SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 9 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.34A 1bkfA-2vn1A:
19.3		 1bkfA-2vn1A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.59A 1c9hA-2vn1A:
19.3		 1c9hA-2vn1A:
37.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.44A 1fapA-2vn1A:
19.7		 1fapA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 TYR A  44
PHE A  65
GLU A  73
VAL A  74
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
None
 1.02A 1fapA-2vn1A:
19.7		 1fapA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.44A 1fkbA-2vn1A:
19.8		 1fkbA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 12 TYR A  44
PHE A  65
GLU A  73
VAL A  74
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
None
 1.04A 1fkbA-2vn1A:
19.8		 1fkbA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.40A 1fkfA-2vn1A:
19.3		 1fkfA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.42A 1fkjA-2vn1A:
19.3		 1fkjA-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.44A 1fklA-2vn1A:
19.8		 1fklA-2vn1A:
41.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		6 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
None
 1.23A 1fklA-2vn1A:
19.8		 1fklA-2vn1A:
41.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
GLY A  72
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.33A 1pbkA-2vn1A:
18.1		 1pbkA-2vn1A:
35.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 9 TYR A  44
ASP A  56
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.49A 1q6iA-2vn1A:
16.7		 1q6iA-2vn1A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 10 TYR A  44
ASP A  56
ARG A  61
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.63A 1q6iB-2vn1A:
16.5		 1q6iB-2vn1A:
23.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.37A 1tcoC-2vn1A:
19.4		 1tcoC-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.28A 1yatA-2vn1A:
20.8		 1yatA-2vn1A:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
ASP A  56
PHE A  65
GLU A  73
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
None
 1.36A 2dg3A-2vn1A:
19.8		 2dg3A-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.46A 2dg3A-2vn1A:
19.8		 2dg3A-2vn1A:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 11 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.44A 2dg4A-2vn1A:
19.3		 2dg4A-2vn1A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
PHE A  65
GLU A  73
VAL A  74
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
None
 1.04A 2dg4A-2vn1A:
19.3		 2dg4A-2vn1A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 11 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.55A 2dg9A-2vn1A:
19.4		 2dg9A-2vn1A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
PHE A  65
GLU A  73
VAL A  74
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
None
 1.16A 2dg9A-2vn1A:
19.4		 2dg9A-2vn1A:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.39A 2fkeA-2vn1A:
19.4		 2fkeA-2vn1A:
40.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		6 / 11 TYR A  44
PHE A  55
ASP A  56
VAL A  74
ILE A  75
TRP A  78
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.5A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
 0.76A 2vcdA-2vn1A:
14.6		 2vcdA-2vn1A:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
VAL A  74
ILE A  75
TRP A  78
TYR A 101
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
 0.75A 2vcdA-2vn1A:
14.6		 2vcdA-2vn1A:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjA-2vn1A:
undetectable		 3fhjA-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjB-2vn1A:
undetectable		 3fhjB-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjC-2vn1A:
undetectable		 3fhjC-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjD-2vn1A:
undetectable		 3fhjD-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjE-2vn1A:
undetectable		 3fhjE-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fhjF-2vn1A:
undetectable		 3fhjF-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.09A 3fi0A-2vn1A:
undetectable		 3fi0A-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.06A 3fi0C-2vn1A:
undetectable		 3fi0C-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fi0D-2vn1A:
undetectable		 3fi0D-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.12A 3fi0F-2vn1A:
