SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2vmd DISCOIDIN-2
(Dictyostelium
discoideum) 		3 / 3 TYR A  24
ARG A  81
HIS A  84
 EDO  A 504 ( 3.8A)
EDO  A 504 (-4.0A)
None
 1.20A 4fubA-2vmdA:
undetectable		 4fubA-2vmdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 2vmd DISCOIDIN-2
(Dictyostelium
discoideum) 		5 / 12 CYH A  10
LEU A  11
THR A  96
ALA A 153
ILE A 134
 None
 1.21A 5nm5B-2vmdA:
undetectable		 5nm5B-2vmdA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 2vmd DISCOIDIN-2
(Dictyostelium
discoideum) 		5 / 12 CYH A  10
LEU A  11
THR A  96
ALA A 153
ILE A 134
 None
 1.21A 5xiwD-2vmdA:
undetectable		 5xiwD-2vmdA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 2vmd DISCOIDIN-2
(Dictyostelium
discoideum) 		5 / 12 PHE A  73
TYR A 152
ALA A  12
ILE A  63
LEU A  16
 None
 1.22A 6aybA-2vmdA:
undetectable		 6aybA-2vmdA:
21.71