SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vmj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.67A 1oe1A-2vmjA:
52.3
1oe1A-2vmjA:
96.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 ASP A  92
HIS A  94
HIS A 129
ZN  A1328 (-4.1A)
ZN  A1328 (-3.3A)
ZN  A1328 (-3.3A)
0.17A 1oe1A-2vmjA:
52.3
1oe1A-2vmjA:
96.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 5 CYH A 130
PRO A 132
HIS A 133
MET A 136
ZN  A1330 (-2.1A)
None
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.84A 1oe2A-2vmjA:
43.3
1oe2A-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 5 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.66A 1oe2A-2vmjA:
43.3
1oe2A-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.68A 1oe3A-2vmjA:
51.9
1oe3A-2vmjA:
96.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 ASP A  92
HIS A  94
HIS A 129
ZN  A1328 (-4.1A)
ZN  A1328 (-3.3A)
ZN  A1328 (-3.3A)
0.19A 1oe3A-2vmjA:
51.9
1oe3A-2vmjA:
96.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 7 THR A 280
TYR A 279
TYR A 287
LEU A 242
None
1.13A 1qzrA-2vmjA:
undetectable
1qzrA-2vmjA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 7 THR A 280
TYR A 279
TYR A 287
LEU A 242
None
1.13A 1qzrB-2vmjA:
undetectable
1qzrB-2vmjA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 8 GLY A 271
THR A 139
ILE A 269
SER A 273
None
0.97A 2a8tB-2vmjA:
undetectable
2a8tB-2vmjA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.65A 2fqdA-2vmjA:
18.3
2fqdA-2vmjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.69A 2fqeA-2vmjA:
18.4
2fqeA-2vmjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.75A 2fqfA-2vmjA:
18.3
2fqfA-2vmjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.73A 2fqgA-2vmjA:
18.3
2fqgA-2vmjA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 PRO A 260
THR A 253
GLY A 275
THR A 125
LEU A 148
None
1.19A 2uvnA-2vmjA:
undetectable
2uvnA-2vmjA:
24.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.67A 2xxgA-2vmjA:
52.7
2xxgA-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 ASP A  92
HIS A  94
HIS A 129
ZN  A1328 (-4.1A)
ZN  A1328 (-3.3A)
ZN  A1328 (-3.3A)
0.16A 2xxgA-2vmjA:
52.7
2xxgA-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 5 CYH A 130
PRO A 132
HIS A 133
MET A 136
ZN  A1330 (-2.1A)
None
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.89A 2xxgC-2vmjA:
52.7
2xxgC-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 5 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.71A 2xxgC-2vmjA:
52.7
2xxgC-2vmjA:
95.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 ASP A  92
HIS A  94
HIS A 129
ZN  A1328 (-4.1A)
ZN  A1328 (-3.3A)
ZN  A1328 (-3.3A)
0.14A 2xxgC-2vmjA:
52.7
2xxgC-2vmjA:
95.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 7 GLY A 245
ASP A 263
TYR A 279
ARG A 262
None
1.23A 3arrA-2vmjA:
undetectable
3arrA-2vmjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 7 GLY A 245
ASP A 263
TYR A 279
ARG A 262
None
1.20A 3aruA-2vmjA:
undetectable
3aruA-2vmjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 8 PHE A 118
PHE A 126
ASP A  92
GLY A 101
None
None
ZN  A1328 (-4.1A)
None
0.85A 3c0zB-2vmjA:
undetectable
3c0zB-2vmjA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 GLU A 166
HIS A 231
THR A 238
None
0.78A 3hkuA-2vmjA:
undetectable
3hkuA-2vmjA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 11 ALA A  99
GLY A  98
THR A  97
ALA A  96
ASP A 121
None
1.24A 3mg0H-2vmjA:
undetectable
3mg0I-2vmjA:
undetectable
3mg0H-2vmjA:
21.99
3mg0I-2vmjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 HIS A 231
SER A 137
ASN A 207
None
0.76A 3s8pB-2vmjA:
undetectable
3s8pB-2vmjA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 5 HIS A 231
SER A 232
SER A 273
VAL A 127
None
1.45A 4a99D-2vmjA:
undetectable
4a99D-2vmjA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 4 HIS A  89
CYH A 130
HIS A 133
MET A 136
ZN  A1330 (-3.6A)
ZN  A1330 (-2.1A)
ZN  A1330 (-3.4A)
ZN  A1330 (-3.5A)
0.74A 4ef3A-2vmjA:
18.3
4ef3A-2vmjA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 GLY A  64
LEU A  67
HIS A  20
MET A  37
VAL A  11
None
1.45A 4okxA-2vmjA:
undetectable
4okxA-2vmjA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 GLY A 254
ALA A 276
TYR A 158
PHE A 256
SER A 123
None
1.13A 4pb1A-2vmjA:
undetectable
4pb1A-2vmjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 GLY A 254
ALA A 276
TYR A 158
PHE A 256
SER A 123
None
1.16A 4pd9A-2vmjA:
undetectable
4pd9A-2vmjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
3 / 3 HIS A 231
SER A 137
ASN A 207
None
0.81A 5cprB-2vmjA:
undetectable
5cprB-2vmjA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 GLY A 275
HIS A  22
LEU A 140
LEU A 148
TYR A 158
None
1.46A 5ji0D-2vmjA:
undetectable
5ji0D-2vmjA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 GLY A 165
ILE A 164
THR A 139
VAL A 127
LEU A 219
None
1.04A 5nz0A-2vmjA:
undetectable
5nz0A-2vmjA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
5 / 12 MET A  44
LEU A  53
VAL A 210
VAL A 205
THR A 214
None
None
EPE  A1331 ( 4.6A)
None
None
1.36A 6b50A-2vmjA:
undetectable
6b50A-2vmjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
2vmj DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE

(Achromobacter
xylosoxidans)
4 / 7 GLY A 124
THR A 125
PHE A 126
ARG A 270
None
0.86A 6jnhA-2vmjA:
undetectable
6jnhA-2vmjA:
22.08