undetectable		 3fi0F-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fi0H-2vn1A:
undetectable		 3fi0H-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 8 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fi0I-2vn1A:
undetectable		 3fi0I-2vn1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.10A 3fi0J-2vn1A:
undetectable		 3fi0J-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.12A 3fi0K-2vn1A:
undetectable		 3fi0K-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.13A 3fi0L-2vn1A:
undetectable		 3fi0L-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.08A 3fi0M-2vn1A:
undetectable		 3fi0M-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.10A 3fi0N-2vn1A:
undetectable		 3fi0N-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.10A 3fi0O-2vn1A:
undetectable		 3fi0O-2vn1A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 9 VAL A  74
ASP A  79
ILE A  80
VAL A  18
VAL A  93
 FK5  A 501 (-3.5A)
None
None
None
None
 1.07A 3fi0R-2vn1A:
undetectable		 3fi0R-2vn1A:
22.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.44A 3ihzA-2vn1A:
24.1		 3ihzA-2vn1A:
80.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 8 TYR A  44
PHE A  65
TRP A  78
TYR A 101
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
 0.40A 3ihzB-2vn1A:
24.1		 3ihzB-2vn1A:
80.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 8 TYR A  44
TRP A  78
TYR A 101
GLY A 107
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
None
 0.80A 3ihzB-2vn1A:
24.1		 3ihzB-2vn1A:
80.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 10 TYR A  44
ASP A  56
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.27A 3kz7A-2vn1A:
18.4		 3kz7A-2vn1A:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.45A 3o5rA-2vn1A:
21.5		 3o5rA-2vn1A:
48.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.32A 3uf8A-2vn1A:
20.3		 3uf8A-2vn1A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.35A 3uqaA-2vn1A:
20.1		 3uqaA-2vn1A:
29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 8 TYR A  44
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.27A 3uqbA-2vn1A:
19.8		 3uqbA-2vn1A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.28A 3vawA-2vn1A:
19.5		 3vawA-2vn1A:
29.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.49A 4drhA-2vn1A:
19.8		 4drhA-2vn1A:
46.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.48A 4drhD-2vn1A:
19.9		 4drhD-2vn1A:
46.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 11 TYR A  44
ASP A  56
ARG A  61
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.68A 4driA-2vn1A:
21.9		 4driA-2vn1A:
46.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.35A 4driA-2vn1A:
21.9		 4driA-2vn1A:
46.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.55A 4drjA-2vn1A:
21.3		 4drjA-2vn1A:
39.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.56A 4dz2A-2vn1A:
20.2
4dz2B-2vn1A:
20.3		 4dz2A-2vn1A:
40.94
4dz2B-2vn1A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.55A 4dz2A-2vn1A:
20.2
4dz2B-2vn1A:
20.3		 4dz2A-2vn1A:
40.94
4dz2B-2vn1A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.43A 4dz3A-2vn1A:
20.1		 4dz3A-2vn1A:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.28A 4dz3B-2vn1A:
20.2		 4dz3B-2vn1A:
40.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		4 / 7 SER A  50
GLY A 100
GLY A 105
GLU A 104
 None
 0.96A 4koeA-2vn1A:
undetectable
4koeB-2vn1A:
undetectable
4koeD-2vn1A:
undetectable		 4koeA-2vn1A:
14.66
4koeB-2vn1A:
14.66
4koeD-2vn1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 10 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.34A 4laxA-2vn1A:
21.7		 4laxA-2vn1A:
22.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.26A 4nnrA-2vn1A:
16.1
4nnrB-2vn1A:
16.0		 4nnrA-2vn1A:
38.03
4nnrB-2vn1A:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 10 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.23A 4nnrB-2vn1A:
16.0		 4nnrB-2vn1A:
38.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 TYR A  44
ASP A  56
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.36A 4odoA-2vn1A:
11.9		 4odoA-2vn1A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 TYR A  44
ASP A  56
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.36A 4odoB-2vn1A:
