SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2vnr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 2vnr CPE0329
(Clostridium
perfringens) 		4 / 5 TYR A 198
PRO A  68
THR A 105
THR A  53
 None
 1.45A 1ymxB-2vnrA:
undetectable		 1ymxB-2vnrA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2vnr CPE0329
(Clostridium
perfringens) 		5 / 10 ILE A  80
ALA A 201
LEU A 183
LEU A 122
SER A 104
 None
 1.14A 2w9sF-2vnrA:
undetectable		 2w9sF-2vnrA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 2vnr CPE0329
(Clostridium
perfringens) 		5 / 10 TYR A 151
VAL A 170
SER A 120
TYR A 198
ILE A 141
 None
 1.31A 3vriA-2vnrA:
undetectable
3vriC-2vnrA:
undetectable		 3vriA-2vnrA:
18.68
3vriC-2vnrA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 2vnr CPE0329
(Clostridium
perfringens) 		4 / 7 THR A 165
GLY A 123
VAL A 197
GLY A 193
 None
 0.82A 4forA-2vnrA:
undetectable		 4forA-2vnrA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 2vnr CPE0329
(Clostridium
perfringens) 		5 / 11 PHE A 118
SER A 120
ALA A 201
THR A  98
ALA A 100
 None
 1.40A 6efnA-2vnrA:
undetectable		 6efnA-2vnrA:
18.64