SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_2 (RETINOIC ACID RECEPTOR, BETA)	2vjw	GAF FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	LEU A 247 PHE A 355 ARG A 238	None	0.80A	1xdkB-2vjwA: undetectable	1xdkB-2vjwA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_2 (RETINOIC ACID RECEPTOR, BETA)	2vjw	GAF FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	LEU A 247 PHE A 355 ARG A 238	None	0.80A	1xdkF-2vjwA: undetectable	1xdkF-2vjwA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BOG_C_DVAC59_0 (6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN)	2vjw	GAF FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	3 / 3	GLY A 315 GLY A 340 GLY A 338	None	0.39A	3bogC-2vjwA: undetectable	3bogC-2vjwA: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YPM_A_BO2A801_1 (LON PROTEASE)	2vjw	GAF FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	ALA A 250 THR A 253 THR A 248 GLY A 316 ALA A 341	None	1.17A	4ypmA-2vjwA: undetectable	4ypmA-2vjwA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7P_G_CHDG401_0 (BILE SALT HYDROLASE)	2vjw	GAF FAMILY PROTEIN (Mycolicibacteriu m smegmatis)	5 / 10	LEU A 323 ILE A 294 LEU A 254 LEU A 245 ALA A 244	None	1.25A	5y7pG-2vjwA: undetectable	5y7pG-2vjwA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XDK_B_9CRB600_2","RETINOIC ACID RECEPTOR, BETA","2vjw","GAF FAMILY PROTEIN","Mycolicibacterium smegmatis",3,"LEU A 247;PHE A 355;ARG A 238","None","0.80A","1xdkB-2vjwA:undetectable","1xdkB-2vjwA:19.32"],["1XDK_F_9CRF1600_2","RETINOIC ACID RECEPTOR, BETA","2vjw","GAF FAMILY PROTEIN","Mycolicibacterium smegmatis",3,"LEU A 247;PHE A 355;ARG A 238","None","0.80A","1xdkF-2vjwA:undetectable","1xdkF-2vjwA:19.32"],["3BOG_C_DVAC59_0","6.5 KDA GLYCINE-RICH ANTIFREEZE PROTEIN","2vjw","GAF FAMILY PROTEIN","Mycolicibacterium smegmatis",3,"GLY A 315;GLY A 340;GLY A 338","None","0.39A","3bogC-2vjwA:undetectable","3bogC-2vjwA:19.46"],["4YPM_A_BO2A801_1","LON PROTEASE","2vjw","GAF FAMILY PROTEIN","Mycolicibacterium smegmatis",5,"ALA A 250;THR A 253;THR A 248;GLY A 316;ALA A 341","None","1.17A","4ypmA-2vjwA:undetectable","4ypmA-2vjwA:21.57"],["5Y7P_G_CHDG401_0","BILE SALT HYDROLASE","2vjw","GAF FAMILY PROTEIN","Mycolicibacterium smegmatis",5,"LEU A 323;ILE A 294;LEU A 254;LEU A 245;ALA A 244","None","1.25A","5y7pG-2vjwA:undetectable","5y7pG-2vjwA:21.43"]]