SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		12 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 180
ARG A 309
TYR A 315
TRP A 321
GLU A 404
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
BTB  A 620 (-4.0A)
 0.27A 1agmA-2vn7A:
62.4		 1agmA-2vn7A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_2
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 4 TRP A 178
GLU A 179
LEU A 419
TRP A 421
 None
BTB  A 620 (-3.6A)
None
None
 0.37A 1agmA-2vn7A:
62.4		 1agmA-2vn7A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		12 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 180
ARG A 309
TYR A 315
TRP A 321
GLU A 404
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
BTB  A 620 (-4.0A)
 0.27A 1agmA-2vn7A:
62.4		 1agmA-2vn7A:
47.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 TRP A 178
GLU A 179
LEU A 419
TRP A 421
 None
BTB  A 620 (-3.6A)
None
None
 0.37A 1agmA-2vn7A:
62.4		 1agmA-2vn7A:
47.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 TRP A 525
LYS A 560
TRP A 572
ASN A 577
 None
 0.39A 1dedA-2vn7A:
11.7		 1dedA-2vn7A:
22.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		11 / 12 TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 179
GLU A 180
TYR A 315
TRP A 321
GLU A 404
 BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
BTB  A 620 (-3.6A)
None
BTB  A 620 ( 4.9A)
None
BTB  A 620 (-4.0A)
 0.29A 1gahA-2vn7A:
62.4		 1gahA-2vn7A:
47.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 6 ALA A  38
TRP A 178
ARG A 309
LEU A 419
TRP A 421
 BTB  A 620 ( 3.8A)
None
BTB  A 620 (-3.6A)
None
None
 0.38A 1gahA-2vn7A:
62.4		 1gahA-2vn7A:
47.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 9 PRO A 107
THR A  52
GLY A 127
PHE A 109
GLY A 103
 None
 1.30A 1h4oC-2vn7A:
undetectable
1h4oD-2vn7A:
undetectable		 1h4oC-2vn7A:
12.79
1h4oD-2vn7A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 ARG A 309
GLY A 318
ASP A 313
TYR A 293
 BTB  A 620 (-3.6A)
None
None
None
 1.29A 1kf6M-2vn7A:
undetectable
1kf6N-2vn7A:
undetectable		 1kf6M-2vn7A:
21.94
1kf6N-2vn7A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 135
SER A 139
LEU A 142
ILE A 158
SER A 152
 None
 1.14A 1lbcA-2vn7A:
undetectable
1lbcC-2vn7A:
undetectable		 1lbcA-2vn7A:
18.80
1lbcC-2vn7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 ILE A 158
SER A 152
LEU A 135
SER A 139
LEU A 142
 None
 1.09A 1lbcA-2vn7A:
undetectable
1lbcC-2vn7A:
undetectable		 1lbcA-2vn7A:
18.80
1lbcC-2vn7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		9 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
GLU A 180
ARG A 309
TYR A 315
TRP A 421
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
 0.44A 1lf9A-2vn7A:
6.9		 1lf9A-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 ALA A  38
TYR A  47
TRP A 120
GLU A 180
TYR A 315
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
None
None
BTB  A 620 ( 4.9A)
 0.99A 1lf9A-2vn7A:
6.9		 1lf9A-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 4 TRP A 178
GLU A 179
TRP A 321
LEU A 419
 None
BTB  A 620 (-3.6A)
None
None
 0.27A 1lf9A-2vn7A:
6.9		 1lf9A-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		9 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
GLU A 180
ARG A 309
TYR A 315
TRP A 321
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
 0.48A 1lf9B-2vn7A:
6.8		 1lf9B-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		6 / 12 ALA A  38
TYR A  47
TRP A 120
GLU A 180
TYR A 315
TRP A 321
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
None
None
BTB  A 620 ( 4.9A)
None
 1.01A 1lf9B-2vn7A:
6.8		 1lf9B-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 GLN A 124
TRP A 120
GLU A 180
TYR A 315
TRP A 321
 None
None
None
BTB  A 620 ( 4.9A)
None
 1.31A 1lf9B-2vn7A:
6.8		 1lf9B-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		6 / 12 TRP A  51
GLN A 124
GLU A 180
ARG A 309
TYR A 315
TRP A 321
 BTB  A 620 (-3.8A)
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
 1.44A 1lf9B-2vn7A:
6.8		 1lf9B-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_2
(GLUCOAMYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 4 TRP A 178
GLU A 179
LEU A 419
TRP A 421
 None
BTB  A 620 (-3.6A)
None
None
 0.45A 1lf9B-2vn7A:
6.8		 1lf9B-2vn7A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 GLY A 105
GLU A 106
GLY A 103
GLY A  96
GLY A 174
 None
 0.92A 1n2xB-2vn7A:
undetectable		 1n2xB-2vn7A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 ASP A 162
LEU A 104
ALA A 132
LEU A 135
 None
 1.05A 1nh8A-2vn7A:
undetectable		 1nh8A-2vn7A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 LEU A  57
ALA A 134
ILE A 133
GLY A 127
 None
 0.82A 1sv9A-2vn7A:
undetectable		 1sv9A-2vn7A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		9 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
GLU A 180
ARG A 309
TYR A 315
TRP A 321
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
 0.57A 1ulvA-2vn7A:
30.6		 1ulvA-2vn7A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 GLN A 124
GLU A 179
LEU A 323
TRP A 321
 None
BTB  A 620 (-3.6A)
None
None
 1.47A 1ulvA-2vn7A:
30.6		 1ulvA-2vn7A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 TRP A 178
GLU A 179
LEU A 419
TRP A 421
 None
BTB  A 620 (-3.6A)
None
None
 0.40A 1ulvA-2vn7A:
30.6		 1ulvA-2vn7A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 10 LEU A 130
ALA A 132
ILE A 133
VAL A 166
ALA A 167
 None
 1.17A 1xp0A-2vn7A:
1.7		 1xp0A-2vn7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		3 / 3 ALA A 190
THR A 259
PHE A 227
 None
 0.72A 2c6nB-2vn7A:
undetectable		 2c6nB-2vn7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		12 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 180
ARG A 309
TYR A 315
TRP A 321
GLU A 404
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
BTB  A 620 (-4.0A)
 0.35A 2f6dA-2vn7A:
45.4		 2f6dA-2vn7A:
29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_2
(GLUCOAMYLASE GLU1)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 4 TRP A 178
GLU A 179
LEU A 419
TRP A 421
 None
BTB  A 620 (-3.6A)
None
None
 0.29A 2f6dA-2vn7A:
45.4		 2f6dA-2vn7A:
29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 ARG A 226
THR A 188
VAL A 189
GLN A 192
LEU A 221
 None
 1.26A 2fj1A-2vn7A:
undetectable		 2fj1A-2vn7A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		3 / 3 ALA A  84
GLY A  22
SER A  55
 None
 0.55A 2ivuA-2vn7A:
undetectable		 2ivuA-2vn7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 HIS A 418
ASN A  16
ILE A  12
ASP A 399
 None
 1.07A 2v57A-2vn7A:
undetectable		 2v57A-2vn7A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 HIS A 418
ASN A  16
ILE A  12
ASP A 399
 None
 1.07A 2v57C-2vn7A:
undetectable		 2v57C-2vn7A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 THR A  10
SER A 425
LEU A 427
THR A 430
 None
 0.96A 3deuB-2vn7A:
undetectable		 3deuB-2vn7A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_A_CYZA265_1
(GLUTAMATE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 11 LEU A 135
SER A 139
LEU A 142
ILE A 158
SER A 152
 None
 1.12A 3h6tA-2vn7A:
undetectable
3h6tC-2vn7A:
undetectable		 3h6tA-2vn7A:
18.80
3h6tC-2vn7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H6T_C_CYZC265_1
(GLUTAMATE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 11 ILE A 158
SER A 152
LEU A 135
SER A 139
LEU A 142
 None
 1.11A 3h6tA-2vn7A:
undetectable
3h6tC-2vn7A:
undetectable		 3h6tA-2vn7A:
18.80
3h6tC-2vn7A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_B_TRUB800_1
(GLUTAMATE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 135
SER A 139
LEU A 142
ILE A 158
SER A 152
 None
 1.11A 3iltB-2vn7A:
undetectable
3iltE-2vn7A:
undetectable		 3iltB-2vn7A:
17.72
3iltE-2vn7A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 10 ILE A 158
SER A 152
LEU A 135
SER A 139
LEU A 142
 None
 1.11A 3iltB-2vn7A:
undetectable
3iltE-2vn7A:
undetectable		 3iltB-2vn7A:
17.72
3iltE-2vn7A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 TYR A  70
GLN A  75
ILE A 155
PHE A  66
 None
 1.22A 3ls4L-2vn7A:
2.9		 3ls4L-2vn7A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 PHE A 354
ILE A 345
ALA A 380
VAL A 362
