SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 ARG A 170
VAL A  69
LEU A  67
ILE A 162
ALA A 166
 None
 1.04A 1cqeA-2vlcA:
undetectable		 1cqeA-2vlcA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 ARG A 170
VAL A  69
LEU A  67
ILE A 162
ALA A 166
 None
 1.04A 1cqeB-2vlcA:
undetectable		 1cqeB-2vlcA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 9 GLY A 113
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.26A 1mrgA-2vlcA:
30.6		 1mrgA-2vlcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 9 TYR A  75
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.84A 1mrgA-2vlcA:
30.6		 1mrgA-2vlcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 8 GLY A 113
TYR A 115
ILE A 162
GLU A 167
ARG A 170
 None
 0.16A 1mrjA-2vlcA:
30.9		 1mrjA-2vlcA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 8 TYR A  75
TYR A 115
GLU A 167
ARG A 170
 None
 0.89A 1mrjA-2vlcA:
30.9		 1mrjA-2vlcA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 ARG A 170
VAL A  69
LEU A  67
ILE A 162
ALA A 166
 None
 1.09A 2aylB-2vlcA:
undetectable		 2aylB-2vlcA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 8 SER A 146
LEU A  67
TYR A  79
LEU A 136
 None
 0.97A 2bfpB-2vlcA:
undetectable		 2bfpB-2vlcA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 ILE A  20
THR A  12
ALA A  11
VAL A  54
PHE A  19
 None
 1.48A 2gl0A-2vlcA:
undetectable
2gl0C-2vlcA:
undetectable		 2gl0A-2vlcA:
14.18
2gl0C-2vlcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 PHE A  19
ILE A  20
THR A  12
ALA A  11
VAL A  54
 None
 1.48A 2gl0D-2vlcA:
undetectable
2gl0E-2vlcA:
undetectable		 2gl0D-2vlcA:
14.18
2gl0E-2vlcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 11 ILE A  20
THR A  12
ALA A  11
VAL A  54
PHE A  19
 None
 1.48A 2gl0D-2vlcA:
undetectable
2gl0F-2vlcA:
undetectable		 2gl0D-2vlcA:
14.18
2gl0F-2vlcA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 ARG A 467
SER A 478
ILE A 488
ILE A 533
ALA A 411
 None
 0.97A 2j0dA-2vlcA:
undetectable		 2j0dA-2vlcA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 5 GLU A  32
PRO A  33
ILE A  36
GLY A  35
 None
 0.82A 2qeuA-2vlcA:
undetectable
2qeuC-2vlcA:
undetectable		 2qeuA-2vlcA:
14.50
2qeuC-2vlcA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 10 LEU A  23
ALA A 166
LEU A  67
VAL A  54
PHE A  19
 None
 1.14A 2w9hA-2vlcA:
undetectable		 2w9hA-2vlcA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 8 TYR A 410
SER A 393
GLN A 414
VAL A 503
 AS5  A1551 (-4.6A)
None
None
None
 1.25A 3b9lA-2vlcA:
undetectable		 3b9lA-2vlcA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 LEU A 118
TYR A 115
GLY A 113
SER A 114
LEU A  88
 None
 1.19A 3e23A-2vlcA:
undetectable		 3e23A-2vlcA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 11 LEU A  23
ALA A 166
LEU A  67
VAL A  54
PHE A  19
 None
 1.12A 3frbX-2vlcA:
undetectable		 3frbX-2vlcA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 5 VAL A  69
LEU A  67
ILE A 162
ALA A 166
 None
 0.84A 3n8yB-2vlcA:
undetectable		 3n8yB-2vlcA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 GLY A 415
GLY A 300
VAL A 391
GLY A 381
PHE A 377
 None
 1.07A 3sglA-2vlcA:
undetectable		 3sglA-2vlcA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 10 SER A 112
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.58A 3u6tA-2vlcA:
