undetectable		 5lsuA-2vjhB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus;
Gloeobacter
violaceus) 		3 / 3 TYR A  95
SER B  11
TRP A 108
 None
 0.74A 5n8jB-2vjhA:
undetectable		 5n8jB-2vjhA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus;
Gloeobacter
violaceus) 		3 / 3 TYR A  95
SER B  11
TRP A 108
 None
 0.76A 5n8jA-2vjhA:
undetectable		 5n8jA-2vjhA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus;
Gloeobacter
violaceus) 		3 / 3 TYR A  95
SER B  11
TRP A 108
 None
 0.72A 5n8jD-2vjhA:
undetectable		 5n8jD-2vjhA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2vjh PHYCOERYTHRIN ALPHA
CHAIN
PHYCOERYTHRIN BETA
SUBUNIT
(Gloeobacter
violaceus) 		4 / 7 VAL A  52
ARG A  91
TYR B  18
LEU A 105
 None
 1.07A 5umwB-2vjhA:
undetectable
5umwE-2vjhA:
undetectable		 5umwB-2vjhA:
19.53
5umwE-2vjhA:
19.53