 None
 0.90A 3me6B-2vn7A:
undetectable		 3me6B-2vn7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		6 / 11 ALA A 521
VAL A 549
ALA A 516
GLY A 517
SER A 526
ASP A 555
 None
 0.99A 3mg0K-2vn7A:
undetectable
3mg0L-2vn7A:
undetectable		 3mg0K-2vn7A:
16.69
3mg0L-2vn7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		6 / 12 ALA A 521
VAL A 549
ALA A 516
GLY A 517
SER A 526
ASP A 555
 None
 1.00A 3mg0Y-2vn7A:
undetectable
3mg0Z-2vn7A:
undetectable		 3mg0Y-2vn7A:
16.69
3mg0Z-2vn7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		6 / 11 GLU A 404
TYR A 322
GLY A 308
ILE A 307
ALA A 306
ASP A 313
 BTB  A 620 (-4.0A)
None
None
None
None
None
 1.29A 3nmuB-2vn7A:
2.4
3nmuJ-2vn7A:
undetectable		 3nmuB-2vn7A:
21.17
3nmuJ-2vn7A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 177
PHE A 109
PHE A 187
ILE A 133
ALA A 132
 None
 1.18A 3nxuB-2vn7A:
undetectable		 3nxuB-2vn7A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ALA A 278
SER A 256
VAL A 253
LEU A 282
 None
 0.83A 3o14A-2vn7A:
undetectable		 3o14A-2vn7A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 533
VAL A 515
THR A 579
LEU A 551
VAL A 549
 None
None
MAN  A 608 ( 2.4A)
None
None
 1.24A 3sp9B-2vn7A:
undetectable		 3sp9B-2vn7A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 358
PHE A 354
LEU A 282
GLY A 387
LEU A 389
 None
 1.34A 3tbgA-2vn7A:
undetectable		 3tbgA-2vn7A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 LEU A 358
PHE A 354
LEU A 282
GLY A 387
LEU A 389
 None
 1.34A 3tbgC-2vn7A:
undetectable		 3tbgC-2vn7A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 10 SER A 496
LEU A 522
VAL A 515
PHE A 501
VAL A 557
 None
 1.27A 3u9fE-2vn7A:
undetectable		 3u9fE-2vn7A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 SER A 496
LEU A 522
VAL A 515
PHE A 501
VAL A 557
 None
 1.18A 3u9fH-2vn7A:
undetectable
3u9fI-2vn7A:
undetectable		 3u9fH-2vn7A:
14.50
3u9fI-2vn7A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 9 SER A 496
LEU A 522
VAL A 515
PHE A 501
VAL A 557
 None
 1.24A 3u9fP-2vn7A:
undetectable		 3u9fP-2vn7A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.15A 4feuB-2vn7A:
undetectable		 4feuB-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 0.88A 4feuD-2vn7A:
undetectable		 4feuD-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 0.92A 4fevB-2vn7A:
undetectable		 4fevB-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.20A 4fevD-2vn7A:
undetectable		 4fevD-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.21A 4fevF-2vn7A:
undetectable		 4fevF-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 0.93A 4fewB-2vn7A:
undetectable		 4fewB-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.21A 4fewD-2vn7A:
undetectable		 4fewD-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.21A 4fewF-2vn7A:
undetectable		 4fewF-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 0.92A 4gkhD-2vn7A:
undetectable		 4gkhD-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.21A 4gkhG-2vn7A:
undetectable		 4gkhG-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASP A 313
ASP A 176
GLU A 404
ASP A 249
 None
None
BTB  A 620 (-4.0A)
None
 1.21A 4gkiA-2vn7A:
undetectable		 4gkiA-2vn7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 ASN A  16
ALA A  13
PRO A  11
LEU A 427
 None
 0.91A 4jjkA-2vn7A:
undetectable		 4jjkA-2vn7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		3 / 3 ARG A  53
ASP A 249
ASP A 236
 BTB  A 620 (-3.7A)
None
CA  A 650 (-2.2A)
 0.88A 4kicB-2vn7A:
undetectable		 4kicB-2vn7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 GLY A 174
SER A 185
SER A 102
ASP A 126
PRO A 107
 None
 1.29A 4rtpA-2vn7A:
undetectable		 4rtpA-2vn7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 0.78A 5btaA-2vn7A:
undetectable
5btaC-2vn7A:
undetectable
5btaD-2vn7A:
undetectable		 5btaA-2vn7A:
21.70
5btaC-2vn7A:
21.70
5btaD-2vn7A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 0.82A 5btaA-2vn7A:
undetectable
5btaB-2vn7A:
undetectable
5btaC-2vn7A:
undetectable		 5btaA-2vn7A:
21.70
5btaB-2vn7A:
17.11
