SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_B_CHDB1605_0 (FERROCHELATASE)	2vmb	GENERAL SECRETION PATHWAY PROTEIN F (Vibrio cholerae)	5 / 12	LEU A 146 LEU A 150 LEU A 105 VAL A 92 VAL A 112	None	1.20A	2hrcB-2vmbA: undetectable	2hrcB-2vmbA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I45_A_NIOA500_1 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN)	2vmb	GENERAL SECRETION PATHWAY PROTEIN F (Vibrio cholerae)	4 / 8	PHE A 129 SER A 121 LEU A 118 LEU A 75	None	0.91A	3i45A-2vmbA: undetectable	3i45A-2vmbA: 17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PUO_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	2vmb	GENERAL SECRETION PATHWAY PROTEIN F (Vibrio cholerae)	4 / 8	LEU A 118 VAL A 79 VAL A 149 LEU A 89	None	0.77A	4puoC-2vmbA: undetectable	4puoC-2vmbA: 11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	2vmb	GENERAL SECRETION PATHWAY PROTEIN F (Vibrio cholerae)	4 / 8	LEU A 118 VAL A 79 VAL A 149 LEU A 89	None	0.93A	4pwdA-2vmbA: undetectable	4pwdA-2vmbA: 11.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HRC_B_CHDB1605_0","FERROCHELATASE","2vmb","GENERAL SECRETION PATHWAY PROTEIN F","Vibrio cholerae",5,"LEU A 146;LEU A 150;LEU A 105;VAL A  92;VAL A 112","None","1.20A","2hrcB-2vmbA:undetectable","2hrcB-2vmbA:17.78"],["3I45_A_NIOA500_1","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN","2vmb","GENERAL SECRETION PATHWAY PROTEIN F","Vibrio cholerae",4,"PHE A 129;SER A 121;LEU A 118;LEU A  75","None","0.91A","3i45A-2vmbA:undetectable","3i45A-2vmbA:17.66"],["4PUO_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","2vmb","GENERAL SECRETION PATHWAY PROTEIN F","Vibrio cholerae",4,"LEU A 118;VAL A  79;VAL A 149;LEU A  89","None","0.77A","4puoC-2vmbA:undetectable","4puoC-2vmbA:11.87"],["4PWD_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","2vmb","GENERAL SECRETION PATHWAY PROTEIN F","Vibrio cholerae",4,"LEU A 118;VAL A  79;VAL A 149;LEU A  89","None","0.93A","4pwdA-2vmbA:undetectable","4pwdA-2vmbA:11.87"]]