SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vkn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXY_A_SAMA6734_0 (N-LYSINE METHYLTRANSFERASE SETD6)	2vkn	PROTEIN SSU81 (Saccharomyces cerevisiae)	5 / 12	VAL A 33 ALA A 43 ALA A 15 TYR A 13 PHE A 25	None	0.93A	3qxyA-2vknA: undetectable	3qxyA-2vknA: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXY_B_SAMB6735_0 (N-LYSINE METHYLTRANSFERASE SETD6 TRANSCRIPTION FACTOR P65)	2vkn	PROTEIN SSU81 (Saccharomyces cerevisiae)	5 / 11	VAL A 33 ALA A 43 ALA A 15 TYR A 13 PHE A 25	None	0.97A	3qxyB-2vknA: undetectable 3qxyQ-2vknA: undetectable	3qxyB-2vknA: 7.88 3qxyQ-2vknA: 17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_A_SAMA484_0 (N-LYSINE METHYLTRANSFERASE SETD6)	2vkn	PROTEIN SSU81 (Saccharomyces cerevisiae)	5 / 11	VAL A 33 ALA A 43 ALA A 15 TYR A 13 PHE A 25	None	0.94A	3rc0A-2vknA: undetectable	3rc0A-2vknA: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RC0_B_SAMB480_0 (N-LYSINE METHYLTRANSFERASE SETD6)	2vkn	PROTEIN SSU81 (Saccharomyces cerevisiae)	5 / 12	VAL A 33 ALA A 43 ALA A 15 TYR A 13 PHE A 25	None	0.92A	3rc0B-2vknA: undetectable	3rc0B-2vknA: 7.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3QXY_A_SAMA6734_0","N-LYSINE METHYLTRANSFERASE SETD6","2vkn","PROTEIN SSU81","Saccharomyces cerevisiae",5,"VAL A  33;ALA A  43;ALA A  15;TYR A  13;PHE A  25","None","0.93A","3qxyA-2vknA:undetectable","3qxyA-2vknA:7.88"],["3QXY_B_SAMB6735_0","N-LYSINE METHYLTRANSFERASE SETD6;TRANSCRIPTION FACTOR P65","2vkn","PROTEIN SSU81","Saccharomyces cerevisiae",5,"VAL A  33;ALA A  43;ALA A  15;TYR A  13;PHE A  25","None","0.97A","3qxyB-2vknA:undetectable;3qxyQ-2vknA:undetectable","3qxyB-2vknA:7.88;3qxyQ-2vknA:17.14"],["3RC0_A_SAMA484_0","N-LYSINE METHYLTRANSFERASE SETD6","2vkn","PROTEIN SSU81","Saccharomyces cerevisiae",5,"VAL A  33;ALA A  43;ALA A  15;TYR A  13;PHE A  25","None","0.94A","3rc0A-2vknA:undetectable","3rc0A-2vknA:7.88"],["3RC0_B_SAMB480_0","N-LYSINE METHYLTRANSFERASE SETD6","2vkn","PROTEIN SSU81","Saccharomyces cerevisiae",5,"VAL A  33;ALA A  43;ALA A  15;TYR A  13;PHE A  25","None","0.92A","3rc0B-2vknA:undetectable","3rc0B-2vknA:7.88"]]