SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2vnl BIFUNCTIONAL TAIL
PROTEIN, PIIGCN4
(Saccharomyces
cerevisiae;
Salmonella
virus
P22) 		4 / 5 LEU A  79
ILE A  16
PRO A  15
PHE A  17
 None
 1.17A 3s3vA-2vnlA:
undetectable		 3s3vA-2vnlA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2vnl BIFUNCTIONAL TAIL
PROTEIN, PIIGCN4
(Saccharomyces
cerevisiae;
Salmonella
virus
P22) 		3 / 3 LYS A  81
VAL A  83
HIS A  58
 None
 1.12A 3tj7A-2vnlA:
undetectable		 3tj7A-2vnlA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnl BIFUNCTIONAL TAIL
PROTEIN, PIIGCN4
(Saccharomyces
cerevisiae;
Salmonella
virus
P22) 		3 / 3 VAL A  80
TYR A  75
GLN A  78
 None
GOL  A 283 (-4.3A)
None
 0.72A 5qgkA-2vnlA:
undetectable		 5qgkA-2vnlA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnl BIFUNCTIONAL TAIL
PROTEIN, PIIGCN4
(Saccharomyces
cerevisiae;
Salmonella
virus
P22) 		3 / 3 VAL A  80
TYR A  75
GLN A  78
 None
GOL  A 283 (-4.3A)
None
 0.75A 5qgrA-2vnlA:
undetectable		 5qgrA-2vnlA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2vnl BIFUNCTIONAL TAIL
PROTEIN, PIIGCN4
(Saccharomyces
cerevisiae;
Salmonella
virus
P22) 		3 / 3 VAL A  80
TYR A  75
GLN A  78
 None
GOL  A 283 (-4.3A)
None
 0.76A 5qgtA-2vnlA:
undetectable		 5qgtA-2vnlA:
20.40