SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		5 / 11 GLY A 235
VAL A 231
ILE A 197
ILE A 216
ILE A 262
 None
 0.95A 1n49B-2vl6A:
undetectable		 1n49B-2vl6A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		4 / 8 ARG A 211
LEU A 109
VAL A 233
VAL A 128
 None
 0.94A 2bdmA-2vl6A:
undetectable		 2bdmA-2vl6A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		4 / 7 THR A 234
VAL A 101
VAL A 106
ASP A 124
 None
 0.93A 2cppA-2vl6A:
undetectable		 2cppA-2vl6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		3 / 3 CYH A 171
CYH A 149
HIS A 144
 ZN  A1266 (-2.0A)
ZN  A1266 (-2.2A)
ZN  A1266 (-3.1A)
 0.71A 2iwkA-2vl6A:
undetectable		 2iwkA-2vl6A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		3 / 3 CYH A 171
CYH A 149
HIS A 144
 ZN  A1266 (-2.0A)
ZN  A1266 (-2.2A)
ZN  A1266 (-3.1A)
 0.74A 2iwkB-2vl6A:
undetectable		 2iwkB-2vl6A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		3 / 3 PRO A 168
GLU A 152
TYR A 142
 None
 0.80A 2zmbA-2vl6A:
undetectable		 2zmbA-2vl6A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		3 / 3 CYH A 171
CYH A 149
HIS A 144
 ZN  A1266 (-2.0A)
ZN  A1266 (-2.2A)
ZN  A1266 (-3.1A)
 0.60A 3dtuB-2vl6A:
undetectable		 3dtuB-2vl6A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		3 / 3 CYH A 171
CYH A 149
HIS A 144
 ZN  A1266 (-2.0A)
ZN  A1266 (-2.2A)
ZN  A1266 (-3.1A)
 0.57A 3dtuD-2vl6A:
undetectable		 3dtuD-2vl6A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		5 / 12 LEU A  37
ILE A  93
ILE A  82
TYR A  79
TYR A 138
 None
 1.09A 4a79A-2vl6A:
undetectable		 4a79A-2vl6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		5 / 12 LEU A  37
ILE A  93
ILE A  82
TYR A  79
TYR A 138
 None
 1.07A 4a79B-2vl6A:
undetectable		 4a79B-2vl6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		5 / 11 LEU A  37
ILE A  93
ILE A  82
TYR A  79
TYR A 138
 None
 1.11A 4a7aA-2vl6A:
undetectable		 4a7aA-2vl6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		5 / 12 LEU A  37
ILE A  93
ILE A  82
TYR A  79
TYR A 138
 None
 1.11A 4a7aB-2vl6A:
undetectable		 4a7aB-2vl6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2vl6 MINICHROMOSOME
MAINTENANCE PROTEIN
MCM
(Sulfolobus
solfataricus) 		4 / 8 THR A 234
VAL A 101
VAL A 106
ASP A 124
 None
 0.97A 4l4aA-2vl6A:
undetectable		 4l4aA-2vl6A:
20.62