SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		5 / 12 TYR A 962
LEU A1026
ILE A 952
GLY A1045
ALA A1047
 None
 1.02A 1eqhB-2vmhA:
undetectable		 1eqhB-2vmhA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		5 / 12 LEU A1049
THR A1050
GLU A 905
ILE A 952
GLY A 951
 None
 0.86A 1qknA-2vmhA:
undetectable		 1qknA-2vmhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		4 / 7 LYS A1000
SER A 991
VAL A1029
LYS A1031
 None
 1.02A 2j9cA-2vmhA:
undetectable
2j9cB-2vmhA:
undetectable
2j9cC-2vmhA:
undetectable		 2j9cA-2vmhA:
22.58
2j9cB-2vmhA:
22.58
2j9cC-2vmhA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		4 / 8 ALA A1047
THR A 954
LYS A 927
ASP A 928
 None
 1.09A 2kotB-2vmhA:
undetectable		 2kotB-2vmhA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		4 / 8 ALA A 918
THR A 975
VAL A1016
PHE A 973
 None
 1.03A 4ltwA-2vmhA:
undetectable		 4ltwA-2vmhA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		4 / 6 GLY A1045
ASP A 928
ASP A 980
ASP A1046
 None
 0.90A 4uckB-2vmhA:
undetectable		 4uckB-2vmhA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2vmh FIBRONECTIN TYPE III
DOMAIN PROTEIN
(Clostridium
perfringens) 		5 / 11 LEU A 964
LEU A1026
LEU A1049
GLU A 912
LEU A 910
 None
 1.17A 4wg0F-2vmhA:
undetectable
4wg0G-2vmhA:
undetectable
4wg0H-2vmhA:
undetectable		 4wg0F-2vmhA:
7.46
4wg0G-2vmhA:
7.46
4wg0H-2vmhA:
7.46