SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2vm6 BCL-2-RELATED
PROTEIN A1
(Homo
sapiens) 		4 / 7 THR A 130
ILE A 134
GLY A 131
ILE A   9
 None
 0.79A 2y7wC-2vm6A:
undetectable		 2y7wC-2vm6A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2vm6 BCL-2-RELATED
PROTEIN A1
(Homo
sapiens) 		5 / 12 ILE A  84
GLY A  87
ALA A  41
VAL A  40
PHE A  95
 None
 1.09A 2yvlC-2vm6A:
undetectable		 2yvlC-2vm6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 2vm6 BCL-2-RELATED
PROTEIN A1
(Homo
sapiens) 		3 / 3 ARG A  68
GLU A  96
ASP A  15
 None
 0.83A 3g2oA-2vm6A:
undetectable		 3g2oA-2vm6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2vm6 BCL-2-RELATED
PROTEIN A1
(Homo
sapiens) 		4 / 6 THR A  33
GLU A 141
THR A 130
LEU A  12
 None
 0.89A 4pgfA-2vm6A:
undetectable		 4pgfA-2vm6A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2vm6 BCL-2-RELATED
PROTEIN A1
(Homo
sapiens) 		3 / 3 TYR A  16
ASP A  15
GLN A  38
 None
 0.94A 6g1pA-2vm6A:
undetectable		 6g1pA-2vm6A:
17.30