11.6		 4odoB-2vn1A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 10 TYR A  44
ASP A  56
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.36A 4odoC-2vn1A:
11.5		 4odoC-2vn1A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		6 / 12 TYR A  44
ASP A  56
ILE A  75
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.42A 4odrA-2vn1A:
13.1
4odrB-2vn1A:
13.3		 4odrA-2vn1A:
23.36
4odrB-2vn1A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		5 / 11 TYR A  44
ASP A  56
ILE A  75
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.35A 4odrA-2vn1A:
13.1
4odrB-2vn1A:
13.3		 4odrA-2vn1A:
23.36
4odrB-2vn1A:
23.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.45A 4qt2A-2vn1A:
24.2		 4qt2A-2vn1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.53A 4qt3A-2vn1A:
24.0		 4qt3A-2vn1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 12 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.48A 5b8iC-2vn1A:
18.4		 5b8iC-2vn1A:
36.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 11 TYR A  44
ASP A  56
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.43A 5d75A-2vn1A:
18.7		 5d75A-2vn1A:
36.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 11 TYR A  44
ASP A  56
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.32A 5gpgA-2vn1A:
19.0		 5gpgA-2vn1A:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 12 TYR A  44
ASP A  56
PHE A  65
GLU A  73
VAL A  74
ILE A  75
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.53A 5hkgA-2vn1A:
19.5		 5hkgA-2vn1A:
37.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.27A 5huaA-2vn1A:
21.0		 5huaA-2vn1A:
39.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
 0.70A 5hw8A-2vn1A:
17.4
5hw8D-2vn1A:
17.6		 5hw8A-2vn1A:
33.09
5hw8D-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.59A 5hw8B-2vn1A:
17.6		 5hw8B-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 10 TYR A  44
ASP A  56
ARG A  61
VAL A  74
ILE A  75
TRP A  78
TYR A 101
LEU A 116
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.60A 5hw8C-2vn1A:
17.5
5hw8H-2vn1A:
14.5		 5hw8C-2vn1A:
33.09
5hw8H-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.48A 5hw8D-2vn1A:
17.6		 5hw8D-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.50A 5hw8E-2vn1A:
17.6		 5hw8E-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		8 / 12 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
FK5  A 501 (-4.8A)
 0.45A 5hw8B-2vn1A:
17.6
5hw8F-2vn1A:
14.5
5hw8G-2vn1A:
17.4		 5hw8B-2vn1A:
33.09
5hw8F-2vn1A:
33.09
5hw8G-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		9 / 11 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.45A 5hw8G-2vn1A:
17.4		 5hw8G-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		7 / 8 TYR A  44
ASP A  56
PHE A  65
VAL A  74
ILE A  75
TRP A  78
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.8A)
 0.58A 5hw8H-2vn1A:
14.5		 5hw8H-2vn1A:
33.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 11 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.35A 5hwcA-2vn1A:
19.2		 5hwcA-2vn1A:
41.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		4 / 8 ASP A  56
TYR A  44
SER A  84
VAL A  93
 FK5  A 501 (-3.4A)
FK5  A 501 (-4.1A)
None
None
 0.92A 6giqL-2vn1A:
undetectable
6giqP-2vn1A:
undetectable
6giqT-2vn1A:
undetectable		 6giqL-2vn1A:
15.23
6giqP-2vn1A:
21.80
6giqT-2vn1A:
19.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 12 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.48A 6mkeA-2vn1A:
21.7
6mkeD-2vn1A:
21.5		 6mkeA-2vn1A:
40.96
6mkeD-2vn1A:
40.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 12 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.48A 6mkeB-2vn1A:
21.8
6mkeC-2vn1A:
21.5		 6mkeB-2vn1A:
40.96
6mkeC-2vn1A:
40.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.36A 6mkeC-2vn1A:
21.5		 6mkeC-2vn1A:
40.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2vn1 70 KDA
PEPTIDYLPROLYL
ISOMERASE
(Plasmodium
falciparum) 		10 / 10 TYR A  44
ASP A  56
ARG A  61
PHE A  65
VAL A  74
ILE A  75
TRP A  78
TYR A 101
ILE A 110
PHE A 118
 FK5  A 501 (-4.1A)
FK5  A 501 (-3.4A)
FK5  A 501 (-3.9A)
FK5  A 501 (-4.1A)
FK5  A 501 (-3.5A)
FK5  A 501 (-4.3A)
FK5  A 501 (-3.3A)
FK5  A 501 (-4.7A)
None
FK5  A 501 (-4.8A)
 0.35A 6mkeD-2vn1A:
21.5		 6mkeD-2vn1A:
40.96