30.8		 3u6tA-2vlcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 10 TYR A  75
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.71A 3u6tA-2vlcA:
30.8		 3u6tA-2vlcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		3 / 3 GLN A 320
THR A 401
THR A 402
 None
 0.81A 4fufA-2vlcA:
undetectable		 4fufA-2vlcA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 7 GLU A 119
GLU A 128
GLU A 127
ARG A 126
 None
 1.18A 4mi4B-2vlcA:
undetectable
4mi4C-2vlcA:
undetectable		 4mi4B-2vlcA:
17.41
4mi4C-2vlcA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 5 TYR A  75
TYR A 115
ILE A 162
ARG A 170
 None
 0.61A 4o0oA-2vlcA:
30.8		 4o0oA-2vlcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O79_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 6 LYS A 539
LYS A 543
ARG A  24
ALA A  25
 None
 1.45A 4o79B-2vlcA:
0.0		 4o79B-2vlcA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 VAL A 233
ARG A 224
VAL A 240
LEU A 548
SER A 196
 None
 1.31A 4po0A-2vlcA:
undetectable		 4po0A-2vlcA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		3 / 3 GLU A 167
ALA A 168
PHE A 171
 None
 0.66A 4v1fC-2vlcA:
undetectable		 4v1fC-2vlcA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 4 ASN A 206
SER A 219
ALA A 207
VAL A 208
 None
 1.38A 4x1kC-2vlcA:
undetectable		 4x1kC-2vlcA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 9 GLY A 113
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.29A 4yp2B-2vlcA:
30.9		 4yp2B-2vlcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 9 TYR A  75
GLY A 113
ILE A 162
ALA A 166
ARG A 170
 None
 0.77A 4yp2B-2vlcA:
30.9		 4yp2B-2vlcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 7 ALA A 459
ARG A 301
GLY A 300
THR A 401
 None
 0.99A 5btdA-2vlcA:
undetectable
5btdC-2vlcA:
undetectable
5btdD-2vlcA:
undetectable		 5btdA-2vlcA:
22.43
5btdC-2vlcA:
22.43
5btdD-2vlcA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		6 / 9 GLY A 113
TYR A 115
ILE A 162
ALA A 166
GLU A 167
ARG A 170
 None
 0.27A 5cf9B-2vlcA:
30.9		 5cf9B-2vlcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 9 TYR A  75
GLY A 113
ILE A 162
ALA A 166
ARG A 170
 None
 0.74A 5cf9B-2vlcA:
30.9		 5cf9B-2vlcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		3 / 3 ASP A 238
VAL A 221
LEU A 204
 None
 0.65A 5e5jB-2vlcA:
undetectable		 5e5jB-2vlcA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		3 / 3 ASP A 286
PHE A 249
ARG A 252
 None
 0.76A 5yw0A-2vlcA:
undetectable		 5yw0A-2vlcA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 6 TYR A  75
VAL A  76
ILE A 162
GLU A 167
ARG A 170
 None
 0.67A 5z3jA-2vlcA:
33.8		 5z3jA-2vlcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 6 VAL A  76
TYR A 115
ILE A 162
GLU A 167
ARG A 170
 None
 0.29A 5z3jA-2vlcA:
33.8		 5z3jA-2vlcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		4 / 6 SER A 218
ASP A 291
GLN A 210
THR A 335
 None
 1.26A 6djzA-2vlcA:
undetectable		 6djzA-2vlcA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 GLY A 311
VAL A 330
ASP A 329
ILE A 362
LYS A 325
 None
 1.08A 6exiC-2vlcA:
undetectable
6exiD-2vlcA:
undetectable		 6exiC-2vlcA:
10.49
6exiD-2vlcA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III
(Cinnamomum
camphora) 		5 / 12 LYS A 325
GLY A 311
VAL A 330
ASP A 329
ILE A 362
 None
 1.11A 6exiC-2vlcA:
undetectable
6exiD-2vlcA:
undetectable		 6exiC-2vlcA:
10.49
6exiD-2vlcA:
10.49