SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vkg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MOG_A_RBFA200_1
(DODECIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		3 / 3 PHE A   3
TRP A  36
GLU A  38
 CF4  A1064 ( 4.7A)
CF4  A1064 (-3.3A)
MG  A1061 ( 4.0A)
 0.09A 1mogA-2vkgA:
13.6		 1mogA-2vkgA:
95.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		4 / 6 ARG A  50
ILE A  46
GLY A  47
ALA A  48
 None
 0.85A 1wmqA-2vkgA:
undetectable		 1wmqA-2vkgA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		4 / 6 ARG A  50
ILE A  46
GLY A  47
ALA A  48
 None
 0.85A 1wmqB-2vkgA:
undetectable		 1wmqB-2vkgA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		4 / 6 ARG A  50
ILE A  46
GLY A  47
ALA A  48
 None
 0.87A 1wpuA-2vkgA:
undetectable		 1wpuA-2vkgA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		4 / 6 ARG A  50
ILE A  46
GLY A  47
ALA A  48
 None
 0.86A 1wpuB-2vkgA:
undetectable		 1wpuB-2vkgA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		4 / 6 ARG A  50
ILE A  46
GLY A  47
ALA A  48
 None
 0.88A 1wrqB-2vkgA:
undetectable		 1wrqB-2vkgA:
18.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CC8_A_RBFA1067_1
(VNG1446H)		 2vkg DODECIN
(Halobacterium
salinarum) 		3 / 3 PHE A   3
VAL A  35
TRP A  36
 CF4  A1064 ( 4.7A)
CF4  A1064 (-4.5A)
CF4  A1064 (-3.3A)
 0.30A 2cc8A-2vkgA:
13.8		 2cc8A-2vkgA:
95.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CCB_A_RBFA1067_1
(VNG1446H)		 2vkg DODECIN
(Halobacterium
salinarum) 		3 / 3 PHE A   3
VAL A  35
TRP A  36
 CF4  A1064 ( 4.7A)
CF4  A1064 (-4.5A)
CF4  A1064 (-3.3A)
 0.30A 2ccbA-2vkgA:
13.9		 2ccbA-2vkgA:
95.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VX9_A_RBFA1064_1
(DODECIN)		 2vkg DODECIN
(Halobacterium
salinarum) 		3 / 3 PHE A   3
VAL A  35
TRP A  36
 CF4  A1064 ( 4.7A)
CF4  A1064 (-4.5A)
CF4  A1064 (-3.3A)
 0.29A 2vx9A-2vkgA:
13.5		 2vx9A-2vkgA:
96.88