5btaC-2vn7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 0.78A 5btcA-2vn7A:
undetectable
5btcC-2vn7A:
undetectable
5btcD-2vn7A:
undetectable		 5btcA-2vn7A:
21.70
5btcC-2vn7A:
21.70
5btcD-2vn7A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 6 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 0.77A 5btcA-2vn7A:
undetectable
5btcB-2vn7A:
undetectable
5btcC-2vn7A:
undetectable		 5btcA-2vn7A:
21.70
5btcB-2vn7A:
17.11
5btcC-2vn7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 0.82A 5btfA-2vn7A:
undetectable
5btfB-2vn7A:
undetectable
5btfC-2vn7A:
undetectable		 5btfA-2vn7A:
21.70
5btfB-2vn7A:
17.11
5btfC-2vn7A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 1.14A 5cdqA-2vn7A:
undetectable
5cdqB-2vn7A:
undetectable
5cdqC-2vn7A:
undetectable		 5cdqA-2vn7A:
19.55
5cdqB-2vn7A:
15.53
5cdqC-2vn7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 SER A 185
ARG A 122
GLY A 105
GLU A 106
 None
 1.13A 5cdqR-2vn7A:
undetectable
5cdqS-2vn7A:
undetectable
5cdqT-2vn7A:
undetectable		 5cdqR-2vn7A:
19.55
5cdqS-2vn7A:
15.53
5cdqT-2vn7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 9 VAL A 159
LEU A 202
ALA A 203
VAL A 151
ILE A 155
 None
 1.09A 5om2A-2vn7A:
undetectable
5om2B-2vn7A:
undetectable		 5om2A-2vn7A:
8.42
5om2B-2vn7A:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 5 GLY A 174
GLN A 124
VAL A 181
SER A 185
 None
 1.22A 5vunA-2vn7A:
undetectable		 5vunA-2vn7A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 SER A 252
GLY A 308
ALA A 324
SER A 291
VAL A 284
 None
 1.19A 6bqgA-2vn7A:
3.6		 6bqgA-2vn7A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 ALA A 380
TYR A 384
GLN A 356
VAL A 359
 None
 0.96A 6cduA-2vn7A:
undetectable
6cduE-2vn7A:
2.0		 6cduA-2vn7A:
20.17
6cduE-2vn7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 GLN A 356
VAL A 359
ALA A 380
TYR A 384
 None
 0.90A 6cduD-2vn7A:
1.8
6cduE-2vn7A:
2.0		 6cduD-2vn7A:
20.17
6cduE-2vn7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 8 GLN A 356
VAL A 359
ILE A 377
TYR A 384
 None
 0.82A 6cduG-2vn7A:
undetectable
6cduH-2vn7A:
1.8		 6cduG-2vn7A:
20.17
6cduH-2vn7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 7 GLN A 356
VAL A 359
ALA A 380
TYR A 384
 None
 0.95A 6cduH-2vn7A:
1.8
6cduI-2vn7A:
1.6		 6cduH-2vn7A:
20.17
6cduI-2vn7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 12 ALA A 195
PHE A 470
VAL A 154
LEU A 130
ALA A  56
 None
 1.13A 6djzC-2vn7A:
undetectable		 6djzC-2vn7A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 10 LEU A 135
SER A 139
LEU A 142
ILE A 158
SER A 152
 None
 1.26A 6dm2B-2vn7A:
2.8
6dm2C-2vn7A:
3.1		 6dm2B-2vn7A:
11.75
6dm2C-2vn7A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		5 / 10 ILE A 158
SER A 152
LEU A 135
SER A 139
LEU A 142
 None
 1.27A 6dm2A-2vn7A:
3.1
6dm2D-2vn7A:
2.6		 6dm2A-2vn7A:
11.75
6dm2D-2vn7A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		12 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 180
ARG A 309
TYR A 315
TRP A 321
TRP A 421
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
None
 0.46A 6fhwA-2vn7A:
57.8		 6fhwA-2vn7A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		3 / 3 TRP A 178
GLU A 179
GLU A 404
 None
BTB  A 620 (-3.6A)
BTB  A 620 (-4.0A)
 0.39A 6fhwA-2vn7A:
57.8		 6fhwA-2vn7A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		3 / 3 TRP A 421
GLU A 404
GLU A 179
 None
BTB  A 620 (-4.0A)
BTB  A 620 (-3.6A)
 0.90A 6fhwA-2vn7A:
57.8		 6fhwA-2vn7A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		12 / 12 ALA A  38
TYR A  47
TRP A  51
ARG A  53
ASP A  54
TRP A 120
GLY A 121
GLU A 180
ARG A 309
TYR A 315
TRP A 321
TRP A 421
 BTB  A 620 ( 3.8A)
BTB  A 620 (-3.9A)
BTB  A 620 (-3.8A)
BTB  A 620 (-3.7A)
BTB  A 620 (-2.8A)
None
None
None
BTB  A 620 (-3.6A)
BTB  A 620 ( 4.9A)
None
None
 0.46A 6fhwB-2vn7A:
58.1		 6fhwB-2vn7A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 2vn7 GLUCOAMYLASE
(Trichoderma
reesei) 		4 / 4 TRP A 178
GLU A 179
GLU A 404
LEU A 419
 None
BTB  A 620 (-3.6A)
BTB  A 620 (-4.0A)
None
 0.43A 6fhwB-2vn7A:
58.1		 6fhwB-2vn7A:
9.38